Zhongke Sun

ORCID: 0000-0002-9784-9769
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About
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Research Areas
  • Probiotics and Fermented Foods
  • Legume Nitrogen Fixing Symbiosis
  • Plant-Microbe Interactions and Immunity
  • Plant Reproductive Biology
  • Wheat and Barley Genetics and Pathology
  • Soybean genetics and cultivation
  • Gut microbiota and health
  • Plant Micronutrient Interactions and Effects
  • Bacteriophages and microbial interactions
  • Genomics and Phylogenetic Studies
  • Cancer Research and Treatments
  • Microbial Community Ecology and Physiology
  • Phytase and its Applications
  • Plant Stress Responses and Tolerance
  • Nematode management and characterization studies
  • Bacterial Genetics and Biotechnology
  • Protein Hydrolysis and Bioactive Peptides
  • Microbial Metabolites in Food Biotechnology
  • Biosensors and Analytical Detection
  • Potato Plant Research
  • Plant tissue culture and regeneration
  • Fermentation and Sensory Analysis
  • Mycotoxins in Agriculture and Food
  • Digestive system and related health
  • Nanoparticles: synthesis and applications

Henan University of Technology
2021-2025

Zhoukou Normal University
2015-2023

Luohe Medical College
2023

Nanyang Institute of Technology
2023

Zhengzhou University
2019-2021

Universität Ulm
2011-2015

Academy of Military Medical Sciences
2007-2014

Institute of Microbiology and Biotechnology
2014

Northwest A&F University
2008

National Center of Biomedical Analysis
2007

Autoinducer-2 (AI-2) molecules are one class of signalling involved in gene regulation dependent on population density a mechanism commonly referred to as quorum sensing (QS). AI-2 is produced by the methylthioadenosine/S-adenosyl-homocysteine nucleosidase LuxS. In present study, we characterise function bifidobacterial LuxS proteins address question whether these economically important bacteria able perform QS communication. All publically available genome sequences bifidobacteria harbour...

10.1371/journal.pone.0088260 article EN cc-by PLoS ONE 2014-02-05

Mycotoxins are toxic secondary metabolites mainly produced by filamentous fungal species that commonly contaminate food and feed. Aflatoxin B1 (AFB1) is extremely seriously threatens the health of humans animals. In this work, Bacillus megaterium HNGD-A6 was obtained showed a 94.66% removal ability AFB1 employing extracellular enzymes as degrading active substance. The degradation products were P1 (AFD1, C16H14O5) P2 (C14H16N2O2), their toxicity greatly reduced compared to AFB1. AttM gene...

10.1021/acs.jafc.3c05725 article EN Journal of Agricultural and Food Chemistry 2023-12-16

To investigate the molecular mechanisms underlying adaptation of Bifidobacterium longum to intestinal tract, we utilized a new model for rabbit culture B. and reported changes in proteomic profiles after incubation vivo environment. By 2D-PAGE coupled with matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) and/or electrospray tandem (ESI-MS/MS) analyses, strain NCC2705 grown vitro environments were compared. Confirmed by semiquantitative RT-PCR, which...

10.1021/pr0704940 article EN Journal of Proteome Research 2007-11-21

Microbial-assisted biofortification attracted much attention recently due to its sustainable and eco-friendly nature for improving nutrient content in wheat. An endophytic strain Bacillus altitudinis WR10, which showed sophistical regulation of iron (Fe) homeostasis wheat seedlings, inspired us test potential enhancing Fe grain. In this study, assays vitro indicated that WR10 has versatile plant growth-promoting (PGP) traits bioinformatic analysis predicted non-pathogenicity. Two inoculation...

10.3389/fnut.2021.704030 article EN cc-by Frontiers in Nutrition 2021-08-03

An indole–3–acetic acid producing Bacillus altitudinis WR10 was previously isolated from the root of wheat (Triticum aestivum L.). In this study, strain used for relieving abiotic stresses in under low phosphorus and high saline hydroponic co-culture models. Significantly, improved seed relative germination rate salinity stress (200/400 mM NaCl) dry weight seedlings (10 μM KH2PO3) when insoluble phosphates are available. To provide insights into its stress-alleviating properties,...

