A5084146359- Gastrointestinal motility and disorders
- Gastroesophageal reflux and treatments
- Pelvic floor disorders treatments
- Congenital gastrointestinal and neural anomalies
- Eosinophilic Esophagitis
- Diverticular Disease and Complications
- Child Nutrition and Feeding Issues
- Helicobacter pylori-related gastroenterology studies
- Microscopic Colitis
- Eating Disorders and Behaviors
- Diet and metabolism studies
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Pathogenesis and Treatment of Hiccups
- Colorectal Cancer Screening and Detection
- Dysphagia Assessment and Management
- Anorectal Disease Treatments and Outcomes
- Inflammatory Bowel Disease
- Inflammatory mediators and NSAID effects
- Gut microbiota and health
- Infant Health and Development
- Obesity, Physical Activity, Diet
- Sleep and related disorders
- Colorectal Cancer Treatments and Studies
- Nutrition and Health in Aging
Massachusetts General Hospital
2016-2025
Harvard University
2016-2025
MGH Institute of Health Professions
2025
New York Hospital Queens
2024
Brigham and Women's Hospital
2024
Columbia University
2024
NewYork–Presbyterian Hospital
2024
Michigan Medicine
2023
Taipei Medical University
2023
Taipei Medical University-Shuang Ho Hospital
2023
See editorial on page 336. ChatGPT (OpenAI) is a 175 billion–parameter large language model (LLM) artificial intelligence (AI) that was released in November 2022. developed based the generative pretrained transformer (GPT) 3.5 natural processing technology and provides conversational text response to given prompt.1OpenAI.https://openai.com/blog/chatgptDate accessed: February 8, 2023Google Scholar One potential application of answering patients' medical questions. With more than 70 million...
Abstract Coordinated cell interactions within the esophagus maintain homeostasis, and disruption can lead to eosinophilic esophagitis (EoE), a chronic inflammatory disease with poorly understood pathogenesis. We profile 421,312 individual cells from esophageal mucosa of 7 healthy 15 EoE participants, revealing 60 subsets functional alterations in states, compositions, that highlight previously unclear features EoE. Active displays enrichment ALOX15 + macrophages, PRDM16 dendritic expressing...
We extend previous studies on the impact of masks COVID-19 outcomes by investigating an unprecedented breadth and depth health outcomes, geographical resolutions, types mask mandates, early versus later waves controlling for other government interventions, mobility testing rate weather. show that mandates are associated with a statistically significant decrease in new cases (-3.55 per 100K), deaths (-0.13 proportion hospital admissions (-2.38 percentage points) up to 40 days after...
Abstract Objective Little research exists on Rome IV disorders of gut–brain interaction (DGBI; formerly called functional gastrointestinal disorders) in outpatients with eating (EDs). These data are particularly lacking for avoidant/restrictive food intake disorder (ARFID), which shares core features DGBI. We aimed to identify the frequency and nature DGBI symptoms among EDs. Method Consecutively referred pediatric adult patients diagnosed an ED ( n = 168, 71% female, ages 8–76 years) our...
Abstract Background Previous studies show some patients with functional gastrointestinal disorders (disorders of gut‐brain interaction) may be at risk for or already have an eating disorder (ED). Avoidant/restrictive food intake (ARFID) (ED not primarily motivated by body shape/weight concerns) particularly relevant but previous been unable to fully apply diagnostic criteria. This study aimed determine the frequency and nature full spectrum ED symptoms, among adults interaction. Methods...
Abstract Background Exclusion diets for gastrointestinal symptom management have been hypothesized to be a risk factor avoidant/restrictive food intake disorder (ARFID; non‐body image‐based eating disorder). In retrospective study of pediatric and adult neurogastroenterology patients, we aimed (1) identify the prevalence characteristics an exclusion diet history (2) evaluate if was concurrently associated with presence ARFID symptoms. Methods We conducted chart review 539 consecutive...
tions.We evaluated the joint association of dietary and lifestyle factors with risk GERD symptoms.
The critical role of the gut microbiome in microscopic colitis (MC) is evident by observation that fecal diversion associated with resolution mucosal inflammation while restoration stream recurrence disease.1 Characterization composition and function MC therefore could provide insights into disease pathogenesis.
Google Trends is an online tool that allows measurement of search term popularity on Google, spatially and temporally. While not epidemiological for determining incidence, it can estimate the a certain disease by volume over time.1,2 It has previously correlated well with infectious incidence demonstrated utility in forecasting, especially influenza data.3 We utilized to investigate whether interest common gastrointestinal (GI) symptoms would correlate coronavirus 2019 (COVID-19) data.
Low-dose aspirin is recommended by the U.S. Preventive Services Task Force for primary prevention of colorectal cancer in certain individuals. However, broader implementation will require improved precision approaches to identify those most likely benefit. The major urinary metabolite PGE2, 11α-hydroxy-9,15-dioxo-2,3,4,5-tetranor-prostane-1,20-dioic acid (PGE-M), a biomarker risk, but it unknown whether PGE-M modifiable individuals at risk cancer. Adults (N = 180) who recently underwent...