A5090211244- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Helicobacter pylori-related gastroenterology studies
- Metastasis and carcinoma case studies
- Gastrointestinal Tumor Research and Treatment
- Genetic factors in colorectal cancer
- Gastroesophageal reflux and treatments
- Gastrointestinal disorders and treatments
- Eosinophilic Esophagitis
- Gut microbiota and health
- Diverticular Disease and Complications
- Radiomics and Machine Learning in Medical Imaging
- AI in cancer detection
- Esophageal Cancer Research and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastrointestinal Bleeding Diagnosis and Treatment
- Global Cancer Incidence and Screening
- Colorectal Cancer Surgical Treatments
- Esophageal and GI Pathology
- Cancer-related molecular mechanisms research
- Lymphoma Diagnosis and Treatment
- Microscopic Colitis
- Pancreatic and Hepatic Oncology Research
- Radiopharmaceutical Chemistry and Applications
- Antiplatelet Therapy and Cardiovascular Diseases
Kangbuk Samsung Hospital
2016-2025
Sungkyunkwan University
2016-2025
Ewha Womans University
2021
Seoul National University Hospital
2020-2021
Korea University
2020
Incheon St. Mary's Hospital
2020
Hanyang University Guri Hospital
2020
Yonsei University
2020
Severance Hospital
2020
Seoul National University
2012-2015
Background/Aims Colonoscopic polypectomy is the best diagnostic and therapeutic tool to detect prevent colorectal neoplasms. However, previous studies have reported that 17% 28% of polyps are missed during colonoscopy. We investigated miss rate neoplastic factors associated with from quality-adjusted consecutive colonoscopies. Methods reviewed medical records patients who were found at a examination center Kangbuk Samsung Hospital between March 2012 February 2013. Patients referred single...
Purpose To compare the effectiveness of transarterial chemoembolization (TACE), radiofrequency ablation (RFA), and hepatic resection (HR) in patients with small single-nodule hepatocellular carcinoma by using inverse probability weighting to control selection bias. Materials Methods This retrospective cohort study was approved institutional review board, requirement obtain informed consent waived. The included 197 consecutive (146 men 51 women; mean age ± standard deviation, 57.4 years 9.7)...
Studies on the gastric microbiota associated with precancerous lesions remain limited. This study aimed to profile mucosal in patients Helicobacter pylori-negative lesions. Gastric samples were obtained from 67 H. patients, including those chronic gastritis (CG), intestinal metaplasia (IM), and dysplasia. The V3–V4 region of 16S rRNA gene was sequenced analyzed. No significant difference observed alpha or beta diversity among groups. However, a taxonomic analysis revealed enrichment...
Helicobacter pylori infection is one of the most common infectious diseases worldwide. H. responsible for substantial gastrointestinal morbidity with a high disease burden. Since revision Clinical Practice Guidelines in 2013 Korea, eradication rate has gradually decreased use clarithromycin based triple therapy. According to nationwide randomized controlled study by Korean College and Upper Gastrointestinal Research released 2018, intention-to-treat was only 63.9%, which mostly due increased...
While DNA methylation and gastric microbiome are each associated with cancer (GC), their combined role in predicting GC remains unclear. This study investigated the potential of a signature to predict
Abstract Background and Aim The present study aimed to evaluate the non‐inferiority of low‐volume oral sulfate solution (OSS) 4‐L polyethylene glycol (PEG) solutions administered in a split‐dose regimen as bowel preparation for colonoscopy. safety tolerability were also compared between two regimens. Methods In this prospective, randomized, single‐blind, active‐control, parallel group, trial, consecutive outpatients health checkup recipients aged 19–65 years undergoing elective colonoscopy...
The original eCura system was designed to stratify the risk of lymph node metastasis (LNM) after endoscopic resection (ER) in patients with early gastric cancer (EGC). We assessed effectiveness a modified for reflecting characteristics undifferentiated-type (UD)-EGC. Six hundred thirty-four who underwent non-curative ER UD-EGC and received either additional surgery (radical group; n=270) or no further treatment (no n=364) from 18 institutions between 2005 2015 were retrospectively included...
Min Seob Kwak, Jae Myung Cha, Hyo-Joon Yang, Dong Il Park, Kyeong Ok Kim, Jun Lee, Jeong Eun Shin, Young-Eun Joo, Jongha Jeong-Sik Byeon, Hyun Gun Kim,. Gut and Liver 2019;13:176-82. https://doi.org/10.5009/gnl18214
Abstract Background and Aims Little is known about how to include adults < 50 years in colonoscopy screening. This study aimed derive a risk‐scoring model incorporating laboratory indicators for metabolic risks predict advanced colorectal neoplasia (ACN) asymptomatic Korean both younger older than years. Methods In this cross‐sectional study, 70 812 consecutive adult recipients of screening single health check‐up center Korea between 2003 2012 were enrolled. A risk score was developed...
Aberrant DNA methylation has a specific role in field cancerization. Certain molecular markers, including secreted frizzled-related protein 2 (SFRP2), tissue factor pathway inhibitor (TFPI2 ), N-Myc downstream-regulated gene 4 (NDRG4) and bone morphogenic 3 (BMP3), have previously been shown to be hypermethylated colorectal cancer (CRC). We aim examine cancerization CRC based on the presence of aberrant normal-appearing from patients.We investigated promoter 34 patients five individuals with...
The role of the gastric mucosal microbiome in Helicobacter pylori-negative cancer (GC) remains unclear. Therefore, we aimed to characterize microbial alterations and host inflammatory cytokine responses H. GC. Gastric samples were obtained from 137 patients with GC (n = 45) controls (chronic gastritis or intestinal metaplasia, n 92). We performed 16S rRNA gene sequencing 67), a quantitative reverse transcription-polymerase chain reaction determine relative mRNA expression levels TNF (tumor...
The eCura system, a scoring model for stratifying the lymph node metastasis risk after noncurative endoscopic resection early gastric cancer (EGC), has been internally validated, primarily differentiated-type EGC. We aimed to externally validate this undifferentiated-type
The novel curability criteria for elderly (EL) patients have been proposed to stratify their risk of lymph node metastasis (LNM), following non-curative endoscopic submucosal dissection (ESD) early gastric cancer (EGC). Hence, this study aimed evaluate the effectiveness EL and compare them with those well-known eCura system. A retrospective analysis was performed on 143 who did not meet curative ESD at a tertiary hospital in Korea between 2011 2022. Of these, 102 underwent additional...
The Korean guidelines for Helicobacter pylori treatment were revised in 2020, however, the extent of adherence to these clinical practice remains unclear. Herein, we initiated a prospective, nationwide, multicenter registry study 2021 evaluate current management H. infection Korea. This interim report describes and their impact on first-line eradication rates. Data patient demographics, diagnoses, treatments, outcomes collected using web-based electronic case form. A total 7,261 patients...
Non-operative management (NOM) has emerged as a promising organ-preserving strategy for patients with rectal cancer who achieve clinical complete response (cCR) after neoadjuvant chemoradiotherapy (CRT). However, no standardized treatment protocol been established watch-and-wait strategies. This prospective study evaluated oncological outcomes of NOM combined four months adjuvant capecitabine. Patients resectable (≤8 cm from the anal verge, cT2-4 or N+) underwent CRT (50-54 Gy in 25-27...