A5076480519- Wound Healing and Treatments
- Diagnosis and Treatment of Venous Diseases
- Pressure Ulcer Prevention and Management
- Autoimmune Bullous Skin Diseases
- Diabetes Management and Research
- Autoimmune and Inflammatory Disorders
- Oral Health Pathology and Treatment
- Dermatologic Treatments and Research
- Diabetes and associated disorders
- Nail Diseases and Treatments
- Public Administration and Political Analysis
- Skin Diseases and Diabetes
- Diabetic Foot Ulcer Assessment and Management
- Urticaria and Related Conditions
- Systemic Sclerosis and Related Diseases
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Pancreatic function and diabetes
- Systemic Lupus Erythematosus Research
- Inflammatory Myopathies and Dermatomyositis
- Mobile Health and mHealth Applications
- Tendon Structure and Treatment
- Reproductive Health and Technologies
- Dermatology and Skin Diseases
- Medical Practices and Rehabilitation
- Populism, Right-Wing Movements
Klinikum Esslingen
2022-2024
University of British Columbia
2019-2024
AGCO (Germany)
2022
Universitätsklinikum Erlangen
2012-2021
Friedrich-Alexander-Universität Erlangen-Nürnberg
2013-2021
University of Würzburg
2018-2021
Praxis für Humangenetik
2020
Women's Health Research Institute
2019
Roswell Park Comprehensive Cancer Center
2016
University Hospital Leipzig
2004-2013
Pyoderma gangrenosum (PG) is a rarely diagnosed ulcerative neutrophilic dermatosis with unknown origin that has been poorly characterized in clinical studies so far. Consequently there have significant discussions about its associated factors and comorbidities. The aim of our multicenter study was to analyze current data from patients dermatologic wound care centers Germany order describe comorbidities PG.Retrospective investigation PG Germany.We received 259 20 different Germany. Of these...
Chronic recalcitrant dermatophytoses, due to Trichophyton (T.) mentagrophytes Type VIII are on the rise in India and noteworthy for their predominance. It would not be wrong assume that travel migration responsible spread of T. from India, with many strains resistant terbinafine, other parts world. From September 2016 until March 2020, a total 29 (India) were isolated. All patients residents Germany: 12 females, 15 males gender remaining two was assignable. Patients originated (11), Pakistan...
Rare variants in the genes IL36RN, CARD14 and AP1S3 have been identified to cause or contribute pustular skin diseases, primarily generalized psoriasis (GPP).To better understand disease relevance of these genes, we screened our cohorts patients with diseases [primarily GPP palmoplantar (PPP)] for coding changes three genes. Carriers single heterozygous IL36RN mutations were a second mutation IL36RN.Coding exons sequenced 67 - 61 GPP, two acute exanthematous pustulosis four acrodermatitis...
Abstract Numerous comorbidities and cofactors have been known to influence wound healing processes. In this multicentre study, clinical data of 1 000 patients with chronic leg ulcers from ten specialised dermatological care centers were analysed. The patient cohort comprised 567 females 433 males an average age 69·9 years. wounds persisted on for 40·8 months had a mean size 43·7 cm 2 . Venous represented the most common entity accounting 51·3% all wounds, followed by mixed‐type in 12·9%...
Abstract: Depression is a very common comorbidity in patients with chronic wounds. At least 30% of those suffer from depressive symptoms or anxiety. To measure impairment on daily life, different quality life (QoL) questionnaires can be used as well specialized to evaluate levels depression. In this review, we present some the current measurement tools and effects depression QoL. often associated wound duration, odor wounds, furthermore pain immobility. On other hand, might reduce healing...
Calciphylaxis (CP) is a serious, potentially life-threatening disease that presents with medial calcification of small-sized vessels and painful ischemic ulcerations. Although calciphylaxis frequently seen in patients end-stage kidney on dialysis (calcific uremic arteriolopathy, CUA), there are reported cases nonuremic (NUC), which often remain undiagnosed. We conducted retrospective chart review at our dermatological hospital evaluated data concerning the epidemiology, comorbidities,...
Necrobiosis lipoidica (NL) is a rare granulomatous disorder of unknown etiology which can manifest in ulcerative skin lesions and widely recognised association with diabetes mellitus. Our aim was to improve knowledge about the epidemiology clinical course NL evaluate treatment approaches. This multicentre retrospective study covered data from 52 patients lower leg, treated between 2006 2011. Data three German dermatological centres were analysed. Twelve men 40 women, aged 15 87 years,...
