A5041215745- GABA and Rice Research
- Phytochemicals and Antioxidant Activities
- Essential Oils and Antimicrobial Activity
- Meat and Animal Product Quality
- Plant Growth Enhancement Techniques
- Metabolomics and Mass Spectrometry Studies
- Postharvest Quality and Shelf Life Management
- Biochemical Analysis and Sensing Techniques
- Hops Chemistry and Applications
- Spectroscopy and Chemometric Analyses
- Nuts composition and effects
- Cannabis and Cannabinoid Research
- Cynara cardunculus studies
- Seed Germination and Physiology
- Botanical Research and Applications
- SARS-CoV-2 and COVID-19 Research
- Medicinal plant effects and applications
- Ginseng Biological Effects and Applications
- Vitamin C and Antioxidants Research
- Edible Oils Quality and Analysis
- Folate and B Vitamins Research
- Medicinal Plants and Bioactive Compounds
- Nanocomposite Films for Food Packaging
- Neurological diseases and metabolism
- Mycotoxins in Agriculture and Food
Sapienza University of Rome
2020-2025
Vitamin B12 (VitB12) is a micronutrient and acts as cofactor for fundamental biochemical reactions: the synthesis of succinyl-CoA from methylmalonyl-CoA biotin, methionine folic acid homocysteine. VitB12 deficiency can determine wide range diseases, including nervous system impairments. Although clinical evidence shows direct role in neuronal homeostasis, molecular mechanisms are yet to be characterized depth. Earlier investigations focused on exploring shifts resulting function coenzyme,...
The recovery of bioactive compounds from crop byproducts leads to a new perspective way waste reutilization as part the circular economy. present study aimed at an exhaustive metabolite profile characterization globe artichoke and cauliflower (leaves, stalks, florets for only) prerequisite their valorization future implementations. aqueous organic extracts was analyzed using NMR-based metabolomics approach. Free amino acids, sugars, polyols, polyphenols, amines, glucosinolates, fatty...
High consumption of fruit and vegetables has an inverse association with cardiometabolic risk factors. This study aimed to chemically characterize the hydroethanolic extract P. domestica subsp. syriaca pulp evaluate its inhibitory activity against metabolic enzymes production proinflammatory mediators. Ultra-high-performance liquid chromatography high-resolution mass spectrometry(UHPLC-HRMS) analysis showed presence hydroxycinnamic acids, flavanols, glycoside flavonols, while nuclear...
Acheta domesticus (house cricket) has been recently introduced into the official European list of novel foods, representing an alternative and sustainable food source. Up to now, chemical characterization this edible insect focused only on specific classes compounds. Here, three production batches A. powder were investigated by means a multimethodological approach based NMR, FT-ICR MS, GC-MS methodologies. The applied analytical protocol, proposed for first time in study insect, allowed us...
The chemical profile of the female inflorescence extracts from seven Cannabis sativa L. dioecious cultivars (Carmagnola, Fibranova, Eletta Campana, Antal, Tiborszallasi, Kompolti, and Tisza) was monitored at three harvesting stages (4, 14, 30 September), reaching beginning flowering to end flowering/beginning seed formation, using untargeted nuclear magnetic resonance (NMR) targeted (ultra-high-performance liquid chromatography (UHPLC) spectrophotometry) analyses. tetrahydrocannabinol...
Nine commercial hemp seed oils from different countries were studied using a multimethodological approach to obtain information about their quality and chemical composition. Due the lack of specific regulation for oils, parameters used in case olive (free acidity, peroxides number, spectrophotometer parameters) anisidine number measured compared with those reported extra virgin oil (EVOO). Free acidity showed great variability, ranging 0.4 17.24% 4.32 22.14 meqO2/kg, respectively, whereas...
The metabolite profile of fresh Goji berries from two cultivars, namely Big Lifeberry (BL) and Sweet (SL), grown in the Lazio region (Central Italy) harvested at different periods, August October, corresponding beginning end maturation, was characterized by means nuclear magnetic resonance (NMR) electrospray ionization Fourier transform ion cyclotron (ESI FT-ICR MS) methodologies. Several classes compounds such as sugars, amino acids, organic fatty polyphenols, terpenes were identified...
