A5041553387- Collagen: Extraction and Characterization
- Bone Tissue Engineering Materials
- Genomics, phytochemicals, and oxidative stress
- Vitamin C and Antioxidants Research
- Glutathione Transferases and Polymorphisms
- biodegradable polymer synthesis and properties
- Protein Hydrolysis and Bioactive Peptides
- Linguistics and Cultural Studies
- Medicinal Plants and Bioactive Compounds
- Biochemical effects in animals
- MicroRNA in disease regulation
- Ottoman and Turkish Studies
- Natural Antidiabetic Agents Studies
- Heme Oxygenase-1 and Carbon Monoxide
- Cultural and Sociopolitical Studies
- Cardiac Ischemia and Reperfusion
- Mitochondrial Function and Pathology
- Diet, Metabolism, and Disease
- Sirtuins and Resveratrol in Medicine
- Antioxidants, Aging, Portulaca oleracea
- 3D Printing in Biomedical Research
- Hydrogels: synthesis, properties, applications
- Hemostasis and retained surgical items
- Menopause: Health Impacts and Treatments
- Mangiferin and Mango Extracts
Sanko University
2015-2024
Gaziantep University
2010
Istanbul University
2003-2006
Huntington’s disease (HD) is a neurodegenerative disorder characterized by progressive loss of neurons, which leads to behavioral systems and mental decline. HD linked repeat expansions cytosine, adenine, guanine in the Huntingtin (HTT) gene that give rise mutation, leading formation HTT protein product. Oxidative stress also provokes initiation progression as it misfolding results inclusion clumps together alters neurotransmission. Despite advancement field pharmaceutical sciences, current...
The objectives of this study were a) to investigate the effect targeting PANoptosome with 3,4-methylenedioxy-β-nitrostyrene (MNS) on PANoptosis in Renal ischemia-reperfussion (RIR) model b) kidney protective MNS toward RIR injury.Thirty-two rats divided into four groups randomly. assigned as Control, Sham, DMSO (dimethyl sulfoxide) and groups. group intraperitoneally given 20 mg/kg 30 minutes before reperfusion. 2% solvent that dissolves group. Left nephrectomy was performed under anesthesia...
Abstract The reconstruction of bony defects in the alveolar crest poses challenges dental practice. Guided tissue regeneration (GTR) and guided bone (GBR) procedures utilize barriers to promote prevent epithelial growth. This study focuses on evaluating antibacterial properties marine algae-polylactic acid (PLA) composite membranes compared commercially available collagen membranes. Marine algae (Corallina elongata, Galaxaura oblongata, Cystoseira compressa, Saragassum vulgare, Stypopodium...
<i>Introduction:</i> Reactive oxygen species-induced damage to DNA plays a major role in carcinogenesis. <i>Methods:</i> In order estimate the level of oxidative bladder cancer, 8-hydroxy-2′-deoxyguanosine (8-OHdG) was determined isolated from peripheral blood leukocytes healthy adults and patients with superficial transitional cell carcinoma. Patients carcinoma control individuals were similar age. this study, 8-OHdG male subjects measured by high-performance liquid...
The current study aimed to describe the fabrication of a composite patch by incorporating marine algae powders (MAPs) into poly-lactic acid (PLA) for bone tissue engineering. prepared was functionalized with co-polymer, poly (2-hydroxyethyl methacrylate-co-ethylene glycol dimethacrylate) (p(HEMA-co-EGDMA)) via initiated chemical vapor deposition (iCVD) improve its wettability and overall biocompatibility. iCVD MAP–PLA showed superior cell interaction human osteoblasts. Following surface...
In recent years much attention has been focused on the role of glutathione (GSH) and GSH-related enzymes such as peroxidase (GSH Px), reductase Red), S-transferase (GST) in inhibition free radical-induced carcinogenesis. this study, erythrocyte GSH levels activities Px, Red, GST were determined patients with colorectal tumors (n = 20, mean age 54.5 - 8.3 yr). Erythrocyte Red significantly higher tumors. Px found to be decreased patients. When classified based their clinical grading (Dukes...
The aim of the present study is to evaluate relationship total antioxidant capacity, oxidant status, oxidative stres and free sulfydryl groups in patients with diabetic nondiabetic senil cataract.The was carried out on venous blood samples from 70 subjects admitted ophtalmology clinic a research hospital. Of these, 25 were senile Type 2 cataract who using oral hypoglycemic agents or insülin. Fourty-five comprised control group. Total status (TOS), capacity (TAC) -SH levels measured sera...
Purpose: In our study, it was aimed to investigate the preventive effect of milrinone on renal damage in experimental controlled non-heart-beating donors (NHBDs) model. Materials and Methods: Sixteen rats randomly divided into 2 groups, 8 each were used. Group 1 control, group group. received 1.25 ml 0.09% NaCl intraperitoneally equivalent diluted volume. administered with 0.5 mg/kg hours before cardiac arrest. After arrest, left nephrectomy applied rats. Malondialdehyde, superoxide...
The aim of this study was to investigate how myeloperoxidase (MPO) G-463A gene polymorphism and enzyme levels varied among patients with chronic lymphocytic leukemia (CLL) multiple myeloma (MM) find the relationship between MPO gene, levels, clinical parameters. We studied sera from 40 healthy volunteers, CLL (n = 34) MM 28). In subjects homozygote GG genotype, were higher in both than control group. This difference statistically significant CLL. conclusion, genotype is found be associated...
Oxidative stress and generalized inflammatory state are features of bipolar disorders (BD). The objective this study was to compare the levels products reaction oxidative markers in patients with attention deficit/hyperactivity disorder (ADHD) determine relationship between inflammation disorders. ADHD+BD (n = 30) BD healthy controls were enrolled. A clinical evaluation measurements malondialdehyde (MDA), high sensitive C reactive protein (hsCRP) myeloperoxidase (MPO) performed. Patients...
Biodegradable collagen-based materials have been preferred as scaffolds and grafts for diverse clinical applications in density orthopedy. Besides the advantages of using such bio-originated materials, use collagen matrices increases risk infection transmission through cells or tissues graft/scaffold. In addition, solutions are not counted economically feasible approaches due to their high production cost. recent years, incorporation marine algae synthetic polymers has considered an...
The present study aims to evaluate the antioxidant effect of beta-glucan on oxidative DNA damage by comet assay.A total 19 adult females and males diagnosed with stage 3-4 colorectal cancer a control group 20 age-matched healthy subjects were enrolled in study. Blood samples participants analyzed using Comet Assay for parameters damage.Significantly increased was observed patients versus as indicated greater values tail moment, percent length. Following incubation β-glucan, substantial...
In present study, biochemical compositions (ash, lipid and protein) of five different macroalgae ((Green Macroalgae-GMA (Chaetomorpha linum Caulerpa prolifera), Red Macroalgae-RMA (Pterocladiella capi-lacea), Brown Macroalgae-BMA (Sargassum vulgare Ericaria amentacea)) Angiosperm/Seagrass (Hal-ophila stipulacea) collected from Iskenderun Bay were investigated. The differences observed between such as ash, protein species (Halophila stip-ulacea) statistically significant (p&lt;0.05)....