A5002520132- Airway Management and Intubation Techniques
- Respiratory Support and Mechanisms
- Statistical Methods and Bayesian Inference
- Obesity, Physical Activity, Diet
- Statistical Methods and Inference
- Cardiac Arrest and Resuscitation
- Renal Transplantation Outcomes and Treatments
- Tracheal and airway disorders
- Vitamin D Research Studies
- Bone health and osteoporosis research
- Neonatal Respiratory Health Research
- Obstructive Sleep Apnea Research
- interferon and immune responses
- Emergency and Acute Care Studies
- Treatment of Major Depression
- Bipolar Disorder and Treatment
- Attention Deficit Hyperactivity Disorder
- Infant Development and Preterm Care
- Parathyroid Disorders and Treatments
- Dialysis and Renal Disease Management
- Neuroscience of respiration and sleep
- Electroconvulsive Therapy Studies
- Nutrition and Health in Aging
- Organ Donation and Transplantation
- Advanced Statistical Methods and Models
University of Pennsylvania
2016-2025
Children's Hospital of Philadelphia
2016-2025
Philadelphia University
2007-2024
ME Association
2022
Acuitas Therapeutics (Canada)
2022
Cancer Research And Biostatistics
2007-2021
DaVita Clinical Research (United States)
2019
Translational Research Informatics Center (Japan)
2017
Loyola University Chicago
2017
Temple University
2013-2015
<h3>Importance</h3> The Press Ganey Outpatient Medical Practice Survey is used to measure the patient experience. An understanding of patient- and physician-related determinants experience may help identify opportunities improve health care delivery physician ratings. <h3>Objective</h3> To evaluate associations between as measured by scores on survey patient-physician racial/ethnic gender concordance. <h3>Design, Setting, Participants</h3> A cross-sectional analysis surveys returned for...
BACKGROUND. The prevalence and seriousness of childhood obesity has prompted calls for broad public health solutions that reach beyond clinic settings. Schools are ideal settings population-based interventions to address obesity. OBJECTIVE. purpose this work was examine the effects a multicomponent, School Nutrition Policy Initiative on prevention overweight (85.0th 94.9th percentile) (&gt;95.0th among children in grades 4 through 6 over 2-year period. METHODS. Participants were 1349...
Although extracorporeal cardiopulmonary resuscitation (E-CPR) can result in survival after failed conventional CPR (C-CPR), no large, systematic comparison of pediatric E-CPR and continued C-CPR has been reported.Consecutive patients <18 years old with events ≥10 minutes duration reported to the Get With Guidelines-Resuscitation registry between January 2000 December 2011 were identified. Hospitals grouped by teaching status location. Primary outcome was discharge. Regression modeling...
The GEEQBOX toolbox analyzes correlated data via the method of generalized estimating equations (GEE) and quasi-least squares (QLS), an approach based on GEE that overcomes some limitations have been noted in literature. is currently able to handle follows a normal, Bernoulli or Poisson distribution, assumed AR(1), Markov, tri-diagonal, equicorrelated, unstructured working independence correlation structure. This for use with MATLAB.
Objectives. To evaluate health care and financial outcomes in a population of Medicaid-insured asthmatic children after comprehensive asthma intervention program. Design. Controlled clinical trial. Setting. Pediatric allergy clinic an urban, tertiary children's hospital. Subjects. Eighty children, 2 to 16 years old, with history frequent use emergent services for asthma. Intervention. Children the group received education medical treatment setting pediatric clinic. An outreach nurse...
To determine whether naturally acquired serum IgA and IgG antibodies were associated with protection against rotavirus infection illness, a cohort of 200 Mexican infants was monitored weekly for excretion diarrhea from birth to age 2 years. Serum samples collected during the first week after every 4 months tested anti—rotavirus IgG. Children an titer >1:800 had lower risk (adjusted relative [aRR], 0.21; P < .001) (aRR, 0.16; = .01) protected completely moderate-to-severe diarrhea. However,...
