- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- ECG Monitoring and Analysis
- Cardiac pacing and defibrillation studies
- Chaos-based Image/Signal Encryption
- Cardiac Valve Diseases and Treatments
- Cellular Automata and Applications
- Fractal and DNA sequence analysis
- EEG and Brain-Computer Interfaces
- Neuroscience and Neural Engineering
- Authorship Attribution and Profiling
- Ancient and Medieval Archaeology Studies
- Heart Rate Variability and Autonomic Control
- Chaos control and synchronization
- Natural Language Processing Techniques
- Non-Invasive Vital Sign Monitoring
- Cardiac Imaging and Diagnostics
- Algorithms and Data Compression
- Advanced Control Systems Optimization
- Neural Networks and Applications
- Cryptographic Implementations and Security
- Fault Detection and Control Systems
- Ancient Mediterranean Archaeology and History
- Advanced Chemical Sensor Technologies
University of Lausanne
2019-2025
University Hospital of Lausanne
2023-2025
École Polytechnique Fédérale de Lausanne
2014-2022
Sapienza University of Rome
2021
ASTRA National Museum Complex
2019
Universitatea Națională de Știință și Tehnologie Politehnica București
2006-2012
Supélec
2010
Fibrillatory wave amplitude (fWA) on 12-lead ECG predicts the outcome of ablation in atrial fibrillation (AF). We hypothesized that changes fWA following wide circumferential isolation pulmonary veins (WPVI) persistent AF (peAF) is a better predictor compared to baseline fWA. Eighty-nine patients (sustained peAF 7 ± months) underwent first-time WPVI. Sixty-second signals devoid QRST waves were recorded at and end WPVI (endWPVI). for each lead mean (meanfWA) across computed. Patients with...
Abstract Aims Stereotactic arrhythmia radioablation (STAR) has been recently introduced for the management of therapy-refractory ventricular tachycardia (VT). VT recurrences have reported after STAR but mechanisms remain largely unknown. We analysed in our patients STAR. Methods and results From 09.2017 to 01.2020, 20 (68 ± 8 y, LVEF 37 15%) suffering from refractory were enrolled, 16/20 with a history at least one electrical storm. Before STAR, an invasive electroanatomical mapping (Carto3)...
Identification of persistent AF (PsAF) patients who may be cured with stand-alone pulmonary vein isolation (PVI) would allow more efficient ablation strategies. Intuitively, the benefit PVI is expected to lower when PVs are poorly connected, but this assumption has never been tested. Evaluate whether circumferential extent PV connections assessed pre-ablation predicts success rate PVI. Consecutive PsAF undergoing first were included. The electrical connection was using a circular mapping...
Implantable cardioverter defibrillators (ICD) are recommended in patients with left ventricular ejection fraction (LVEF) below or equal to 35%. However, no recommendation exists guide the use of prophylactic ICD less altered LVEF and myocardial scarring, even though they represent majority sudden cardiac deaths (SCD). To evaluate prognostic value programmed stimulation (PVS) mildly reduced preserved LVEF. Patients who underwent PVS scarring ≥ 40% were included. The primary endpoint was...
Abstract Title Evaluating the Efficiency, Safety, and Midterm Outcomes of 3D Imaging Assistance in Atrial Fibrillation Cryoballoon Ablation Introduction Pulmonary vein (PV) isolation is a cornerstone therapy for symptomatic atrial fibrillation (AF). While 3D-navigation technologies commonly used with radiofrequency (RF) ablation significantly reduce X-ray exposure by providing enhanced anatomical detail, cryoballoon (CBA) still relies on conventional fluoroscopy, resulting considerable...
Abstract Background Pulsed Field Ablation (PFA) is emerging as a reliable energy source for pulmonary vein isolation (PVI) in the treatment of atrial fibrillation (AF). Accurate dose titration essential to prevent reversible electroporation and optimize tissue response. Purpose To determine utility automated analysis unipolar electrograms (EGMs) pre- post-PFA delivery assessing Methods Unfiltered EGMs were acquired using proprietary pentaspline basket catheter (Boston Scientific Inc., USA)...
