- Marine Sponges and Natural Products
- Marine Biology and Environmental Chemistry
- Microbial Natural Products and Biosynthesis
- Synthesis and Biological Activity
- Traditional and Medicinal Uses of Annonaceae
- Microplastics and Plastic Pollution
- Environmental Chemistry and Analysis
- Algal biology and biofuel production
- Aquaculture Nutrition and Growth
- Marine Bivalve and Aquaculture Studies
- Protein Hydrolysis and Bioactive Peptides
- Identification and Quantification in Food
- Marine and coastal plant biology
- Adsorption and biosorption for pollutant removal
- Physiological and biochemical adaptations
- Echinoderm biology and ecology
- Seaweed-derived Bioactive Compounds
- Phytochemical compounds biological activities
- Ionic liquids properties and applications
- Analytical chemistry methods development
- Extraction and Separation Processes
- Macrophage Migration Inhibitory Factor
- Bioactive Compounds and Antitumor Agents
- Fish Biology and Ecology Studies
- Antimicrobial agents and applications
Universiti Malaysia Terengganu
2017-2024
Seaweeds or macroalgae are the primary producers of an oceanic food source, widely distributed across globe and known for their excellent defensive properties against numerous biotic abiotic factors.These traits come from secondary metabolites that act as protective barriers pathogens harmful organisms where among these compounds some have been found possessing antifouling characteristic.In this study, Dictyota dichotoma Sargassum granuliferum collected Pulau Nunuyan Laut, Sabah, Malaysia,...
Biofouling is defined as the excessive colonization process of epibiotic organisms, ranging from microfoulers to macrofoulers, on any submerged surface in water. Previous research has attempted explore antifouling activity bacterial isolates due biofouling problems occurring worldwide. One solution inhibit early stage fouling using secondary metabolites produced by marine bacteria. This study aims determine activities microorganism P. aeruginosa and characterize bacteria isolated a potential...
Sponges are sessile marine animals under the phylum Porifera. Conventionally, identification of sponges is based on two criteria: Morphology (shape, colour, surface characteristics and consistency) macro-morphology (spicules, sponging fibres their arrangement). This technique sometimes unreliable due to plasticity sponges’ characteristics, which causes misidentification. We utilized universal barcode COI primers identify in this study. study shows results that have been collected through...
Antifouling paint was introduced and utilized as a control to prevent the problem of biofouling. The Methanolic Crude Extract (MCE) Essential Oil (EO) were extracted from Melaleuca cajuputi. Gas Chromatography-Mass Spectrometry (GC-MS) used determine metabolite profiles. An antibacterial assay conducted via disc diffusion technique an antifouling MCE EO M. cajuputi investigated using crystal violet painted steel panels incorporating EO. Painted immersed in aquarium measure antibiofilm...
Marine resources such as marine invertebrates and mangrove plants favor the production of secondary metabolites that exhibit antifouling properties. These natural-derived compounds are considered environmentally friendly compared to synthetic with similar activity technological applications. The current study was conducted determine properties Diadema setosum (DS) Sonneratia lanceolata (SL) crude extracts their incorporated paints, in addition identification involved. Both were tested...
Texture is an important sensory attribute for overall quality and consumer acceptance of prawns. However, texture affected during cold storage due to the proteolytic activity endogenous proteases, resulting in poor a short shelf life. The objective this study determine inhibitory effects Annona muricata leaves extract (AMLE) (0, 3, 10 20%) on trypsin, cathepsin B collagenase activities extracted from cephalothorax Macrobrachium rosenbergii. In addition, textural changes M. rosenbergii 20...
Cancer is an uncontrolled multiplication of cells. The desire efficacy and severe toxicity current anticancer drugs urge exploring investigating a better alternative to existing chemotherapeutics. Natural products marine origin are excellent sources potential new enhanced biological activities.
Marine sponges are primitive sessile animals that rich sources of biologically active compounds. This paper aimed to assess the in-vitro biological activity marine from Theonella and Haliclona genera collected Bidong Island, Terengganu, Malaysia. Biological activities such as antibacterial (discs diffusion assay), antioxidant (DPPH free-radical scavenging cytotoxicity (against cancerous HeLa, MCF-7, HepG-2 cell lines normal line Vero) were evaluated using MTT assay. The bioassays done on...
Natural products play a crucial role in drug discovery. In the last decade, advent of marine natural product research has produced remarkable number compounds, particularly those isolated from sponges, with broad range activities for treatment human and animal diseases. this study, five known alkaloids namely aaptamine (1), 9-demethylaaptamine (2), 4- N-methylaaptamine (3), 9-methoxyaaptamine (4), 9-demethyloxyaaptamine (5), an uncommon amide sponge, 4-hydroxybenzamide (6) 3 β,5α-cholesterol...
Mangrove plants are endowed with various biologically active compounds which have potent antibacterial and antioxidant properties. In present study, a bioactivity-guided fractionation for metabolites from the twigs of Avicennia officinalis collected Kuala Selangor Nature Park, Selangor, Malaysia gave 13 major fractions. The activity A. fractions using well-diffusion showed strong selectivity on Gram-positive bacteria (Staphylococcus epidermidis, S. aureus Bacillus subtilis) minimum...
This present study aimed to investigate the effects of Gracilaria changii (Red seaweed) extract and its fraction on scavenger receptor class B type I (SR-BI) gene expressions. In vitro studies activity G. against therapeutic target for hypocholesterolemia were conducted using high-density lipoprotein (HDL) SR-BI via luciferase assay in HepG2 cells. current study, methanol crude (MCE) Fraction-2 showed highest expression levels increased mRNA compared negative control. Metabolite profiling...
Lipids and fatty acids in microalgae depend on cultivation variables, including phosphate concentrations. Until now, the effect of low culture media is still limited Thalassiosira weissflogii. This study determines impact concentrations biomass, lipids, acids, molecular responses T. weissflogii optimum were cultured 0.064, 0.129, 0.193, 0.258 µM A concentration 0.064 was recorded as highest biomass (27.47 g/L), total lipids (28.36%), eicosapentaenoic (EPA, 6.83 mg/g). The transcriptome...
Biofilm, intricate microbial communities adhering to submerged surface, pose a significant challenge across various sectors. Conventional approaches relying on harsh chemical or mechanical removal have drawback. Marine organisms like sponges, with their diverse secondary metabolites, offer promising avenue for developing sustainable solutions. This study investigated the antibiofilm potential of crude extracts from four marine sponges ( Stylissa carteri , Haliclona amboinensis Hymeniacidon...