A5057876059- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
- Veterinary Oncology Research
- Animal Disease Management and Epidemiology
- Reproductive Biology and Fertility
- Viral Infections and Immunology Research
- Herpesvirus Infections and Treatments
- Clostridium difficile and Clostridium perfringens research
- SARS-CoV-2 and COVID-19 Research
- Veterinary Medicine and Surgery
- Plant Virus Research Studies
- Dermatological diseases and infestations
- Ear and Head Tumors
- Renal and related cancers
- Microbial infections and disease research
- Endometriosis Research and Treatment
- Oral and Maxillofacial Pathology
- Head and Neck Surgical Oncology
- Salivary Gland Tumors Diagnosis and Treatment
- Transplantation: Methods and Outcomes
- Parkinson's Disease Mechanisms and Treatments
- Parasite Biology and Host Interactions
- Identification and Quantification in Food
- Neurofibromatosis and Schwannoma Cases
Komipharm International (South Korea)
2022
Jeju National University
2007-2011
Porcine reproductive and respiratory syndrome virus (PRRSV) is a globally endemic, costly swine arterivirus with wide genetic antigenic variations, leading to the frequent appearance of novel virulent strains that hampers PRRSV control. Recently, NADC30‐like (lineage 1C, L1C) NADC34‐like 1A, L1A) were reported be prevalent in mainland South Korea became main epidemic persistently attributed outbreaks nationwide, raising great concern domestic pork industry. Although genotypic pathotypic...
Modified live vaccines (MLVs) based on genotype 1 strains, particularly C-strain, have been used to prevent and control classical swine fever virus (CSFV) worldwide. Nevertheless, a shift in the predominant CSFV strains circulating field from or 3 2 is seen. Genotype genetically distant vaccine was recently reported during outbreaks after failure; this has raised concerns that vaccination influenced viral evolution. In Korea 2016, there an unexpected CSF outbreak MLV-vaccinated commercial...
Epidemiological characteristics of swine pulmonaryPneumocystis (P.) carinii and concurrent infections were surveyed on Jeju Island, Korea, within a designated period in 172 pigs submitted from 54 farms to the Department Veterinary Medicine, National University.The cases evaluated by histopathology, immunohistochemistry, PCR/RT-PCR, bacteriology.P. infection was confirmed 39 (22.7%) pigs.Histopathologically, lungs had moderate severe lymphohistioctyic interstitial pneumonia with variable...
Destruction of dopaminergic neurons in the substantia nigra pars compacta (SNpc) is a common pathophysiology Parkinson's disease (PD). Characteristics PD patients include bradykinesia, muscle rigidity, tremor at rest and disturbances balance. For about four decades, animal models have been produced by toxin-induced or gene-modified techniques. However, mice, none showed all 4 major criteria PD. Moreover, distinguishing between model pigs normal has not well established. Therefore, we planned...
Introduction Research quality can be improved with reliable and reproducible experimental results when animal experiments are conducted using laboratory animals guaranteed microbiological genetic through health monitoring. Therefore, monitoring requires the rapid accurate diagnosis of infectious diseases in animals. Methods This study presents a performance evaluation commercially available multiplex real-time PCR (mRT-PCR) assay for detection 12 pathogens (Set 1: Sendai virus [SeV, formally...
Swine hepatitis E virus (HEV) is an emerging zoonotic pathogen due to its close genomic similarity human HEV.The prevalence of swine HEV in the hepatic lesion pigs from Jeju Island was investigated by reverse transcriptase polymerase chain reaction (RT-PCR).In total, 40 with lesions were selected 19 different farms, based on examination microscopy.RT-PCR findings revealed 22 cases (55%), including 18 suckling and 4 growing pigs.Several histopathological lesions, multifocal lymphoplasmacytic...
Despite the routine use of porcine reproductive and respiratory syndrome (PRRS)-modified live vaccines, serious concerns are currently being raised due to their quick reversion virulence limited cross-protection against divergent PRRS virus (PRRSV) strains circulating in field. Therefore, a chimeric vaccine (JB1) was produced using DNA-launched infectious clone by replacing open reading frames (ORFs) 3-6 with those from mixture two genetically different PRRSV2 (K07-2273 K08-1054) ORF1a that...
A 4-week-old male piglet being maintained in a research facility was found dead without any previous clinical signs.The had been born from surrogate mother after somatic nuclear transfer as part of xenotransplantation study.Ovaries for were obtained private farm outside the facility.Histopathologically, multifocal to coalescing granulomatous myocarditis observed heart, characterized by infiltration lymphocytes, macrophages and multinucleated giant cells, myocardial necrosis fibrosis.Lymphoid...
Eosinophilic granuloma is a common hypersensitive inflammatory skin disease in cats, and rare dogs horses.The biopsies of 5 years old female Cocker spaniel 2 mixed dog had the clinical signs nodules with alopecia were submitted for diagnosis.Solitary papillary presented on left external ear back dog, respectively.Histopathologically, epidermis showed mild to severe hyperplasia multifocal ulceration.Small large irregular, brightly eosinophilic foci degenerating eosinophils homogeneous...
Three neonatal pigs from the same litter in a domestic farm were born with skin lesions. Grossly, multiple well-circumscribed, round papules distributed over of three piglets. Two piglets submitted for diagnosis disease. Microscopically, epidermal hyperplasia ballooning degeneration stratum spinosum keratinocytes was observed. Some contained eosinophilic intracytoplasmic inclusions and central nuclear vacuole chromatin margination. Swinepox (SWP) virus detected by polymerase chain reaction...
Adenomyosis is a nonneoplastic hyperplastic lesion, characterized by invagination of proliferating endometrial glands into myometrium. In dogs, uterine adenomyosis relatively rare and it important in Toxicologic Pathology to differentiate other non-neoplastic neoplastic lesions uterus. the present study, we report two cases female beagle dogs used for chemical toxicity test. Clinically, one out 15 months age, had vaginal bleeding 2 weeks one, 11 showed swelling vulva week. At necropsy,...
Porcine deltacoronavirus (PDCoV) has emerged as a significant issue in multiple pork-producing countries. This study isolated novel PDCoV strain, GNU-2105/KOR/2021, which caused severe diarrhea outbreak with high mortality rate among neonatal piglets South Korea. The growth properties and sialic acid dependency of the GNU-2105 strain cell culture were comparable to those 2016 domestic isolate, KNU-1607. Interestingly, phylogenetic analysis using complete genome identified 2021 demonstrated...
Min-Jung Kim, Young-Kwang Jo, Sang-chul Kang, Hyun-Ju Oh, Geon-A Erif Maha Nugraha Setyawan, Yoo-Bin Choi, Seok-Hee Lee, Hyun-il Kim and Byeong-Chun Lee. J Vet Clin 2015;32:536-9. https://doi.org/10.17555/jvc.2015.12.32.6.536
Postweaning multisystemic wasting syndrome (PMWS), which was first identified in western Canada 1991 and more recently the United States, Europe Asia, is an emerging disease pigs.Porcine circovirus type 2 (PCV-2) primary infectious viral agent causing PMWS, but full expression of may require presence other agents.It reported that there apparent synergism between PCV-2 porcine parvovirus (PPV) increasing severity clinical signs lesions PMWS.From January 2006 to May 2008, a total 154 lymph...