A5024500859- Computational Drug Discovery Methods
- Cholesterol and Lipid Metabolism
- Peroxisome Proliferator-Activated Receptors
- Lipoproteins and Cardiovascular Health
- Protein Kinase Regulation and GTPase Signaling
- Marine Sponges and Natural Products
- Plant biochemistry and biosynthesis
- Cellular transport and secretion
- Signaling Pathways in Disease
Universiti Malaysia Terengganu
2021-2022
Mortality• Life expectancy for the U.S. population in 2015 was 78.8 years, a decrease of 0.1 year from 2014.• The age-adjusted death rate increased 1.2% 724.6 deaths per 100,000 standard 2014 to 733.1 2015.• 10 leading causes remained same as 2014.Age-adjusted rates eight and decreased one.• infant mortality 589.5 live births not significantly different rate.• 2014, although two exchanged ranks.This report presents final data on by demographic medical characteristics.These provide...
A constantly elevated level of low-density lipoprotein cholesterol (LDL-C) is mainly associated with the development atherosclerosis. The use statins as a treatment for reducing plasma LDL-C levels has led, in some cases, to adverse side effects, including decrease hepatic LDL receptor (LDLR), responsible uptake circulating LDL-C. Proprotein convertase subtilisin/kexin type 9 (PCSK9) an enzyme directing LDLR–LDL-C complex lysosomal degradation upon transport into cells, preventing recycling...
Acaudina molpadioides has been long used as traditional medicinal resources and reported to demonstrate various important bioactivities such anticoagulation, antithrombosis, anti-hyperglycemia anticancer. However, its lipid lowering activity is yet be fully explored. Proprotein convertase subtilisin/kexin type 9 (PCSK9) an enzyme that enhances the lysosomal degradation of hepatic low density lipoprotein receptor (LDLR) resulting in excessive accumulation plasma levels LDL-cholesterols...