A5031501991- Frailty in Older Adults
- Health disparities and outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Global Health Care Issues
- Aging and Gerontology Research
- Treatment of Major Depression
- Child Abuse and Trauma
- Employment and Welfare Studies
- Nutrition and Health in Aging
- Chronic Disease Management Strategies
- Attention Deficit Hyperactivity Disorder
- Psychiatric care and mental health services
- Geriatric Care and Nursing Homes
- Retirement, Disability, and Employment
- Prenatal Substance Exposure Effects
- Migration, Health and Trauma
- Health and Medical Studies
- Neurological and metabolic disorders
- Alcoholism and Thiamine Deficiency
- Intensive Care Unit Cognitive Disorders
- Maternal Mental Health During Pregnancy and Postpartum
- Health and Well-being Studies
- Homelessness and Social Issues
- Blood Pressure and Hypertension Studies
- Mental Health and Psychiatry
University Medical Center Groningen
2021-2025
University of Groningen
2021-2025
GGZ inGeest
2016-2019
Cancer Research And Biostatistics
2019
Amsterdam UMC Location Vrije Universiteit Amsterdam
2016-2019
Amsterdam Public Health
2016
Abstract The aim of this study was to investigate trends in frailty and its relationship with mortality among older adults aged 64–84 years across a period 21 years. We used data from 1995 2016 the Longitudinal Aging Study Amsterdam. A total 7,742 observations 2,874 respondents same age range (64–84 years) 6 measurement waves were included. Frailty measured 32-item index, cutpoint ≥0.25 indicate frailty. outcome measure 4-year mortality. Generalized estimating equation analyses showed that...
Abstract Background To examine the mortality risk of current and life-time depressive as well anxiety disorders, whether this is moderated by sex or age, can be explained lifestyle and/or somatic health status. Methods A cohort study (Lifelines) including 141,377 participants (18–93 years) which were followed-up regarding for 8.6 years (range 3.0–13.7). Baseline disorders according to Diagnostic Statistical Manual Mental Disorders, fourth edition criteria assessed with Mini International...
Abstract Background Studying secular trends in the exposure to risk and protective factors of depression whether these are associated with prevalence is important estimate future healthcare demands identify targets for prevention. Methods Three birth cohorts 55–64-year olds from population-based Longitudinal Aging Study Amsterdam were examined using identical methods 1992 ( n = 944), 2002 964) 2012 957). A two-stage screening design was used subthreshold (SUBD) major depressive disorder...
Subthreshold depression (SUBD) in later life is common and important as prodromal state prominent risk factor the development of major depressive disorder (MDD). Indicated prevention can reduce incidence MDD among people with SUBD substantially, but needs to be targeted those that are truly at developing MDD.N = 341 eligible participants were included from first (1992/1993), second (1995/1996) third (1998/1999) cycle Longitudinal Aging Study Amsterdam (LASA) by using a two-stage screening...
Polypharmacy and late-life depression often congregate in the geriatric population. The primary objective is to identify determinants of polypharmacy patients with depression, second examine relation various clinical phenotypes its course.A longitudinal observational study using data Netherlands Study Depression Older persons (NESDO) including 375 ≥ 60 years 132 non-depressed comparisons. Linear logistic regression were used analyze both (dichotomous: ≥5 medications) number prescribed drugs...
Abstract Background The frailty index (FI) is a well-recognized measurement for risk stratification in older people. Among middle-aged and people, we examined the prospective association between FI mortality as well its course over time relation to multimorbidity specific disease clusters. Methods A was constructed based on either 64 (baseline only) or 35 health deficits follow-up) among people aged ≥ 40 years who participated LifeLines, population-based cohort living Northern Netherlands....
Abstract Introduction Depressive disorder has been conceptualised as a condition of accelerated biological ageing. We operationalised frailty index (FI) marker for ageing aimed to explore the bidirectional, longitudinal association between and either depressive symptoms or disorder. Methods A cohort study with 6‐year follow‐up including 377 older (≥60 years) outpatients DSM‐IV‐defined 132 never‐depressed controls. Site visits at baseline, 2 were conducted included CIDI 2.0 assess relevant...
Child abuse is a major global burden with an enduring negative impact on mental and physical health. A history of child consistently associated worse cognitive performance among adults; data in older age groups are inconclusive. Since affective symptoms functioning interrelated persons, synergistic effect can be assumed patients who also have suffered from abuse. This study examines the association between such patients.Cross-sectional were collected 'Routine Outcome Monitoring for Geriatric...
Frailty is an important concept for risk stratification in clinical practice, but it hardly acknowledged at all mental healthcare settings. This paper aims to assess the impact of frailty on course depression and anxiety, these affective disorders frailty.
Abstract Background The deficit accumulation method considers the ageing process underlying frailty as a random of health deficits. Objective Although Adverse Childhood Experiences (ACE) have consistently been associated with onset mental disorders and somatic diseases during adolescence midlife, it remains unknown whether ACE still exert detrimental effects in late life. Therefore, we examined cross-sectionally prospectively association between among community-dwelling older people. Design...
Frailty marks an increased risk for adverse health outcomes. Since childhood trauma is associated with the onset of physical and mental diseases during lifespan, we examined link between multidimensional frailty. A cross-sectional study embedded in a clinical cohort (ROM-GPS) older (≥60 years) patients (n=182) unipolar depressive-, anxiety- and/or somatic symptom disorder according to DSM-criteria referred specialized geriatric care. was assessed Tilburg Indicator (TFI), comprising physical,...
Childhood trauma (CT) is associated with unhealthy lifestyle in adulthood. However, an in-depth exploration of how CT relates to multiple behaviors remains inconclusive. This study included 2968 adults from the Netherlands Study Depression and Anxiety. We examined associations between retrospectively reported CT, its severity, types seven a cumulative index. Results showed that was positively smoking, illicit drug use, social inactivity, sleep deprivation, excessive weight gain (β =...
Abstract Aims Studying birth-cohort differences in depression incidence and their explanatory factors may provide insight into the aetiology of could help to optimise prevention strategies reduce worldwide burden depression. Methods Data were used from Longitudinal Aging Study Amsterdam, a nationally representative study among community dwelling older adults Netherlands. Cohort over 10-year-period (score ⩾16 on Center for Epidemiologic Studies Depression scale) tested using...
1891 participants (M age =71.1 ± 9.1 years), 289 (15.3%) had a depressed mood.The neighbourhood livability was poor for 154 (8.1%) participants.A trend positive association between depressive symptoms and found (B=1.15;p=0.06).After adjustment individual socio-economic status, this not statistically significant.A domain score on safety remained to be significantly associated with less (B=-0.02;p=0.01).Especially, could addressed improve mental health in older adults.