- Orthopedic Surgery and Rehabilitation
- Bone fractures and treatments
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Elbow and Forearm Trauma Treatment
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Inflammasome and immune disorders
- Fermentation and Sensory Analysis
- Microbial Natural Products and Biosynthesis
- Tea Polyphenols and Effects
- Shoulder and Clavicle Injuries
- Fungal Biology and Applications
- Cancer-related molecular mechanisms research
- Phytochemistry and Biological Activities
- Nanomaterials for catalytic reactions
- Metal-Organic Frameworks: Synthesis and Applications
- Orthopaedic implants and arthroplasty
- Gout, Hyperuricemia, Uric Acid
- Phytochemicals and Antioxidant Activities
- Microbial Metabolism and Applications
- Covalent Organic Framework Applications
- Medical Imaging and Analysis
- TGF-β signaling in diseases
- Fibroblast Growth Factor Research
Shanghai University of Traditional Chinese Medicine
2025
Lanzhou University
2025
Henan University of Technology
2014-2024
Qilu Hospital of Shandong University
2012-2024
Southeast University
2024
Chemnitz University of Technology
2022-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Hebei GEO University
2024
First Affiliated Hospital of Kunming Medical University
2023
Kunming Medical University
2023
Abstract Laser‐induced graphene (LIG) is a promising technology enabling cost‐effective, scalable, and high surface area 3D‐porous electrodes for electrochemical applications. Nitrate in water bodies harmful contaminant to humans the ecosystems. Its detection by sensors challenging due interference from nitrite. Herein, first time, LIG‐based sensor modified with electrodeposited silver dendrites (EdAg/LIG) without using surfactants proposed of nitrate tunable selectivity sensitivity. The...
Abstract Background Pulsed electromagnetic field (PEMF) is reported to be an effective adjunct for the management of nonunion long-bone fractures. Most studies implement PEMF treatment after 6 months or longer delayed union following fracture treatment. Despite these variations in treatment, early application a diagnosis postoperative has not been specifically analyzed. In this study, outcomes fractures treated with were evaluated as compared sham-treated control group. Methods prospective,...
Asthma is a chronic disease related to airway hyperresponsiveness and remodeling. Airway remodeling the important reason of refractory asthma associated with differentiation epithelia into myofibroblasts via epithelial-mesenchymal transition (EMT) increase process subepithelial fibrosis. There growing evidence that autophagy modulates However, underlying molecular mechanisms these effects are still unclear. In this study, we hypothesized Follistatin-like 1 (FSTL1) promotes EMT by...
The optimal method for the reduction and fixation of posterior malleolar fracture (PMF) remains inconclusive. Currently, both indirect direct techniques are widely used. We aimed to compare quality clinical outcome managed with technique through posterolateral approach or using ligamentotaxis. Patients a PMF involving over 25% articular surface were recruited assigned (DR) group (IR) group. Following fracture, was evaluated in post-operative CT images. Clinical radiological follow-ups...
Airway epithelial cell (AEC) necroptosis contributes to airway allergic inflammation and asthma exacerbation. Targeting the tumor necrosis factor-like ligand 1 A (TL1A)/death receptor 3 (DR3) axis has a therapeutic effect on asthmatic inflammation. The role of TL1A in mediating AECs challenged with ovalbumin (OVA) its contribution remains unclear.
Four tetraphenyl silsesquioxane based covalent-organic frameworks (sil-COFs) have been designed under a ctn or bor net topology as high-capacity hydrogen storage materials.
Lung adenocarcinoma (LUAD) is a highly mortal cancer. Tertiary lymphoid structures (TLS) are ectopic organs with similar morphological and molecular characters to secondary organ. The aim of this study investigate the prognostic effect gene signature associated TLSs, including B-cell-specific genes.Clinical data 515 LUAD patients in TGCA cohort were used examine relationship TLS immune microenvironment, tumor mutational burden (TMB), driver mutations. Patients divided into high group low...
Abstract Emerging evidence demonstrates that pyroptosis has been implicated in the pathogenesis of asthma. Gasdermin D (GSDMD) is executioner. The mechanism GSDMD asthma remains unclear. aim this study was to elucidate potential role asthmatic airway inflammation and remodeling. Immunofluorescence staining conducted on epithelial tissues obtained from both patients healthy controls (HCs) evaluate expression level N-GSDMD. ELISA used measure concentrations cytokines (IL-1β, IL-18, IL-17A,...
This work demonstrates the potential of laser-induced fibers as functionalization material for electrochemical sensors and implements copper phthalocyanine modified graphene electrodes to detect nitrite.
Pyroptosis was implicated in acute lung injury (ALI). Disulfiram is reported as an effective pyroptosis inhibitor by inhibiting gasdermin D(GSDMD). However, the function of executor GSDMD and treatment disulfiramon on ALI, especially whether it involved ALI-associated intestinal mucosal barrier impairment remains unclear. This study aims to explore role disulfiram' ALI related impairment.
Wheat and daqu, as raw materials, play important roles in spontaneous solid-state fermentation of Chinese Baijiu. Functional microorganisms contribute to the flavour However, studies on relationship between wheat functional daqu are very limited. This study investigated components Nongxiangxing (NXDQ) from northern China. Staphylococcus, Thermoactinomyces, unclassified_o_Enterobacterales, Kosakonia, Thermoascus, Thermomyces, Saccharomycopsis Aspergillus were predominant biomarkers made...
Satellite synthetic aperture radar interferometry (InSAR) has become a recognized and reliable surface deformation monitoring technology in recent years. However, the complexity of deformation, driven by various physical mechanisms, presents itself different forms such as secular trend, cyclical fluctuations, irregular variations time series. Consequently, limitations conventional InSAR technology, which relies on linear assumptions, make it challenging to meet requirements complex nonlinear...
Nongxiangxing-daqu (NXDQ), as a saccharification and fermentation agent, directly affects the flavor yield of fresh Nongxiangxing Baijiu (NXBJ). The difference in temperature owing to artificial turning operation leads formation superior (S) normal (N) grades NXDQ. Here, aiming explore discriminant characteristics two NXDQ, we studied physicochemical properties, volatile compounds microbial communities using HS-SPME-GC/MS high-throughput sequencing technology. NXDQ presented different...
Abstract The interaction of CO 2 laser with polyimide results in the formation laser-induced graphene (LIG) and other morphological transitions based on parameters, such as Laser-induced fibers (LIF) surface. However, a fundamental investigation LIF, its properties potential have not been explored until now. We aim therefore to provide novel insights into LIF by characterization structural, electrical, electrochemical, mechanical properties. Four different morphologies were identified...
We present a concise asymmetric synthesis of (-)-Bao Gong Teng A, 2-hydroxylated tropane alkaloid with hypotensive and miotic activities isolated from the Chinese herb Erycibe obtusifolia Benth. Using an Evans chiral auxiliary, we achieve regio- stereoselective 1,3-dipolar cycloaddition between p-chlorobenzyl pyridinium salt (R)-3-acryloyl-4-phenyloxazolidin-2-one, efficiently generating skeleton on decagram scale. This methodology provides rapid practical optically active A for further...