10.3390/microorganisms7110508 article EN cc-by Microorganisms 2019-10-29

Soil salinity is an important abiotic stress factor that seriously affects the crop growth and yield. Use of plant-derived microorganisms a promising strategy to alleviate salt stress. In previous study, endophytic strain Bacillus altitudinis WR10 isolated from wheat roots showed high resistance. this we investigated efficacy in improving tolerance its potential mechanisms using hydroponic test. Under stress, inoculation significantly increased lengths dry weights shoots, indicating improves...

10.3389/fpls.2022.941388 article EN cc-by Frontiers in Plant Science 2022-07-14

Bacteria utilize a quorum sensing (QS) system to coordinate gene expression by monitoring the concentration of molecules known as autoinducers (AI). In present study, we confirmed presence LuxS/AI-2 dependent QS in vancomycin-resistant Enterococcus faecalis V583. Then, cellular targets controlled AI-2 were identified comparative proteomics analysis order elucidate possible role E. faecalis. Results demonstrated 15 proteins that are differentially expressed upon addition AI-2, including...

10.1021/pr3002244 article EN Journal of Proteome Research 2012-08-03

Abstract To investigate the molecular mechanisms underlying carbohydrate uptake and connected metabolic pathways of Bifidobacterium longum NCC2705, proteomic profiles bacteria grown on different carbon sources including glucose, fructose, mannose, xylose, ribose, galactose were analyzed. Our results show that all sugars tested catabolized via bifid shunt. Sixty‐eight proteins exhibited changes in abundance threefold or greater identified by MS. A striking observation was differential...

10.1002/pmic.201100035 article EN PROTEOMICS 2011-04-15

Xylooligosaccharide (XOS) is an attractive prebiotic mainly due to its bifidogenic effect. However, commercial XOS with different compositions often applied in the food industry at doses without specifications. In this study, we evaluated activity of either mixtures or pure fractions degrees polymerization (DP), using three strains Bifidobacterium spp., including B. breve ATCC 15700, bifidum 29521, and animalis subsp. lactis HN019. Three growth indicators showed strain-specific XOS, was both...

10.3389/fnut.2022.858949 article EN cc-by Frontiers in Nutrition 2022-08-25

Wheat and daqu, as raw materials, play important roles in spontaneous solid-state fermentation of Chinese Baijiu. Functional microorganisms contribute to the flavour However, studies on relationship between wheat functional daqu are very limited. This study investigated components Nongxiangxing (NXDQ) from northern China. Staphylococcus, Thermoactinomyces, unclassified_o_Enterobacterales, Kosakonia, Thermoascus, Thermomyces, Saccharomycopsis Aspergillus were predominant biomarkers made...

10.1016/j.lwt.2023.115119 article EN cc-by-nc-nd LWT 2023-07-28

Among the fungal diseases, Fusarium head blight (FHB), caused by graminearum, is one of most destructive disease affecting wheat. This pathogen poses significant threats to global wheat production, leading substantial yield losses and contaminating grains with harmful mycotoxins. The chemical control FHB has become increasingly challenging due rise resistance, environmental concerns, effects climate change. review introduces a novel approach management through spray-induced gene silencing...

10.1186/s40538-025-00738-6 article EN cc-by-nc-nd Chemical and Biological Technologies in Agriculture 2025-03-04

Soybean is an important legume crop and has significant agricultural economic value. P4-ATPases (aminophospholipid ATPases, ALAs), one of the classes P-type can transport or flip phospholipids across membranes, creating maintaining lipid asymmetry playing crucial roles in plant growth development. To date, however, ALA gene family its expression patterns under abiotic biotic stresses have not been studied soybean genome. A total 27 GmALA genes were identified genome these unevenly...

10.1186/s12864-025-11468-2 article EN cc-by-nc-nd BMC Genomics 2025-03-20

The Candida tropicalis (C. tropicalis) named YB-3 was isolated by the Atmospheric and room temperature plasma mutagenesis from 6.5 g/L furfural tolerance. comprehensive transcriptomic analysis of performed. During stress treatment, C. protected cells oxidative damage increasing accumulation glutathione reductase gene expression antioxidant enzymes, with enhancement inositol phosphate synthase to maintain structural integrity transport function inner membrane system, thereby affecting cells'...

10.3390/ijms26072999 article EN International Journal of Molecular Sciences 2025-03-25
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