We conducted a randomized, double-blind, placebo-controlled efficacy and tolerability trial of Matricaria recutita (chamomile) extract therapy in patients with mild to moderate generalized anxiety disorder (GAD). hypothesized that chamomile would be superior placebo reducing GAD symptoms comparable profile.Sixty-one outpatients were enrolled, 57 randomized either double-blind (n = 28) or 29) for 8 weeks. The study was powered detect statistically significant clinically meaningful group...
Glucocorticoids suppress bone formation, impair growth, and induce obesity. We determined the effects of long-term treatment with glucocorticoids on mineral content in children glucocorticoid-sensitive nephrotic syndrome, a disorder minimal known independent bone.We performed dual-energy x-ray absorptiometry whole body spine 60 adolescents syndrome 195 control subjects. used linear regression analysis log-transformed values to compare patients that controls.Patients had received an average...
Silent infarcts have been reported most commonly in school-aged children with homozygous sickle cell disease (SCD-SS) and are associated neurocognitive deficits. However, the prevalence of silent younger SCD-SS is not well defined. In this retrospective study, brain magnetic resonance imaging angiography (MRI/A) studies performed before 6 years age a cohort were analysed abnormalities was calculated. Clinical laboratory parameters compared between groups without infarcts. Sixty-eight 96 had...
Objective Retrospective studies have limitations in predicting perioperative risk following adenotonsillectomy children with obstructive sleep apnea syndrome (OSAS). Few prospective exist. We hypothesized that demographic and polysomnographic (PSG) variables would predict respiratory general complications. Study Design Prospective, observational cohort study. Setting Pediatric tertiary center. Subjects Methods Consecutive undergoing for OSAS within 12 months of PSG were evaluated...
We aimed to determine the incidence of electrographic seizures in children pediatric intensive care unit who underwent EEG monitoring, risk factors for seizures, and whether were associated with increased odds mortality.Eleven sites North America retrospectively reviewed a total 550 consecutive units monitoring. collected data on demographics, diagnoses, clinical mental status at onset, background, interictal epileptiform discharges, length stay, in-hospital mortality.Electrographic occurred...
<b><i>Background:</i></b> Poor physical performance and frailty are associated with elevated risks of death disability. Chronic kidney disease (CKD) is also strongly these outcomes. The poor among CKD patients, however, not well established. <b><i>Methods:</i></b> We measured the Short Physical Performance Battery (SPPB; a summary test gait speed, chair raises balance; range 0-12) five elements 1,111 Renal Insufficiency Cohort participants....
Abstract Objective: To determine the relationship between relative weight and school attendance among elementary schoolchildren. Research Methods Procedures: A total of 1069 fourth to sixth graders from nine schools in inner city Philadelphia, PA, were part an ongoing randomized control trial assess prevention strategies for obesity. The mean rate students eligible free/reduced meals was 82.9 ± 11.5%. Weight measured second semester academic year. Absentee data entire year recorded by...
Sex and race differences in bone development are associated with growth, maturation, body composition.The aim of the study was to determine independent effects sex, race, puberty on cortical muscle-bone relations children young adults.We conducted a cross-sectional 665 healthy participants (310 male, 306 black) ages 5-35 yr.Tibia peripheral quantitative computed tomography measures were made mineral content (BMC) density (BMD), periosteal (Peri) endosteal circumferences, section modulus...
Objective The authors examined the safety and efficacy of long-term fluoxetine monotherapy, lithium placebo therapy in preventing relapse recurrence bipolar type II major depressive episode. hypothesized that monotherapy would be superior to with a similar hypomanic mood conversion rate. Method Patients at least 18 years old who recovered from their episode during initial open-label were randomly assigned receive 50 weeks double-blind 10–40 mg/day, 300–1200 or placebo. primary outcome...
The impact of multiple tracheal intubation (TI) attempts on outcomes in critically ill children with acute respiratory failure is not known. objective our study to determine the association between number TI and severe desaturation (SpO2 < 70 %) adverse associated events (TIAEs). We performed an analysis a prospective multicenter database (National Emergency Airway Registry for Children: NEAR4KIDS). Primary exposure variable was trichotomized as one, two, or ≥3 attempts. Estimates were...