- Cervical Cancer and HPV Research
- Hepatitis B Virus Studies
- Global Cancer Incidence and Screening
- Reproductive tract infections research
- Antibiotic Use and Resistance
- Antibiotic Resistance in Bacteria
- Gut microbiota and health
- SARS-CoV-2 and COVID-19 Research
- COVID-19 diagnosis using AI
- COVID-19 epidemiological studies
- Child Nutrition and Water Access
- COVID-19 and Mental Health
- Gastrointestinal disorders and treatments
- Urinary Tract Infections Management
- HIV Research and Treatment
- Food Security and Health in Diverse Populations
- Pharmaceutical and Antibiotic Environmental Impacts
- Viral Infections and Outbreaks Research
- Diet and metabolism studies
- Biosensors and Analytical Detection
- Infections and bacterial resistance
- SARS-CoV-2 detection and testing
- Vaccine Coverage and Hesitancy
- Helicobacter pylori-related gastroenterology studies
- Molecular Biology Techniques and Applications
Addis Ababa University
2016-2024
Martin Luther University Halle-Wittenberg
2022-2024
Wollo University
2017
Introduction In sub-Saharan Africa foodborne disease and outbreaks are frequently ascribed to poor personal hygiene of street food vendors handlers in establishments. Evidence on the level practices safety measures among is required for proper planning implementation targeted interventions. this study, we aimed determine establishments Dessie Town, Ethiopia. Method A community-based cross-sectional study was performed town, Ethiopia from December 2013 June 2014. Data were collected using a...
The COVID-19 pandemic is impacting the global community in many ways. Combating requires a coordinated effort through engaging public and service providers preventive measures. government of Ethiopia had already announced prevention guidelines for public. However, there scarcity evidence-based data on knowledge, attitude, practice (KAP) response regarding COVID-19.This study aimed to assess KAP providers' preparedness towards Addis Ababa, Ethiopia.A community-based cross-sectional was...
Abstract Background Cervical cancer is the fourth most common among women worldwide. Sub- Saharan Africa has a high incidence, prevalence and mortality due to shortage underutilization of screening facilities. This study aims assess knowledge attitude towards cervical its prevention, as well practice screening. Methods cross-sectional community- based was conducted in Butajira, Ethiopia February 2018. Systematic cluster randomized sampling used select households from which targeted age group...
Although high-risk human papillomavirus infection is a well-established risk factor for cervical cancer, other co-factors within the local microenvironment may play an important role in development of cancer. The current study aimed to characterize cervicovaginal microbiota women with premalignant dysplasia or invasive cancer compared that healthy women. comprised 120 Ethiopian (60 patients who had not received any treatment, 25 dysplasia, and 35 women). Cervicovaginal specimens were...
Abstract In Ethiopia, the standard method of cervical cancer screening is using Visual Inspection with Acetic Acid (VIA). Self-collection–based human papillomavirus (HPV) testing assumed to improve uptake screening, especially for hard reach populations. We investigated whether HPV DNA self-collection samples would be associated increased and adherence procedures at population level compared VIA within defined rural in Ethiopia. A total 22 clusters (comprising 2,356 women ages 30–49 years)...
Klebsiella pneumoniae poses an urgent public health threat, causing nosocomial outbreaks in different continents. It has been observed to develop resistance antimicrobials more easily than most bacteria. These days, multidrug-resistant strains are being increasingly reported from countries. However, studies on the surveillance of very rare Ethiopia. This study aimed determine antimicrobial patterns and magnitude MDR K. isolates patients attending or admitted Tikur Anbessa Specialized...
Social, economic, and cultural factors have been associated with the level of participation in cervical cancer screening programs. This study identified nonparticipation screening, as well reasons for not attending, context a population-based, cluster-randomized trial Ethiopia. A total 2,356 women aged 30 to 49 years 22 clusters were invited receive one two approaches, namely human papillomavirus (HPV) self-sampling or visual inspection acetic acid (VIA). Participants nonparticipants...
Background . Bacterial sepsis is a major cause of illness in human immunodeficiency virus infected patients. There scarce evidence about among HIV patients Ethiopia. This study aimed to determine the etiologic agents bacterial and their antibiotic susceptibility patterns Methods A cross-sectional was carried out from March 1 May 2, 2013. One hundred with suspected having were included. Sociodemographic data collected by interview blood sample aseptically participants. All cultures incubated...
Background The World Health Organization has declared that infection with SARS-CoV-2 is a pandemic. Experiences SARS in 2003 and have shown health professionals are at higher risk of contracting COVID-19. Hence, it been recommended aperiodic wide-scale assessment the knowledge preparedness regarding current COVID-19 pandemic critical. Objectives This study aimed to assess among selected hospitals Addis Ababa, Ethiopia. Methods A facility-based cross-sectional was conducted from last week...