Summary Background In almost every chronic wound different bacteria species can be detected. Patients and methods Retrospective, multicenter evaluation of bacterial swab results from 2010 2011 in patients with leg ulcer treated 10 dermatologic care centers 5 regions Germany. Results Data 970 were analyzed. Staphylococcus aureus was detected 47.6 % the patients, 8.6% these methicillin‐resistant (MRSA). Pseudomonas aeruginosa found 31.1 %, enterobacteria 28.6 Proteus mirabilis 13.7 patients....
Necrobiosis lipoidica (NL) is a rare granulomatous disorder of unknown aetiology which can manifest in ulcerative skin lesions and widely recognised association with diabetes. We evaluated total 100 patients to improve knowledge about the epidemiology clinical course NL. Additionally we focused on treatment options according evidence level expert opinion. To examine features necrobiosis give recommendations for topical systemic treatment. This multicentre retrospective study covers data from...
Patients with chronic leg ulcers typically experience contact allergy to topical treatments. Although declared as hypoallergenic, modern wound dressings have caused several reported cases of allergy. The aim the study was evaluate any allergenic potential in patients ulcers. Seventy-one were included our prospective observation. Patch tests performed a selection 10 and selected allergens according series German Contact Dermatitis Research Group (DKG). Of 70 eligible for evaluation, 12 (17%)...
Pain is a ubiquitous problem in patients with chronic leg wounds. The pain may be caused by the underlying pathology of ulceration, wound, wound treatment, or complications such as skin irritation around ulcer. objectives this research were to evaluate level suffering endured because their ulcer-related pain, and whether how treated. In addition, determine influences quality life health status. 2010, data collected order characterize socio-demographic facts, age, gender, co-morbidity,...
<b><i>Background:</i></b> Necrobiosis lipoidica (NL) is a rare granulomatous disorder of unknown aetiology. Randomized controlled studies are not available due to it being an orphan disease. <b><i>Objectives:</i></b> We evaluated patients in 2 dermatological centres cluster data about epidemiology, the therapeutic approaches for NL, and their efficacy. <b><i>Materials Methods:</i></b> Comorbidity efficacy applied...
An increasing number of chronic wounds in our society require strategies to improve wound healing and closure. One several options is skin transplantation. In this article, we focus on the transplantation tissue engineered autologous epidermal sheets derived from outer root sheath (ORS) cells patients' hair.Out stem ORS anagen hair, keratinocytes are cultured ex vivo organotypic cultures form a multilayered equivalent (EpiDex, EuroDerm Biotech & Aesthetics, Stuttgart, Germany). These placed...
Up to one-third of patients with T cell large granular lymphocyte (T-LGL) leukemia display symptoms rheumatoid arthritis (RA). In Crohn's disease and psoriasis, treatment tumor necrosis factor (TNF) inhibitors is associated hepatosplenic γδ lymphoma clonal expansion cells, respectively. This study was undertaken determine the prevalence T-LGL cells in RA define risk factors for this rare hematologic malignancy.A total 529 were recruited between November 2013 August 2015. Eight-color flow...
The possible impact of nutritional status on healing and course disease in patients with chronic wounds is widely suggested, however, most data are based small groups no control group minor afflictions. Clear diagnostic strategies missing. To analyse detail the wound relative to healthy controls a large patient population. We screened 50 for their body mass index (BMI), Mini-Nutritional Assessment (MNA), Nutritional Risk Screening (NRS), as well additional laboratory investigations....
<b><i>Background:</i></b> Onychomycosis is one of the most prevalent nail disorders in adults, where conventional topical therapy often protracted and cases ineffective. On other hand, systemic/oral not suitable for all patients might be associated with relevant side effects. Therefore, laser can used as an alternative to or extension existing treatment protocols. <b><i>Objectives:</i></b> We diode onychomycosis evaluate efficacy this single...
Over 30% of women in Canada undergo an abortion. Despite the prevalence procedure, stigma surrounding abortion leads to barriers for access this service. The vast majority care is concentrated urban settings. There evidence support utilization innovative mobile and other technology solutions empower safely effectively self-manage aspects process. This study part 1 a 3-phase that utilizes user-centered design methodology develop digital health solution specifically follow-up after induced...