A5020771412- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
- Viral Infections and Immunology Research
- Animal Disease Management and Epidemiology
- Vector-Borne Animal Diseases
- Influenza Virus Research Studies
- Veterinary medicine and infectious diseases
- Veterinary Oncology Research
- Advanced biosensing and bioanalysis techniques
- Healthcare and Venom Research
- Viral Infectious Diseases and Gene Expression in Insects
- Respiratory viral infections research
- Hepatitis Viruses Studies and Epidemiology
- Virology and Viral Diseases
- Reproductive Biology and Fertility
- Drug Transport and Resistance Mechanisms
- Milk Quality and Mastitis in Dairy Cows
- Primate Behavior and Ecology
- Berberine and alkaloids research
- Turtle Biology and Conservation
- Growth Hormone and Insulin-like Growth Factors
- Antibiotic Resistance in Bacteria
- Parasitic Infections and Diagnostics
- Pediatric Hepatobiliary Diseases and Treatments
Konkuk University
2015-2024
Kansas State University
2014-2018
National Research Institute for Veterinary Virology and Microbiology of Russia
2018
Animal and Plant Quarantine Agency
1996
Iowa State University
1988-1995
Veterinary Medical Teaching Hospital
1988-1994
Hepatitis E virus (HEV) is a very important public health concern in many developing countries where epidemics of hepatitis are common. Sporadic cases clinical not only occur these but also uncommonly patients with no known epidemiological exposure to HEV industrialized countries. The source infection unknown it has been suggested that animals might serve as reservoir for both settings. We recently identified and characterized an strain (swine HEV) infects large numbers pigs the United...
Background Adult stem cells have been widely investigated in bioengineering approaches for tissue repair therapy. We evaluated the clinical value and safety of application cultured bone marrow‐derived allogenic mesenchymal ( MSC s) treating skin wounds a canine model. Hypothesis Topical transplantation can accelerate closure experimental full‐thickness cutaneous attenuate local inflammation. Animals healthy beagle dogs n = 10; 3–6 years old; 7.2–13.1 kg) were studied. Methods Full‐thickness...
ABSTRACT Sporadic human infections by a novel H7N9 virus occurred over large geographic region in China. In this study, we show that Newcastle disease (NDV)-vectored H7 (NDV-H7) and NDV-H5 vaccines are able to induce antibodies with high hemagglutination inhibition (HI) titers completely protect chickens from challenge the or highly pathogenic H5N1 viruses, respectively. Notably, baculovirus-expressed protein failed infection.
The fact that there have been more than 300 human infections with a novel avian H7N9 virus in China indicates this emerging strain has pandemic potential. Furthermore, many of the viruses circulating animal reservoirs contain putative mammalian signatures HA and PB2 genes are believed to be important adaptation other strains humans. To date, definitive roles these mammalian-signature substitutions transmission pathogenesis remain unclear. address we analyzed biological characteristics,...
A novel porcine circovirus 3 (PCV3) was first detected in pigs showing dermatitis and nephropathy syndrome, reproductive failure, multisystemic inflammation the USA. Herein, we report on PCV3 as a potential etiological agent of clinical signs, failure respiratory distress Korean pig farms, based situ hybridization, pathological, molecular findings. Confirmation presence may increase co-infection with other causative agents disease herds, indicating need for further systemic investigation...
Porcine respiratory coronavirus (PRCV) is a member of the species Alphacoronavirus 1 within genus family Coronaviridae. A few studies have been conducted on prevalence PRCV since its first identification in 1997, but there no recent and genetic characterization virus Korea. In this study, seroprevalence was determined Korean pig farms using commercially available TGEV/PRCV differential enzyme-linked immunosorbent assay kit. The farm-level to be 68.6% (48/70), similar previous reports Korea,...
Torque teno virus (TTV) is a recently identified that has wide range of host tropisms from humans to shrews. Human TTV and mini are distributed worldwide, their high prevalence in human populations been reported. Pigs have own species-specific TTV, like porcine also Despite its prevalence, the role TTV-related disease or syndrome pigs not determined. In swine industry, thought be one agents aggravate clinical manifestation Porcine circovirus-associated (PCVAD), newly emerging, economically...
Modified live vaccines (MLVs) based on genotype 1 strains, particularly C-strain, have been used to prevent and control classical swine fever virus (CSFV) worldwide. Nevertheless, a shift in the predominant CSFV strains circulating field from or 3 2 is seen. Genotype genetically distant vaccine was recently reported during outbreaks after failure; this has raised concerns that vaccination influenced viral evolution. In Korea 2016, there an unexpected CSF outbreak MLV-vaccinated commercial...
P-glycoprotein (P-gp), which is encoded by the multidrug resistance gene (MDR-1); alpha fetoprotein (AFP); and vascular endothelium-associated antigens are well-known markers for human canine hepatic diseases. We obtained liver tissues from 5 dogs with hepatocellular carcinoma (HCC) 12 cirrhosis, we performed histopathologic immunohistochemical evaluations using anti-P-gp, anti-AFP, anti-CD31, anti-CD34 antibodies. P-gp was expressed at higher levels in HCC than cirrhotic livers ( P <...
Rapid and specific detection of foot-and-mouth disease virus (FMDV) is a key factor for promoting prompt control FMD outbreaks. In this study, real-time reverse transcription loop-mediated isothermal amplification (RRT-LAMP) assay with high sensitivity, rapidity reliability was developed using targeted gene-specific assimilating probe seven FMDV serotypes. Positive signals were generated within 15 min the lowest concentration standard RNA sample at 62°C; substantially faster than that...