The metabolite profile of ten traditional apple cultivars grown in the Piedmont region (Italy) was studied by means nuclear magnetic resonance spectroscopy, identifying an overall number 36 compounds. A more complete assignment proton (1H NMR) resonances from hydroalcoholic and organic extracts with respect to literature data reported, fructose tautomeric forms, galacturonic acid, γ-aminobutyric acid (GABA), p-coumaroyl moiety, phosphatidylcholine, digalactosyldiacylglycerol. chemical each...
A multidisciplinary protocol is proposed to monitor the preservation of fresh pumpkin samples (FP) using three commercial polymeric films: made biodegradable cellophane from regenerated cellulose pulp; B corn starch, cassava and eucalyptus, C polylactic acid a polyethylene film used as reference (REF). Chemical, mechanical microbiological analyses were applied on packaging packaged at different times. After an 11-day period, NMR spectroscopy results showed sucrose increase malic decrease in...
Torpedino di Fondi (TF) is a hybrid tomato landrace developed in Sicily and recently introduced the south Lazio area along with classical San Marzano (SM) cultivar. The present study aimed at characterizing TF tomatoes both pink red ripening stages, comparing them traditional SM tomatoes. A multidisciplinary approach consisting of morphological, chemical (FT-ICR MS, NMR, HPLC, spectrophotometric methods), biological (antioxidant antifungal vitro activity) analyses was applied. Morphological...
In this study, the effect of several agronomical practices on chemical composition hemp inflorescences, a potential novel food that needs to be further studied, was observed. Here, case study inflorescences from Ferimon cultivars is discussed and submitted different (irrigation fertilizers) in years, harvested periods were analyzed by multimethodological approach. Targeted untargeted methodologies allowed cannabinoids, total phenolic content, metabolite profile antioxidant activity...
Currently, the leaves of hop plant (Humulus lupulus L.) are an unexploited and still little-investigated agricultural by-product. In our study, with aim exploring metabolome dried (Chinook cultivar), a metabolomic approach was applied using multiple analytical tools such as SPME/GC–MS, GC–MS, PTR-ToF-MS, NMR to identify secondary metabolites. The obtained results showed presence high number components belonging different chemical classes. fact, thanks multi-methodological approach, volatile...
Food reformulation is a strategy to make healthier foods by using food waste matrices that are still nutritionally valid. A shortbread cookie was reformulated replacing hazelnut skin (HS) of the Tonda Gentile Romana variety (5% and 10%) refined flour proportionally decreasing butter amount. This resulted in significant, two- five-fold, increases antioxidant capacity compared with control, 5% 10% fortified recipes, respectively. Among most important antioxidants, gallic acid, catechin,...
A fast HPLC method with fluorescence detector (FD) was developed for the determination of three tocopherols (TOCs) in milk samples from Modicana cattle breed. The ultrasound-assisted procedure optimized extraction TOCs prior to HPLC/FD analysis, reducing sample preparation time and allowing a quantification α-tocopherol, δ-tocopherol γ tocopherol. ultrasonic combines an efficient simple saponification at room temperature rapid milk. precision full analytical satisfactory recoveries spiked...
Abstract Background Cauliflower ( Brassica oleracea L.) and globe artichoke Cynara scolymus are vegetables with a high waste index mainly related to stems leaves. In this study, enzymatic hydrolysates obtained from these wastes were proposed be used as plant biostimulants. Life cycle assessment methodology was also applied evaluate environmental performances cauliflower byproducts. Results Hydrolysates (HYs) chemically biologically characterized. Amino acids, organic amines, polyols, mineral...
The health-promoting properties of blueberries are widely recognized and mainly attributed to anthocyanins. However, fruit's chemical composition includes also other components strongly depends on varieties climatic conditions. Here,
Beauvericin (BEA) is an emerging mycotoxin produced by some species of Fusarium genera that widely contaminates food and feed. Gentiana lutea a protected medicinal plant known for its antioxidant anti-inflammatory properties, which are attributed to rich content bioactive compounds. In order evaluate the beneficial effects G. flower against BEA cytotoxicity, aim this study changes in protein expression after Jurkat cell exposure through proteomics approach. To carry out experiment, cells...