Abstract Mean cell size at division is generally constant for specific conditions and types, but the mechanisms coupling growth cycle control with regulation are poorly understood in intact tissues. Here we show that continuously dividing fields of cells within shoot apical meristem Arabidopsis dynamic mean dependent on developmental stage, genotype environmental signals. We length effectively predicted using a two-stage model linking two sequential cyclin kinase (CDK) activities,...

Experience alters brain structure, but the underlying mechanism remained unknown. Structural plasticity reveals that function is encoded in generative changes to cells compete with destructive processes driving neurodegeneration. At an adult critical period, experience increases fiber number and size Drosophila. Here, we asked if Toll receptors are involved. Tolls demarcate a map of anatomical domains. Focusing on Toll-2, loss caused apoptosis, neurite atrophy impaired behaviour. Toll-2 gain...

Neurotrophic interactions occur in Drosophila, but to date, no neurotrophic factor had been found. Neurotrophins are the main vertebrate secreted signalling molecules that link nervous system structure and function: they regulate neuronal survival, targeting, synaptic plasticity, memory cognition. We have identified a flies, Drosophila Neurotrophin (DNT1), structurally related all known neurotrophins highly conserved insects. By investigating with genetics consequences of removing DNT1 or...

The early and accurate detection of Distributed Denial Service (DDoS) attacks is a fundamental area research to safeguard the integrity functionality organizations’ digital ecosystems. Despite growing importance neural networks in recent years, use classical techniques remains relevant due their interpretability, speed, resource efficiency, satisfactory performance. This article presents results comparative analysis six machine learning techniques, namely, Random Forest (RF), Decision Tree...

Organisms are structurally robust, as cells accommodate changes preserving structural integrity and function. The molecular mechanisms underlying robustness plasticity poorly understood, but can be investigated by probing how respond to injury. Injury the CNS induces proliferation of enwrapping glia, leading axonal re-enwrapment partial functional recovery. This glial regenerative response is found across species, may reflect a common genetic mechanism. Here, we show that injury Drosophila...

Summary Tuberculosis and other kinds of mycobacteriosis are serious illnesses for which early diagnosis is critical disease control. Sputum sample analysis a common manual technique employed bacillus detection but current sample‐analysis techniques time‐consuming, very tedious, subject to poor specificity require highly trained personnel. Image‐processing pattern‐recognition appropriate tools improving the screening samples. Here we present new sputum image that combines invariant shape...

Retrograde growth factors regulating synaptic plasticity at the neuromuscular junction (NMJ) in Drosophila have long been predicted but their discovery has scarce. In vertebrates, such retrograde produced by muscle include GDNF and neurotrophins (NT: NGF, BDNF, NT3 NT4). NT superfamily members identified throughout invertebrates, so far no functional vivo analysis carried out NMJ invertebrates. The family of proteins is formed DNT1, DNT2 Spätzle (Spz), with sequence, structural conservation...

Currently, there are no free databases of 3D point clouds and images for seedling phenotyping. Therefore, this paper describes a platform scanning using Lidar with which database was acquired use in plant phenotyping research. In total, 362 maize seedlings were recorded an RGB camera SICK LMS4121R-13000 laser scanner angular resolutions 45° 0.5° respectively. The scanned plants diverse, captures ranging from less than 10 cm to 40 cm, 7 24 days after planting different light conditions indoor...

Circulating microRNAs (miRNAs) have aroused a lot of interest as reliable blood diagnostic biomarkers Alzheimer’s disease (AD). Here, we investigated the panel expressed miRNAs in response to aggregated Aβ1–42 peptides infused hippocampus adult rats mimic events early onset non-familial AD disorder. led cognitive impairments associated with an astrogliosis and downregulation circulating miRNA-146a-5p, -29a-3p, -29c-3p, -125b-5p, and-191-5p. We established kinetics expression selected found...

Tuberculosis is a serious illness which control mainly based on presumptive diagnosis. A technique commonly used consists of analyzing sputum images for detecting bacilli. However, the analysis quite expensive, time consuming and requires highly trained personnel to avoid high errors. Image processing techniques provide good tool improving manual screening samples. In this paper we present new bacilli detection with aim attain specificity rate therefore reducing required analyze such This...

