A5101912839- Cervical Cancer and HPV Research
- Molecular Biology Techniques and Applications
- Hepatitis B Virus Studies
- Reproductive tract infections research
- Genital Health and Disease
- Viral Infections and Vectors
- Animal Virus Infections Studies
Freie Universität Berlin
2019-2020
Humboldt-Universität zu Berlin
2019-2020
Charité - Universitätsmedizin Berlin
2018-2020
Introduction This population-based study aimed to fill the knowledge gap on Human Papillomavirus (HPV) prevalence and associated sociodemographic risk factors of general population in North Tongu District, Ghana. These results are needed guide cervical cancer prevention efforts, as leading type female cancers. Methods A cross-sectional including 2002 women Ghana investigated HPV factors. Women were recruited by geographical distribution through local community-based health system samples...
Primary HPV testing and triage of HPV-positive women is an effective cervical cancer screening strategy. Such a multi-visit algorithm also promising for community-based in resource-poor communities, provided robust tracking system place. A campaign was conducted rural community Ethiopia. All aged 25-65 years were offered genital self-sampling using the Evalyn Brush®. Samples HPV-DNA-tested at central laboratory. Key indicators captured on tablet computers linked by cloud-based information...
HPV DNA Array is an E1-targeting PCR genotyping test, with capability of distinguishing 18 high-risk (16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 73, 82) and 11 low-risk types (6, 11, 40, 42, 44, 54, 67, 69, 70, 85, 97). uses multiplex for E1-gene sequence amplification. The amplicons are detected genotyped by reverse hybridization to immobilized probes spotted as triplets in single 96 well-plate wells read AID ELISPOT reader. Aim the study was evaluate clinical...
<b><i>Background:</i></b> Cervical cancer is caused by a persistent infection of human papillomavirus (HPV). Therefore, tests which detect the carcinogenic virus can be used for cervical screening. <b><i>Objective:</i></b> This first evaluation HPV DNA Array (AID Diagnostika, Strassberg, Germany), an E1-based genotyping polymerase chain reaction (PCR) test identification 29 types (6, 11, 16, 18, 26, 31, 33, 35, 39, 40, 42, 44, 45, 51, 52, 53,...
Human papillomavirus (HPV) detection is used for screening of cervical cancer and genotype-specific persistence has shown to be mandatory dysplasia development. Aim this study was evaluate the clinical performance HPV DNA Array intraepithelial neoplasia 2+ (CIN2+) lesion detection. a polymerase chain reaction-based assay that targets E1 sequences 29 types (6, 11, 16, 18, 26, 31, 33, 35, 39, 40, 42, 44, 45, 51, 52, 53, 54, 56, 58, 59, 66, 67, 68, 69, 70, 73, 82, 85, 97). The evaluation...
Cervical cancer, caused by persistent HPV infection, is a highly preventable disease. DNA Array an E1-targeting PCR genotyping test, with capability of distinguishing 18 high-risk (16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 73, 82) and 11 low-risk types (6, 11, 40, 42, 44, 54, 67, 69, 70, 85, 97). Aim the study was to evaluate clinical performance assay against internationally accepted Cobas 4800 (Roche).