A5010550783- Hemodynamic Monitoring and Therapy
- Sepsis Diagnosis and Treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Diabetes Management and Research
- Heart Failure Treatment and Management
- Vitamin D Research Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Liver Disease and Transplantation
- Respiratory Support and Mechanisms
- Ultrasound in Clinical Applications
- Cardiovascular Syncope and Autonomic Disorders
- Electrolyte and hormonal disorders
- Cardiovascular Function and Risk Factors
- Occupational exposure and asthma
- Transplantation: Methods and Outcomes
- Potassium and Related Disorders
- Heart Rate Variability and Autonomic Control
- Sarcoidosis and Beryllium Toxicity Research
- Polyomavirus and related diseases
- Hip and Femur Fractures
- Pericarditis and Cardiac Tamponade
- Nosocomial Infections in ICU
- Pancreatic function and diabetes
- Brain Metastases and Treatment
- Diabetes Treatment and Management
Cleveland Clinic
2022-2024
Queen Medical
2023
Queen's Medical Center
2023
King's College London
2023
Jacobi Medical Center
2018-2021
Albert Einstein College of Medicine
2017-2021
College of New Rochelle
2019
Montefiore Medical Center
2016
Background: Patients with sepsis are at risk for developing sepsis-induced cardiomyopathy (SIC). Previous studies offer inconsistent results regarding the association of SIC and mortality. This study sought to assess whether is linked mortality in patients evaluate predictors development SIC.Methods: In this retrospective study, admitted medical intensive care unit a diagnosis absence acute coronary syndrome were included. was identified using transthoracic echo defined by new onset decline...
Adipose tissue inflammation and fibrosis appear to contribute insulin resistance in obesity. Vitamin D receptor (Vdr) genes are expressed by adipocytes, macrophages, fibroblasts, all of which could potentially play a role adipose fibrosis. As vitamin has been shown have direct anti-inflammatory effects on we determined whether specific receptor-mediated adipocytes impact ultimately resistance. We examined the repleting 25(OH)D-deficient, resistant, overweight-to-obese human subjects (n =...
Abstract Background Recurrent hypoglycemia blunts counter-regulatory responses to subsequent hypoglycemic episodes, a syndrome known as hypoglycemia-associated autonomic failure (HAAF). Since adrenergic receptor blockade has been reported prevent HAAF, we investigated whether the rise in plasma epinephrine contributes pathophysiology and interindividual differences susceptibility HAAF. Methods To assess role of 24 adult nondiabetic subjects underwent two 2-hour hyperinsulinemic clamp studies...
Abstract Leptomeningeal disease (LMD) is a rare complication of Merkel cell carcinoma (MCC), which has been described in limited case reports, none describe outcomes with IPI-NIVO. Here we patient PD-1 refractory MCC LMD durable response to A 69-year-old male diagnosed stage IIIA underwent left groin dissection and radiation. He developed recurrence distant lymph nodes started pembrolizumab (PEMBRO). Seven months after starting PEMBRO, he lower extremity weakness. Spine MRI showed involving...
Background Hyponatremia is a well-established poor prognostic marker in patients with heart failure. Whether the mortality risk comparable among different races of failure and hyponatremia unknown. Materials methods Consecutive admitted acute decompensated an admission sodium level<135 mEq/L from 1/1/2001 through 12/31/10 were identified. Patients divided into four groups based on self-reported race: white, African American, Hispanic other. Americans used as reference group for statistical...
To describe a case of sequential bilateral adrenal infarction and hemorrhage resulting in an unusual pattern function over time.A 50-year-old male with autoimmune antiphospholipid syndrome (APS) presented to the emergency room severe abdominal pain. Diagnostic studies performed included contrast-enhanced computerized tomographic (IV-CT) imaging abdomen pelvis, laboratory assessment hypothalamic-pituitary-adrenal axis.IV-CT pelvis on day 1 showed acute left gland infarction; cortisol level...
Ehlers-Danlos syndrome (EDS) is a group of rare genetic disorders that occur because abnormalities in collagen and extracellular matrix. The vascular subtype EDS (vEDS) an autosomal dominant disorder characterized clinically by arterial dissections, spontaneous intestinal perforations, pneumothoraces.1 We present unique case postmortem identification vEDS 60-y-old female after bilateral sequential lung transplantation. CASE DESCRIPTION A woman with 35-pack-year smoking history underwent...
Diffuse alveolar haemorrhage (DAH) after a generalized tonic-clonic seizure is rarely described illness likely involving physical disruption of alveolar-capillary interface similar to the mechanism neurogenic pulmonary oedema. Based on our review English literature, only 11 cases have been reported date. Recognition this sparsely entity important for optimal management, including avoidance medications that implicated in causing DAH. Current experience with two additional patients post-ictal...
Introduction The spino-pelvic alignment is increasingly recognized as crucial in the assessment of patients with spinal deformities. Three pelvic parameters originally described include incidence (PI), tilt (PT) and sacral slope (SS). PT, a positional parameter, has been demonstrated to correlate quality life clinical outcomes. Although measuring PT on sagittal radiographs simple, underexposed films malposition X-rays often result poor visibility femoral heads. In 2012, novel measurement,...
Pneumoconioses are a group of non-neoplastic pulmonary disorders caused by inhaled inorganic particles. Well-described pneumoconioses include asbestosis, silicosis, coal worker's pneumoconiosis, chronic beryllium disease, and hard metal lung disease. Giant cell interstitial pneumonia (GIP) is distinctive rare pneumoconiosis most frequently found in workers exposed to metals, primarily cobalt tungsten carbide. The pathologic picture considered virtually pathognomonic for although this dogma...
RATIONALE: Preliminary studies have shown varied outcomes when comparing Acute Respiratory Distress Syndrome (ARDS) caused by Coronavirus Disease 2019 (COVID-19) versus “Classic” ARDS. The aim of this study was to compare patient characteristics and outcome ARDS before during COVID-19 pandemic. METHODS: We conducted a single center retrospective cohort at 3 hospitals sites Montefiore Medical Center pre-COVID respiratory failure from 2017 2018 COVID March 2020 May 2020. identified having...
Many patients admitted to intensive care units (ICUs) are at high risk of dying. We hypothesize that focused training sessions for ICU providers by palliative (PC) certified experts will decrease aggressive medical interventions the end life. designed and implemented a 6-session PC program in communication skills goals (GOC) meetings teams, including house staff, critical fellows, attendings. then reviewed charts treated before after intervention. Forty-nine 177 (28%) 63 173 (38%) were...
Adipose tissue inflammation and fibrosis appear to be mediated by adipocytes contribute insulin resistance. Since vitamin D (25(OH)D) has anti-inflammatory anti-fibrotic effects, expression of its receptor in macrophages suggests that 25(OH)D signaling could mediate paracrine effects within adipose improve We performed a randomized, double-blinded placebo-controlled trial examine the repleting 25(OH)D-deficient (&lt;20 ng/ml), resistant, overweight-to-obese humans (n=19). repletion...
You, Jee Young; Gulani, Perminder; Para, Kiran; Ligasaputri, Lie Dinah; Salgunan, Reka; Kavanagh, Elizabeth Author Information
Abstract Background Our understanding of changes in hemodynamics cirrhotic patients with sepsis and septic shock its impact on outcomes remains limited. study aims to investigate differences hemodynamic profiles using echocardiography between without cirrhosis. Methods This is a single-center, retrospective echocardiogram within 3 days medical intensive care unit (MICU) admission. We compared baseline characteristics, echocardiographic parameters, A propensity score-matched case-control...