A5068753497- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Surgical Treatments
- Pancreatitis Pathology and Treatment
- Inflammatory Biomarkers in Disease Prognosis
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Cancer, Lipids, and Metabolism
- Pediatric Hepatobiliary Diseases and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Frailty in Older Adults
- Nutrition and Health in Aging
- Child Nutrition and Feeding Issues
- Colorectal and Anal Carcinomas
- Biliary and Gastrointestinal Fistulas
- Gastrointestinal Tumor Research and Treatment
- Neuroendocrine Tumor Research Advances
- IgG4-Related and Inflammatory Diseases
- Colorectal Cancer Screening and Detection
- Dysphagia Assessment and Management
- Gastrointestinal disorders and treatments
- MRI in cancer diagnosis
- Ureteral procedures and complications
- Cancer-related molecular mechanisms research
- Pulmonary Hypertension Research and Treatments
Sendai Medical Center
2019-2025
Nagoya City University
2024
Minoh City Hospital
2004
Mie University
2004
Abstract Aim Endoscopic decompression using the self‐expandable metallic colonic stent ( SEMS ) or transanal tube TDT can convert emergency surgery into elective one‐stage for obstructive colorectal cancer OCRC ). The aim of present study was to clarify effect and on long‐term oncological outcomes. Methods We retrospectively analyzed 76 consecutive pathological stage II III patients who were inserted with as a bridge curative between 2009 2018. Results There 53 cases 23 cases. tumor located...
A 56-year-old woman with high-grade or invasive intraductal papillary mucinous neoplasm (IPMN) underwent 3 pancreatic surgeries for initial and recurrent IPMN lesions. Immunostaining genetic analyses of all lesions revealed a consistent mutation in KRAS loss STK11, indicating the same origin these possibility dissemination. Other immunostaining findings, such as MUC expression high Ki-67 labeling index, were among supported their malignant potential. IPMNs STK11 may benefit from tailored...
Background Pulmonary arterial hypertension (PAH) is a severe and rare disease in the cardiopulmonary system. Its pathogenesis involves vascular remodeling of pulmonary artery, which results progressive increases pressure. Chronically increased pressure causes right ventricular hypertrophy subsequent heart failure. attributed to excessive proliferation migration smooth muscle cells (PASMCs), are induced by enhanced Ca 2+ signaling following up-/down-regulation ion channel expression....
Background/Aims: Endoscopic biliary drainage using self-expandable metallic stents (SEMSs) for malignant strictures occasionally induces acute cholecystitis (AC). This study evaluated the efficacy of prophylactic gallbladder (GBS) during SEMS placement.Methods: Among 158 patients who underwent placement between January 2018 and March 2023, 30 attempted to undergo GBS before were included.Results: Technical success was achieved in 21 cases (70.0%). The mean diameter cystic duct more...
The factors affecting the detection rate of lymphoplasmacytic sclerosing pancreatitis (LPSP) using endoscopic ultrasound-guided tissue acquisition (EUS-TA) in patients with type 1 autoimmune (AIP) have not been thoroughly studied. Therefore, we conducted a retrospective study to identify predictive for histologically detecting level or 2 LPSP EUS-TA. Fifty AIP were included this study, and primary outcome measures Multivariate analysis identified use fine needle biopsy (FNB) needles as...
A 75-year-old woman who previously underwent distal gastrectomy with Roux-en-Y reconstruction had acute calculous cholangitis continuous abdominal pain, jaundice, and signs indicating sepsis. Enhanced CT revealed a stricture at the bile duct multiple stones both upstream downstream (Fig. 1). Acute improved after percutaneous transhepatic gallbladder drainage (PTGBD) as temporizing intervention (endoscopic was avoided because of patient's unstable condition). Using single-balloon enteroscope,...
Background/Aims: For early gastric cancer (EGC) treated using endoscopic submucosal dissection (ESD) with poor curability defined by the Japanese Guidelines (non-curative EGC, N-EGC), additional gastrectomy has been recommended. However, N-EGC patients without often die of other diseases within a relatively short interval after ESD. It unclear whether is beneficial or not for such patients. The aim this study was to clarify predictors short-term survival Methods: One hundred six were...
