A5101971599- Lung Cancer Treatments and Mutations
- Ferroptosis and cancer prognosis
- Immunotherapy and Immune Responses
- Erythrocyte Function and Pathophysiology
- RNA modifications and cancer
- Lung Cancer Research Studies
- Nuclear Receptors and Signaling
- Titanium Alloys Microstructure and Properties
- Breast Lesions and Carcinomas
- Bone Tissue Engineering Materials
- Pharmacological Effects of Natural Compounds
- Metal and Thin Film Mechanics
- Genomics, phytochemicals, and oxidative stress
- Breast Cancer Treatment Studies
- Cancer-related molecular mechanisms research
- Phagocytosis and Immune Regulation
- interferon and immune responses
- Wnt/β-catenin signaling in development and cancer
- Cancer Immunotherapy and Biomarkers
- Breast Implant and Reconstruction
- Microbial Natural Products and Biosynthesis
- Lymphatic System and Diseases
- Bioactive Compounds and Antitumor Agents
- Kruppel-like factors research
- Lung Cancer Diagnosis and Treatment
Jinggangshan University
2025
Shanghai University of Traditional Chinese Medicine
2019-2023
University of Michigan
2023
Nanjing Medical University
2020
Chinese Academy of Medical Sciences & Peking Union Medical College
2007
The University of Sydney
2007
Abstract Background CD47, the integrin-related protein, plays an important role in immune resistance and escape of tumor cells. Antibodies blocking CD47/SIRPα signal pathway can effectively stimulate macrophage-mediated phagocytosis cells, which becomes a promising approach for immunotherapy. Nanobodies (Nbs) derived from camelid animals are emerging as new force antibody therapy. Results HuNb1-IgG4, innovative anti-CD47 nanobody, was developed with high affinity specificity. It enhanced...
Objective . This study was aimed at investigating the prognostic significance of Baculoviral IAP repeat containing 5 (BIRC5) in lung adenocarcinoma (LAD) lacking EGFR, KRAS, and ALK mutations (triple-negative (TN) adenocarcinomas). Methods The gene expression profiles were obtained from Gene Expression Omnibus (GEO). identification differentially expressed genes (DEGs) performed by GeneSpring GX. set enrichment analysis (GSEA) used to execute ontology function pathway analysis. protein...
The ability to predict axillary lymph node involvement in breast cancer patients the preoperative setting is invaluable. This study provides a simple set of formulae enable clinicians make informed decisions management screen-detected cancer. tumor pathology reports were obtained all 4,585 women identified between 1996 and 1999 New South Wales (NSW) with T1 or T2 by statewide co-ordinated screening service (BreastScreen NSW). Equations predicting positivity calculated linear regression...
Chinese herbal Fu‐Zheng‐Qu‐Xie (FZQX) prescription has been found to improve the immune function and survival of patients with early‐stage lung cancer. However, therapeutic efficacy needs be evaluated objectively, precise mechanism remains unclear. In present study, a double‐center, prospective cohort study was carried out assess clinical FZQX in preventing recurrence metastasis postoperative adenocarcinoma. Our results indicated that could significantly reduce 3‐year rate life quality....
Yupingfengsan (玉屏风散) is a classical traditional Chinese formulae with proven therapeutic effect on the disease of respiratory system. However, its action mechanism remains obscure for lung adenocarcinoma (LAD). This study aimed to investigate potential target genes and in treatment LAD. chemical ingredients related targets were predicted by public databases. Differential expression LAD obtained from The Cancer Genome Atlas (TCGA) database. Gene set enrichment analysis (GSEA) was used execute...
Abstract Head and neck squamous cell carcinoma (HNSCC) are immunosuppressed solid tumors often diagnosed at advanced stages of the disease. Most HNSCC patients have a history oral epithelial dysplasia; however, there limited diagnostic criteria used to determine which lesions will progress cancer. There is an unmet clinical need what cellular events occur during tumor initiation that enables anti-tumor immune evasion heightened disease activity. Amplification SOX2, transcription factor...