Industrial enzymes are important for various biotechnological applications. Currently, the diversity of industrial enzymes-producing marine bacteria from Malaysia remains mostly unknown. This study investigated enzyme-producing culture collections at Institute Marine Biotechnology, Universiti Terengganu. Out 200 bacterial isolates revived, 163 isolate were successfully growth. produced with total scoring higher than four selected molecular identification using 16S rDNA. About 161 secreted...

Biofouling is defined as the excessive colonization process of epibiotic organisms, ranging from microfoulers to macrofoulers, on any submerged surface in water. Previous research has attempted explore antifouling activity bacterial isolates due biofouling problems occurring worldwide. One solution inhibit early stage fouling using secondary metabolites produced by marine bacteria. This study aims determine activities microorganism P. aeruginosa and characterize bacteria isolated a potential...

In vitro and in vivo studies of the activity Phaleria macrocarpa Boerl (Thymelaeaceae) leaves against therapeutic target for hypercholesterolemia were done using HDL receptor (SR-BI) hypercholesterolemia-induced Sprague Dawley rats. The study showed that active fraction (CF6) obtained from ethyl acetate extract (EMD) its component 2',6',4-trihydroxy-4'-methoxybenzophenone increased SR-BI expression by 95% 60%, respectively. has proven effect EMD at 0.5 g/kgbw dosage reducing total...

Sponges are sessile marine animals under the phylum Porifera. Conventionally, identification of sponges is based on two criteria: Morphology (shape, colour, surface characteristics and consistency) macro-morphology (spicules, sponging fibres their arrangement). This technique sometimes unreliable due to plasticity sponges’ characteristics, which causes misidentification. We utilized universal barcode COI primers identify in this study. study shows results that have been collected through...

Coral reefs in Southeast Asia are becoming progressively degraded due to the natural and anthropogenic disturbances which lead poor water quality threatening reefs' health.Coral disease is one of threats coral worldwide but research on relatively scarce especially bacterial community associated with disease.The destructive black band (BBD) can be found widely southern region South China Sea, Malaysia.This study aims compare microbial communities healthy BBD-infected tissue from two different...

The effects of Hydnophytum formicarum ethanolic extract towards lymphocyte, vero and T47d cells proliferation in vitroDavid Darwis, Triana Hertiani, Ediati Samito

Marine resources such as marine invertebrates and mangrove plants favor the production of secondary metabolites that exhibit antifouling properties. These natural-derived compounds are considered environmentally friendly compared to synthetic with similar activity technological applications. The current study was conducted determine properties Diadema setosum (DS) Sonneratia lanceolata (SL) crude extracts their incorporated paints, in addition identification involved. Both were tested...

This study delves into the enzymatic and antimicrobial capabilities of actinomycetes isolated from Setiu Wetland mangrove in Terengganu, Malaysia. A total eighteen actinomycete bacteria were characterized site. These isolates underwent assessments targeting a representative range Gram-positive bacteria, Gram-negative fungus employed for testing. The results evaluations demonstrated pronounced effectiveness majority against bacterial strains. Intriguingly, notable observation was inhibition...

Cancer is an uncontrolled multiplication of cells. The desire efficacy and severe toxicity current anticancer drugs urge exploring investigating a better alternative to existing chemotherapeutics. Natural products marine origin are excellent sources potential new enhanced biological activities.

Rhamnolipid (RL), the major component of biosurfactant is commonly produced via bacterial fermentation from selected carbon sources.Biosynthesis RL initiated by nitrogen limitation and presence excess source.RL completely biodegradable non-toxic.Applications include production fine chemicals, enhancement biodegradation, food industries pharmaceutical products.In this study, efforts were taken to biosynthesize using Pseudomonas aeruginosa UMTKB-5 isolated marine sediment.The bacterium was fed...

Marine sponges are primitive sessile animals that rich sources of biologically active compounds. This paper aimed to assess the in-vitro biological activity marine from Theonella and Haliclona genera collected Bidong Island, Terengganu, Malaysia. Biological activities such as antibacterial (discs diffusion assay), antioxidant (DPPH free-radical scavenging cytotoxicity (against cancerous HeLa, MCF-7, HepG-2 cell lines normal line Vero) were evaluated using MTT assay. The bioassays done on...

