- Microbial Metabolic Engineering and Bioproduction
- Biofuel production and bioconversion
- Fungal and yeast genetics research
- Microbial Natural Products and Biosynthesis
- Genomics and Phylogenetic Studies
- Algal biology and biofuel production
- Fermentation and Sensory Analysis
- Enzyme Production and Characterization
- Microbial Fuel Cells and Bioremediation
- CRISPR and Genetic Engineering
- RNA and protein synthesis mechanisms
- Enzyme Catalysis and Immobilization
- Polyamine Metabolism and Applications
- Anaerobic Digestion and Biogas Production
- Plant-Microbe Interactions and Immunity
- Plant Gene Expression Analysis
- Plant biochemistry and biosynthesis
- Biochemical and Structural Characterization
- Biochemical and biochemical processes
- Microbial Metabolites in Food Biotechnology
- Carbohydrate Chemistry and Synthesis
- Microbial Metabolism and Applications
- Chemical Synthesis and Analysis
- Microbial Community Ecology and Physiology
- Catalysis for Biomass Conversion
Shanghai Jiao Tong University
2016-2025
Cell Biotech (South Korea)
2023
Biocat
2023
State Key Laboratory of Microbial Metabolism
2016-2021
Kasetsart University
2020
Synthetic Biologics (United States)
2020
Dalian University of Technology
2008-2018
Dalian University
2009-2018
Bioscience (China)
2009
Myongji University
2004
Yeast strains that are tolerant to multiple environmental stresses highly desired for various industrial applications. Despite great efforts in identifying key genes involved stress tolerance of budding yeast Saccharomyces cerevisiae, the effects de novo purine biosynthesis on still not well explored. Our previous studies showed zinc sulfate addition improved acetic acid tolerance, and were further investigated this study. Three biosynthesis, namely, ADE1, ADE13, ADE17, significantly...
Enhanced environmental stress tolerance is important for microbial production of biofuels and biobased chemicals. However, the roles chromatin regulation in bioproduction remain unclear. Here, we explore effects Ino80, core subunit INO80 remodeling complex, on yeast adaptation. We found that deletion led to increased sensitivity budding Saccharomyces cerevisiae acetic acid, which a common inhibitor lignocellulosic biomass also serves as food preservative. Integrated ATAC-seq RNA-seq analyses...
Microalgal strains of Scenedesmus obliquus have the great potential for production biofuels, CO2 fixation, and bioremediation. However, metabolic engineering S. to improve their useful phenotypes are still not fully developed. In this study, strain CPC2 was genetically engineered promote autotrophic growth lipid productivity. The overexpression plasmid containing type 2 diacylglycerol acyltransferse (DGAT) gene DGTT1 from Chlamydomonas reinhardtii constructed transformed into CPC2, positive...
Gram-negative bacteria of the genus Serratia are potential producers many useful secondary metabolites, such as prodigiosin and serrawettins, which have applications in environmental bioremediation or pharmaceutical industry. Several strains produce serrawettin W1 main bioactive compounds, biosynthetic pathways co-regulated by quorum sensing (QS). In contrast, strain, can simultaneously W2, has not been reported. This study focused on analyzing genomic sequence sp. strain YD25T isolated from...
Saccharomyces cerevisiae is widely studied for production of biofuels and biochemicals. To improve efficiency under industrially relevant conditions, coordinated expression multiple genes by manipulating promoter strengths an efficient approach. It known that gene highly dependent on the practically used environmental conditions subject to dynamic changes. Therefore, investigating activities S. different culture in time points, especially stressful great importance. In this study, various...
The purpose of this study was to valorize oil palm empty fruit bunch (EFB) and fiber (PF) from mills produce fuel ethanol. Chemical-free fractionation EFB PF using hot-compressed water (HCW) pretreatment at temperatures ranging 150 200ºC 30 bars reaction times for 5, 15, 25 min applied remove most hemicellulose partial lignin fractions into liquid phase. Comparison the effects different commercial cellulase enzyme complexes (Accellerase 1500, Cellic® Ctec2, Htec2 Ctec2+Htec2) on HCW...
In this study, Scenedesmus sp. FSP3 was cultured using a two-stage culture strategy for CO2 fixation and lutein production. During the first stage, propylene carbonate added to medium, with 5% introduced promote rapid growth of microalgae. second stage cultivation, NaCl concentration 156 mmol L-1 light intensity 160 μmol m-2 s-1 were used stimulate accumulation in microalgal cells. By method, high production simultaneously achieved. The biomass productivity carbon rate reached 0.58 g d-1...