Abstract Background Anti-SARS-CoV-2 antibody tests are being increasingly used for sero-epidemiological purposes to provide better understanding of the extent infection in community, and monitoring progression COVID-19 epidemic. We conducted sero-prevalence study estimate prior with SARS-CoV-2 Addis Ababa. Methods A cross-sectional was done from April 23 28, 2020 among 301 randomly selected residents Ababa; no known history contact confirmed person. Interviews on socio demographic...
In Ethiopia, cervical cancer is the second leading cause of morbidity and mortality from all cancers in women. Persistent infection with human papillomaviruses (HPV) plays a key role development intraepithelial neoplasia invasive cancer. To establish baseline data on population-based prevalence HPV genotype distribution, we investigated epidemiology among rural This study was conducted women aged 30-49 years Butajira, south-central Ethiopia. A total 893 samples were tested 1020 screened...
Background Infections caused by Klebsiella pneumoniae have been difficult to control because of the worldwide emergence carbapenem-resistant isolates mainly due carbapenemase production. Information regarding carbapenemase-producing K . is still scarce in Ethiopia. Therefore, current study aimed determine prevalence and assess occurrence bla NDM KPC genes Methods A cross-sectional was conducted from September 2018 February 2019 at Tikur Anbessa Specialized Hospital, Addis Ababa, total 132...
Primary HPV testing and triage of HPV-positive women is an effective cervical cancer screening strategy. Such a multi-visit algorithm also promising for community-based in resource-poor communities, provided robust tracking system place. A campaign was conducted rural community Ethiopia. All aged 25-65 years were offered genital self-sampling using the Evalyn Brush®. Samples HPV-DNA-tested at central laboratory. Key indicators captured on tablet computers linked by cloud-based information...
Background: Although blood transfusion is one of the known therapeutic interventions that cuts across a number clinical disciplines. It necessary to test all intending donors for HIV infection before donation. The aim this study was determine prevalence among at Dessie Blood Bank, Northeast Ethiopia.Methods: A retrospective conducted in Bank through year 2008- 2012. Sera from were tested detection Anti by using 4th generation ELISA. Data abstracted records and analyzed Microsoft Excel...
Background. <i>Helicobacter pylori (H. pylori)</i> is recognized as a major human pathogen. Clinical symptoms associated with <i>H. pylori</i> infection have been reported in patients immunodeficiency virus (HIV). A high, normal, and lower sero - prevalence of HIV positive than negative controls was found different studies. The aim this study to assess the determine impact CD4 cell count St. Paul's General Specialized Hospital Addis Ababa, Ethiopia. Methods. comparative cross sectional...
When faced with a public health problem such as the COVID-19 pandemic, devising test an accurate and rapid diagnostic capacity is critical to contain disease. We compared performance of antigen in comparison reference method, namely real-time polymerase chain reaction (RT-PCR) assay.
<title>Abstract</title> Background Screenings for cervical cancer are rare in developing countries due to several barriers, the major being convenience and privacy. Thus, there was a need conduct study identify ways overcome barriers related screening participation. This rapid ethnographic assessment aimed explore respectful ethical engagement with research participants their communities cluster randomized trial that compared different strategies at community level Ethiopia. Methods...
Although cancer incidence and mortality are rising in Ethiopia, lay health professional perceptions of the disease remain limited.
Abstract Background: Cervical cancer (CC) remains a leading cause of morbidity and mortality all cancers among women residing in low-income countries, including Ethiopia. In Ethiopia, although the standard method CC screening is using Visual Inspection with Acetic Acid (VIA), service accessibility limited uptake by eligible very low. Self-sampling for human papillomavirus (HPV) DNA testing might improve targeted screening, especially hard-to-reach population We investigated whether...
Background: Food handlers (individuals engaged in food preparation, transport and provision) are implicated the transmission of foodborne diseases if appropriate hygienic practices not maintained. Hence, this study aimed to determine prevalence intestinal parasites bacteria among Dessie town, Ethiopia. Methods: A community based cross-sectional was conducted asymptomatic handlers. Stool microscopy culture performed on 135 enteric bacterial pathogens. Antimicrobial susceptibility pattern...
High-risk Human Papillomavirus (HPV) is the most important cause of cervical cancer. The highest burden disease seen in Low- and Low-Middle-Income Countries (LMIC). Several new HPV screening assays have been developed for high-risk (hr-HPV) testing. We compared performance adequacy three genotyping on samples from a population rural women south-central Ethiopia.