Understanding the relationship between sarcopenia and malignancy is increasingly important since they inevitably affect aging population. We investigated clinical significance of in nonmetastatic obstructive colorectal cancer (OCRC) patients who were inserted self-expandable metallic stent underwent curative surgery.Plain cross-sectional CT images obtained before stenting retrospectively analyzed 92 patients. Muscle volume loss (myopenia) decreased muscle quality (myosteatosis) evaluated as...
Abstract Objectives A difficult step in endoscopic ultrasound (EUS)‐guided drainage procedures is dilation of the puncture tract before stent deployment. The efficacy and safety a novel spiral dilator, Tornus ES, for EUS‐guided were investigated this study. Methods This study was conducted as prospective, single‐arm, observational at Sendai City Medical center. Dilation using dilator attempted all cases. primary outcome technical success rate which defined successful placement tract....
We present the case of a 54-year-old woman who was diagnosed with intraductal papillary neoplasm bile duct (IPNB) in remnant intrapancreatic duct, 37 years after surgery for congenital biliary dilatation. Endoscopic ultrasonography revealed papillary, low-echoic mass and peroral cholangioscopy mucosa. A pancreaticoduodenectomy performed, patient pathologically type 1 pancreatobiliary-type IPNB associated invasive carcinoma. As similar atypical epithelium identified pancreatic it suggested...
Objectives: The geriatric nutritional risk index (GNRI) is a nutrition-related calculated easily from serum albumin and the ratio of body weight to ideal weight. We investigated prognostic values GNRI in elderly patients with obstructive colorectal cancer (OCRC) who had self-expandable metallic stent inserted as bridge curative surgery.
Background/Aims The aim of this study was to evaluate the safety sedation with propofol as an alternative benzodiazepine drugs in outpatient endoscopy. Methods In prospective study, examinees who underwent endoscopy under and submitted a nextday questionnaire providing informed consent were evaluated. Periprocedural acute responses, late adverse events within 24 hours, examinee satisfaction Results Among 4,122 patients received 17,978 outpatient-based endoscopic examinations performed...
In patients with Roux-en-Y (RY) reconstruction for gastric resection, the newly defined "fold disruption" (FD) sign can be useful to distinguish afferent limb from efferent at Y anastomosis when balloon endoscopy-assisted endoscopic retrograde cholangiopancreatography (BE-ERCP) is performed. The FD was as findings of internal folds disrupted toward and continued anastomosis. this prospective observational study, accuracy evaluated those who underwent BE-ERCP after resection RY...
This study aimed to clarify the efficacy and safety of pancreatic duct lavage cytology combined with a cell-block method (PLC-CB) for possible ductal adenocarcinomas (PDACs).This included 41 patients suspected PDACs who underwent PLC-CB mainly because they were unfit undergoing endoscopic ultrasonography-guided fine needle aspiration. A 6-Fr double lumen catheter was used perform PLC-CB. Final diagnoses obtained from findings resected specimens or clinical outcomes during surveillance after...
A woman, aged 78, was admitted to hospital for endoscopic balloon dilatation of a tight esophageal stricture caused by reflux esophagitis. As the difficult dilate and she refused surgery, treated placement self-expanding metal stent. After procedure, dysphagia resolved patient returned normal diet. Although remained asymptomatic, upper gastrointestinal endoscopy repeated after 29 months. Within stent, had an elevated somewhat nodular lesion that extended from proximal distal end stent (Fig....
Background/Aims: We aimed to investigate (1) promising clinical findings for the recognition of focal type autoimmune pancreatitis (FAIP) and (2) impact endoscopic ultrasound (EUS)-guided tissue acquisition (EUS-TA) on diagnosis FAIP.Methods: Twenty-three patients with FAIP were involved in this study, 44 resected pancreatic ductal adenocarcinoma (PDAC) included control group.Results: Multivariate analysis revealed that homogeneous delayed enhancement contrast-enhanced computed tomography...