- Asthma and respiratory diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Advanced Chemical Sensor Technologies
- Inhalation and Respiratory Drug Delivery
- Telomeres, Telomerase, and Senescence
- Birth, Development, and Health
- Tuberculosis Research and Epidemiology
- Infective Endocarditis Diagnosis and Management
- Genetics, Aging, and Longevity in Model Organisms
- Mycobacterium research and diagnosis
- Heat shock proteins research
- Systemic Sclerosis and Related Diseases
- Respiratory and Cough-Related Research
- Autoimmune and Inflammatory Disorders Research
- Kawasaki Disease and Coronary Complications
- Hydrogen's biological and therapeutic effects
- Burn Injury Management and Outcomes
- Antibiotic Resistance in Bacteria
- Computational Drug Discovery Methods
- Phytochemicals and Antioxidant Activities
- Medical and Biological Ozone Research
- Viral Infections and Immunology Research
- Respiratory viral infections research
- High Altitude and Hypoxia
- Chemotherapy-induced cardiotoxicity and mitigation
Medical University of Lodz
2000-2016
Republican Scientific and Practical Center of Cardiology
2001
Objective: To determine whether (1) rapid consumption of 1 L apple juice increases blood antioxidant capacity, measured as ferric-reducing ability plasma (FRAP) and serum 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging activity, (2) polyphenols or fructose-induced elevation uric acid contributes to post-juice increase activity.Methods: The study involved 12 (mean age 32 ± 5 years, mean body weight 73 7 kg) healthy nonsmoking subjects. Tested subjects consumed clear then FRAP;...
Repeated nucleotide sequences combined with proteins called telomeres cover chromosome ends and dictate cells lifespan. Many factors can modify telomere length, among them are: nutrition smoking habits, physical activities socioeconomic status measured by education level. The aim of the study was to determine influence above mentioned on peripheral blood mononuclear length. Study included 28 subjects (seven male 21 female, age 18–65 years.), smokers non-smokers without any serious health...
In autoimmune inflammatory diseases, including juvenile idiopathic arthritis (JIA), which leads to joint destruction, there is an imbalance between production of reactive oxygen species (ROS) and their neutralization which, as a consequence, "oxidative stress." The aim the study was assess concentration oxidative stress markers: nitric oxide (NO), degree lipid membrane damage, total antioxidant plasma capacity in children with JIA. Thirty-four JIA were included into study. A damage (lipid...
Abstract Background Systemic sclerosis is accompanied by an influx of activated phagocytes into distal airways. These cells release H 2 O , which may evaporate from the airways surface and be detected in expired breath condensate. We tested whether patients with systemic exhale more than healthy subjects condensate levels correlate some clinical parameters. Material methods was measured fluorimetrically 27 (22 women, five men, mean age 49 ± 13·1 years) age‐ sex‐ matched controls. Results...
Background. Uraemia is accompanied by conditions favouring the rise of H2O2 activity in body fluids. This results from increased release polymorphonuclear leukocytes and decreased plasma glutathione peroxidase activity. The purpose this study was to determine if patients on chronic haemodialysis (HD) exhale more than healthy individuals, dialysis affects breath content.
Obstructive sleep apnea syndrome (OSAS) is a recognized risk factor for cardiovascular morbidity and mortality, perhaps due to causative exacerbations of systemic oxidative stress. Putative stress related numerous episodes intermittent hypoxia, may be an oxidants chief driving force in OSAS patients.We assessed the resting n-formyl-methionyl-leucyl-phenylalanine (fMLP)- induced whole blood chemiluminescence (as measure oxidant production by polymorphonuclear leukocytes monocytes), ferric...
Background Chronic renal failure (CRF) and hemodialysis (HD) accumulate an inflammatory milieu, contributing to increased systemic airway oxidative stress that may lead lung damage. Objectives This study was designed assess exhaled hydrogen peroxide (H 2 O ), function whole blood chemiluminescence in HD CRF patients healthy controls. Methods The included 59 (Polyamide S™ or Hemophan® membranes-19, cuprophane-16, hemodiafiltration-14, continuous ambulatory peritoneal dialysis-10), 16...
Infective endocarditis (IE) and surgical procedures related to cardiac surgery are accompanied by inflammatory responses that may alter production of oxidants phagocytes. This study evaluates luminol enhanced whole blood chemiluminescence (LBCL) as a measure oxidative circulating phagocytes in 26 IE patients comparison 27 matched with acquired valvular heart disease 25 healthy controls. Blood was collected the day before 3, 7, 12 21 days after valve replacement for LBCL measurement; resting...