Natural products play a crucial role in drug discovery. In the last decade, advent of marine natural product research has produced remarkable number compounds, particularly those isolated from sponges, with broad range activities for treatment human and animal diseases. this study, five known alkaloids namely aaptamine (1), 9-demethylaaptamine (2), 4- N-methylaaptamine (3), 9-methoxyaaptamine (4), 9-demethyloxyaaptamine (5), an uncommon amide sponge, 4-hydroxybenzamide (6) 3 β,5α-cholesterol...

Objective: This study aimed to investigate the anti-inflammatory activity of methanol extract and fractions bacteria associated with sponge (Haliclona amboinensis) evaluate their effect in reducing NO production inhibiting cyclooxygenase-1 (COX-1), cyclooxgenase-2 (COX-2) secretory phospholipase A2 (sPLA2) activity.Methods: All bacterial isolates were cultured supernatants collected for extraction secondary metabolites using diaion HP-20 obtain extracts. Evaluation cytotoxicity property was...

In recent years, high numbers of research focusing on secondary metabolites produced by terrestrial bacteria towards anti-inflammatory properties but, minority them used associated to marine organism. this study, 25 colonies were isolated from sponge Theonella sp. which was collected Bidong Island, Terengganu. Cytotoxicity and activity these studied using macrophage cell lines: RAW 264.7 .Macrophage plays a role in mammalian immune system providing defense against foreign harmful substance...

Serratia marcescens subsp. sakuensis strain K27 was isolated from sponge (Haliclona amboinensis). The genome of this consists 5,325,727 bp, with 5,140 open reading frames (ORFs), 3 rRNAs, and 67 tRNAs. It contains genes for the production amylases, lipases, proteases. Gene clusters biosynthesis nonribosomal peptides thiopeptide were also identified.

An investigation was conducted on cabbage extract (Brassica oleracea) to observe its function as green antifouling agent in alkyd undercoat for mild steel seawater.Cabbage shows 43.6% of inhibition efficiency towards Pseudomonas aeruginosa bacteria at 15.525 g/mL concentration.FTIR analysis the complexation between paint and where peak OH, C-H C=O have shifted indicating chain scission resin polymer backbone with extract.Weight gained reveals that coated incorporated had reduced fouling...

This present study focused on the extraction of HAp from fish scale waste using alkaline heat treatment sintered at different sintering tem-perature (high range) between 300° C to 1000°C. White powder hydroxyapatite was characterized in term morphology, surface chemistry and crystallinity structure Scanning Electron Microscopy, Fourier transform infrared spectroscopy (FTIR) X-ray Diffraction (XRD), respectively. Analysis XRD shows that FSHAp-1000 has good sharp peak indicating for high...

Mortality• Life expectancy for the U.S. population in 2015 was 78.8 years, a decrease of 0.1 year from 2014.• The age-adjusted death rate increased 1.2% 724.6 deaths per 100,000 standard 2014 to 733.1 2015.• 10 leading causes remained same as 2014.Age-adjusted rates eight and decreased one.• infant mortality 589.5 live births not significantly different rate.• 2014, although two exchanged ranks.This report presents final data on by demographic medical characteristics.These provide...

Sponges together with associated bacteria form complex holobionts governed by various relationships established between the partners. Molecules of communication may participate in homeostasis these biological associations. Bacteria produce N-acyl homoserine lactones to communicate. In present study, we characterized 102 cultivable isolated from sponge Suberites domuncula at genus level and described their production AHLs during 96 h culture a Marine Broth medium. The presence was monitored...

Marine sponges are acknowledged as bacterial hotspots in the oceanic biome. Aquatic bacteria being investigated comprehensively for bioactive complexes and secondary metabolites. Cultivable associated with different species of sea South China Sea waters adjacent to Bidong Island, Terengganu were identified. Molecular identification was accomplished using 16S rRNA gene cloning sequencing. Fourteen identified their phylogenetic relationships analysed by constructing a neighbour-joining tree...

<title>Abstract</title> One of the most exciting alternatives to dangerous paints based on heavy metals is development coatings that act as natural anti-settlement agents and prevent fouling by utilising active ingredients found in seaweed. This why understanding field's extraordinary growth—which encompasses a wide range topics like marine fouling, anti-biofilm, anti-fouling, future bioprospecting, coating general—requires evaluating current body research seaweed's antifouling. For this...