Abstract Evidence of molecular and functional homology between vertebrate Drosophila glia is limited, restricting the power as a model system to unravel basis glial function. Like in vertebrates, central nervous cells are produced excess surplus eliminated by apoptosis adjusting final number axons. The underlying mechanisms largely unknown, only gliatrophic pathway known date flies EGFR its ligands. PDGFR signaling plays major role regulating oligodendrocyte migration vertebrates. Here, we...

Bank fraud detection faces critical challenges in imbalanced datasets, where fraudulent transactions are rare, severely impairing model generalization. This study proposes a Gaussian noise-based augmentation method to address class imbalance, contrasting it with SMOTE and ADASYN. By injecting controlled perturbations into the minority class, our approach mitigates overfitting risks inherent interpolation-based techniques. Five classifiers, including XGBoost convolutional neural network...

Development, cancer, neurodegenerative and demyelinating diseases, injury, stem cell manipulations are characterised by alterations in number. Research into development, disease, the effects of drugs require number counts. These generally indirect estimates, because counting cells an animal or organ is paradoxically difficult, as well being tedious unmanageable. Drosophila a powerful model organism used to investigate genetic bases development disease. There models for multiple increase...

In angiosperms, double fertilization of the egg and central cell megagametophyte leads to development embryo endosperm, respectively. Control cycle progression in is essential for successful development. Central cell-targeted expression D-type cyclin CYCD7;1 (end CYCD7;1) using imprinted FWA promoter overcomes arrest Arabidopsis female gametophyte unfertilized ovule, leading multinucleate cells at high frequency. Unlike FERTILIZATION-INDEPENDENT SEED (fis) mutants, but similar lethal...

Brachiaria grasses are sown in tropical regions around the world, especially Neotropics, to improve livestock production. Waterlogging is a major constraint productivity and persistence of during rainy season. While some cultivars moderately tolerant seasonal waterlogging, none commercial combines superior yield potential nutritional quality with high level waterlogging tolerance. The breeding program at International Center for Tropical Agriculture (CIAT), has been using recurrent selection...

Forecasting has become essential in different economic sectors for decision making local and regional policies. Therefore, the aim of this paper is to use compare performance two linear models predict future values a measure real profit group companies fashion sector, as financial strategy determine behavior industry. With forecasting purposes, Exponential Smoothing (ES) autoregressive integrated moving averages (ARIMA) were used yearly data. ES ARIMA are widely statistical methods time...

Summary Identification and counting of cells is necessary to test biological hypotheses, for instance nervous system formation, disease, degeneration, injury regeneration, but manual time consuming, tedious, subject bias. The fruit fly Drosophila a widely used model organism analyse gene function, most research carried out in the intact animal or whole organs, rather than cell culture. Inferences on function require that counts are known from these sample types. Image processing pattern...

Precision agriculture has greatly benefited from advances in machine vision and image processing techniques. The use of feature descriptors detectors allows to find distinctive keypoints an the this approach for agronomical applications become a widespread field study. By combining near infrared (NIR) images, acquired with modified Nikon D80 camera, visible spectrum (VIS) D300s, proper crop identification could be obtained. Still, different sensors brings matching challenge due difference...

Morris water maze (MWM) test is widely used to evaluate the learning and memory deficits in rodents. Image processing pattern recognition can be analyse videos recognize automatically tracking MWM. There are several commercial free access software that allows analyzing behavioral tasks although they also have limitations such as automation, cost, user intervention among other things. The aim of this paper was develop a new image technique track rat MWM, which we called RatsTrack. MWM...

Hardness is one of the most crucial mechanical properties, serving as a key indicator material's suitability for specific applications and its resistance to fracturing or deformation under operational conditions. Machine learning techniques have emerged valuable tools swiftly accurately predicting material behavior. In this study, regression methods including decision trees, adaptive boosting, extreme gradient random forest were employed forecast Vickers hardness values based solely on...

Phytoplankton such as diatoms or desmids are useful for monitoring water quality. Manual image analysis is impractical due to the huge diversity of this group microalgae and its great morphological plasticity, hence importance automating procedure. High-resolution images phytoplankton cells can now be acquired by digital microscopes, which facilitate identification process specimens. Therefore, new systems potentially advantageous compared manual methods counting solution identification....

Cell number changes during normal development, and in disease (e.g., neurodegeneration, cancer). Many genes affect cell number, thus functional genetic analysis frequently requires of alterations upon loss function mutations or gain experiments. Drosophila is a most powerful model organism to investigate the involved development vivo. Image processing pattern recognition techniques can be used extract information from microscopy images quantify automatically distinct cellular features, but...