We propose two methods for generating binary sequences complying with a fair coin tossing model, starting from the tent map. The are supported theoretically and experimentally. As map is described by uniform probability law, statistical independence of successive symbols main problem under discussion. A first method transforms values into sequence means comparison threshold chosen equal to parameter. Considering type II error involved in test coin, it was shown that appropriate parameter,...
The paper evaluates, by means of an original statistical procedure, the minimum sampling distance that enables to extract statistically independent random variables from tent map. experimental results indicate relationship among map parameter and independence decision. study may guide selection suitable for different applications where is interest.
Background Cardiac sarcoidosis is associated with heart failure, conduction abnormalities, and life-threatening arrhythmias including ventricular tachycardia (VT). Radiotherapy has been suggested as a treatment for extra-cardiac in patients refractory to immunomodulatory treatment. Methods The effectiveness safety of low-dose whole-heart radiotherapy therapy cardiac were evaluated pre- post-intervention case report comparing the 54 months before after Immunomodulatory irradiation consisted 2...
Background: Consistently successful patient outcomes following catheter ablation (CA) for treatment of persistent atrial fibrillation (pers-AF) remain elusive. We propose an electrocardiogram (ECG) analysis designed to (1) refine selection patients most likely benefit from ablation, and (2) examine the temporal evolution AF organization indices that could act as clinical indicators ongoing effectiveness completeness. Method: Twelve-lead ECG was continuously recorded in 40 (61 ± 8 years)...
As a contribution to 2017 Physionet/CinC challenge, this work aims at the classification of different ECG heart rhythms.The importance rhythm cannot be understated, as rhythms such atrial fibrillation have been associated with stroke, coronary artery disease and mortality.Automatic detection remains challenging task, they can episodic unpredictable characteristics.In CinC2017 training set contains 8528 single lead short-term ECGs (9-90s, 300 Hz).Recordings are categorized into four classes...
This paper addresses the stabilization problem of a class linear discrete-time systems with input delays. More precisely, by taking into account presence input/state constraints, an analysis safety functioning is performed based on admissible set description.
Superimposition of farfield (FF) and nearfield (NF) bipolar voltage electrograms (BVE) complicates the confirmation pulmonary vein (PV) isolation after catheter ablation atrial fibrillation. Our aim was to develop an automatic algorithm based on a single-beat analysis discriminate PV NF from FF BVE circular mapping during cryoballoon isolation.During freezing cycles in cryoablation PVI, local distant signals were recorded, identified labelled. BVEs classified using four different machine...
Stereotactic arrhythmia radioablation (STAR) appears to be beneficial in selected patients with therapy-refractory ventricular tachycardia (VT). However, high-dose radiotherapy used for STAR-treatment may affect functioning of the patients' implantable cardioverter defibrillator (ICD) by direct effects radiation on ICD components or cardiac tissue. Currently, effect STAR remains unknown.A retrospective pre-post multicenter study evaluating 12-month before and after was performed. Patients...
In spite of the progress in management Atrial Fibrillation (AF), this arrhythmia is one major causes stroke and heart failure.The progression pathology from a silent paroxysmal form (PAF) into sustained AF can be prevented by predicting onset PAF episodes.Moreover, since caused heterogeneous mechanisms different patients, as we demonstrate paper, patient-specific approach offers promising solution.In work, consider two ECG recordings, close to far away any episode.For each patient, extract...
This paper concerns the problem of generating iid (identically and independently distributed) discrete data sets starting from logistic function. We decide upon independence by combining information theory elements (the noisy channel its corresponding entities) with test in contingency tables.
By resuming and extending an original method for verifying natural language stationarity, the paper presents a study on statistical structures of words word digrams (groups two successive words) in printed Romanian. The also contains evaluation redundancy based digrams. experimental was carried out literary linguistic corpus novels short stories summing up over 12.5 million with orthography punctuation marks.
The termination of long-standing persistent atrial fibrillation (LS-pAF) can be achieved by stepwise catheter ablation (step-CA) within the left atrium (LA). Our study aims to applying complexity measures derived from nonlinear time series analysis in order characterize LS-pAF terms organization and identify patients whom AF terminated those cannot step-CA LA. A total 33 consecutive (age 61 ± 7 years, sustained duration 19 11 months) with underwent step-CA. right bipolar electrograms before...