A5100612389- Reconstructive Surgery and Microvascular Techniques
- Foot and Ankle Surgery
- Atrial Fibrillation Management and Outcomes
- Diabetic Foot Ulcer Assessment and Management
- Circular RNAs in diseases
- Cardiac Arrhythmias and Treatments
- Tendon Structure and Treatment
- Cardiac electrophysiology and arrhythmias
- Circadian rhythm and melatonin
- Venomous Animal Envenomation and Studies
- Rabies epidemiology and control
- MicroRNA in disease regulation
- Orthopedic Surgery and Rehabilitation
- Neuroinflammation and Neurodegeneration Mechanisms
- Cancer-related molecular mechanisms research
- Congenital limb and hand anomalies
- Endometrial and Cervical Cancer Treatments
- Endometriosis Research and Treatment
- Soft tissue tumor case studies
- Ga2O3 and related materials
- Genomics, phytochemicals, and oxidative stress
- Hippo pathway signaling and YAP/TAZ
- Burn Injury Management and Outcomes
- Covalent Organic Framework Applications
- Ferroptosis and cancer prognosis
Qilu Hospital of Shandong University
2012-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2025
Hainan Medical University
2024
Hubei University of Science and Technology
2024
Ministry of Education of the People's Republic of China
2023
Guiyang Medical University
2023
Affiliated Hospital of Guizhou Medical University
2023
Qingdao University
2023
Affiliated Hospital of Qingdao University
2023
Shandong University
2011-2022
Necroptosis is one of the common modes apoptosis, and it has an intrinsic association with cancer prognosis. However, role necroptosis-related long non-coding RNA LncRNA (NRLncRNAs) in uterine corpora endometrial (UCEC) not yet been fully elucidated at present. Therefore, present study designed to investigate potential prognostic value LncRNAs UCEC. In study, expression profiles clinical data UCEC patients were downloaded from TCGA database identify differentially expressed NRLncRNAs...
Abstract: Melatonin, an indolamine produced and secreted predominately by the pineal gland, exhibits a variety of physiological functions, possesses antioxidant antitumor properties. In this study, we have shown that pharmacologic concentration (1 m ) melatonin significantly reduced cell migration invasion T98G U251 glioma cells after 24‐hr treatment inhibited expression matrix metalloproteinase 2 (MMP 2) MMP 9. The inhibition was associated with its reduction intracellular basal free...
Sustaining proliferative signaling is one of the hallmarks cancer. Granulocyte-colony stimulating factor (G-CSF), a hematopoietic growth that controls proliferation and differentiation neural stem cells, may contribute to development glioma. In present study, we evaluated expression G-CSF its receptor (G-CSFR) in various grades glioma samples primary cell culture derived from glioblastoma patient as well different human lines. We showed G-CSFR were widely expressed by samples, The levels not...
Four tetraphenyl silsesquioxane based covalent-organic frameworks (sil-COFs) have been designed under a ctn or bor net topology as high-capacity hydrogen storage materials.
Melatonin, an endogenously produced neurohormone secreted mainly by the pineal gland, has a variety of physiological functions and neuroprotective effects. Saturated fatty acids (SFAs) have been known to induce neurotoxicity oxidative stress in central nervous system injuries neurodegenerative pathologies. However, effect melatonin on SFAs-induced cytotoxicity astroglial cells, if any, remained be explored. This study reports that primary cultured significantly attenuated palmitic acid...
miR-26a has been found to be downregulated in osteosarcoma (OS) when compared with normal control tissues and shown suppress the malignant behaviors of OS cells. The underlying mechanism, nevertheless, remains unknown. In our study, long noncoding RNA MALAT1, confirmed significantly upregulated OS, is first capable promoting proliferation migration by directly suppressing miR-26a-5p addition, we have identified forkhead box O1 (FOXO1) as a transcriptional factor MALAT1 that can negatively...
Abstract Background This study was to investigate the effects of recombinant human growth hormone (rhGh) on ischemia‐reperfusion (I/R) injury mouse flaps. Methods Healthy mice were randomly divided into four groups as follows: sham group, IR sham+rhGH group and IR+rhGH with 12 in each group. Skin pathology tested by hematoxylin eosin staining. The flap survival measured after 7 days. levels superoxide dismutase (SOD) malondialdehyde (MDA) determined using corresponding kit. interleukin...
Background The treatment of talus avascular necrosis (AVN) is challenging owing to its unique anatomical features. Despite decades studies, till date, there no appropriate for AVN. Therefore, surgeons need develop newer surgical methods. In the present study we introduce a new method, 3D printed partial replacement (PTR), treat and collapse (TNC).Methods A male patient with AVN underwent PTR in our hospital. morphology was quantified using computed tomography (CT) imaging. novel titanium...
Endometriosis is a common gynecological disease, and its underlying mechanisms remain elusive. Patients are at higher risk of recurrence after surgery or drug withdrawal. In this study, to identify potentially effective safe therapy for endometriosis, we screened potential target genes kaempferol on endometriosis using network pharmacology further validation. Network showed may suppress migratory invasive properties by modulating the phosphoinositide 3-kinase (PI3K) pathway downstream matrix...
Abstract Objective To analyze the vulnerability factors of snakebite patients in China. Methods Multi-stage random sampling was used as main method and snowball auxiliary method. The knowledge, attitude behavior among Chinese residents were investigated. Non-parametric test to compare percentage differences residents’ snakebite, generalized linear regression analysis influencing factors, comprehensively analyzed. Results A total 6338 subjects included this study, which 68.4% males, 58.6%...
Glioma is a common primary intracranial carcinoma with high incidence, recurrence, and motility. Single minded homolog 2-short form (SIM2-s), member of basic helix-loop-helix (bHLH) family, reported to be expressed in glioma might play role the invasion. In present study, we investigated importance SIM2-s invasion further explored potential mechanisms. We showed that targeting by interference technology could decrease cell adhesion fibronectin, induce aggregation cytoskeletal changes....
Screening of osteochondral lesions the talus (OLTs) from MR imags usually requires time and efforts, in most case with small size are often missed clinical practice. Thereore, it puts forward higher requirements for a more efficient OLTs screening method. To develop an automatic system (OLTs), we collected 92 MRI images patients ankle pain Qilu Hospital Shandong University proposed AI (artificial intelligence) aided lesion system, which is based on deep learning A two-stage detection method...
To observe and verify the key anatomies of DeLancey's three levels vaginal support theory through laparoscopic surgery by space dissection technique.The features stress performance related were observed analyzed in type C hysterectomy pelvic lymphadenectomy for cervical cancer natural exposures.The main ligament-like structure at level Ⅰ was uterosacral ligament, which acted as apical fixation sacral direction, while cardinal ligament mainly composed vascular system, lymph-vessels loose...
To introduce the application of Ilizarov techniques in treatment syndactyly. From January 2016 to 2019, 6 cases pediatric syndactyly were treated by simple external fixator device our hospital. The skin and soft tissue between involved fingers lengthened with slow traction. speed was controlled at 1–2 mm per day, six times a day. When length interphalangeal is up requirement, Z-plasty incision finger web flap performed separate fingers. Skin grafting generally not required. All had been...