A5047020009- Inflammatory mediators and NSAID effects
- Renal function and acid-base balance
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Cardiac electrophysiology and arrhythmias
- Colorectal Cancer Screening and Detection
- Cancer, Lipids, and Metabolism
- Eicosanoids and Hypertension Pharmacology
- DNA Repair Mechanisms
- Genetic factors in colorectal cancer
- Mitochondrial Function and Pathology
- Cardiac Imaging and Diagnostics
- Contact Dermatitis and Allergies
- Head and Neck Anomalies
- Abdominal Trauma and Injuries
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Research and Treatments
- Macrophage Migration Inhibitory Factor
- Photosynthetic Processes and Mechanisms
- Traumatic Brain Injury and Neurovascular Disturbances
- GDF15 and Related Biomarkers
- Nuclear Receptors and Signaling
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gut microbiota and health
- Neuroscience of respiration and sleep
Harvard University
2017-2021
University of Vermont
2019-2021
Brigham and Women's Hospital
2019-2021
Massachusetts General Hospital
2017-2020
University of Milan
1982-2004
Ospedale Maggiore
1983
Accurate chromosome segregation during meiosis relies on the prior establishment of at least one crossover recombination event between homologous chromosomes. Most meiotic intermediates that give rise to interhomolog crossovers are embedded within a hallmark chromosomal structure called synaptonemal complex (SC), but mechanisms coordinate processes SC assembly (synapsis) and remain poorly understood. Among known structural components budding yeast SC, Zip1 protein is unique for its...
Low-dose aspirin is recommended by the U.S. Preventive Services Task Force for primary prevention of colorectal cancer in certain individuals. However, broader implementation will require improved precision approaches to identify those most likely benefit. The major urinary metabolite PGE2, 11α-hydroxy-9,15-dioxo-2,3,4,5-tetranor-prostane-1,20-dioic acid (PGE-M), a biomarker risk, but it unknown whether PGE-M modifiable individuals at risk cancer. Adults (N = 180) who recently underwent...
Although aspirin is recommended for the prevention of colorectal cancer, specific individuals whom benefits outweigh risks are not clearly defined. Moreover, precise mechanisms by which reduces risk cancer unclear. We recently launched ASPirin Intervention REDuction (ASPIRED) trial to address these uncertainties. ASPIRED a prospective, double-blind, multidose, placebo-controlled, biomarker clinical use in previously diagnosed with adenoma. Individuals (n = 180) will be randomized 1:1:1 ratio...
Background US of the thyroid bed in patients with cancer often depicts small lesions, but it is unclear whether characteristics lesions can help predict recurrence. Purpose To determine size or features after thyroidectomy conjunction clinical Materials and Methods With use a reporting database, all imaged between July 2006 June 2016 an indication post-thyroidectomy follow-up were retrospectively identified. Recorded data included patient demographic characteristics; date thyroidectomy;...
<div>Abstract<p>Low-dose aspirin is recommended by the U.S. Preventive Services Task Force for primary prevention of colorectal cancer in certain individuals. However, broader implementation will require improved precision approaches to identify those most likely benefit. The major urinary metabolite PGE<sub>2</sub>, 11α-hydroxy-9,15-dioxo-2,3,4,5-tetranor-prostane-1,20-dioic acid (PGE-M), a biomarker risk, but it unknown whether PGE-M modifiable individuals at risk...
<div>Abstract<p>Low-dose aspirin is recommended by the U.S. Preventive Services Task Force for primary prevention of colorectal cancer in certain individuals. However, broader implementation will require improved precision approaches to identify those most likely benefit. The major urinary metabolite PGE<sub>2</sub>, 11α-hydroxy-9,15-dioxo-2,3,4,5-tetranor-prostane-1,20-dioic acid (PGE-M), a biomarker risk, but it unknown whether PGE-M modifiable individuals at risk...
<p>Supplemental Methods, References, Figure, and Tables</p>
<p>Supplemental Methods, References, Figure, and Tables</p>
The authors have explored the early modifications of systolic time intervals in 90 patients hospitalized as emergency cases for acute myocardial infarction. From analysis and interpretation collected data they conclude that such considerable prognostic value. All fitting specifications NYHA classes I II, but at same showing a shortening isometric contraction to less than 39 +/- 1.4 ms turned out constitute high-risk group development major mechanical electrical complications next 2 weeks.