A5062954908- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Privacy-Preserving Technologies in Data
- Cardiac electrophysiology and arrhythmias
- Cryptography and Data Security
- Cardiac pacing and defibrillation studies
- Cloud Data Security Solutions
- Cardiovascular Function and Risk Factors
- Blockchain Technology Applications and Security
- Cardiac Imaging and Diagnostics
- Mitochondrial Function and Pathology
- Vehicular Ad Hoc Networks (VANETs)
- Cardiac Fibrosis and Remodeling
- Cardiac tumors and thrombi
- Nuclear Structure and Function
- Cardiac Valve Diseases and Treatments
- Blood properties and coagulation
- User Authentication and Security Systems
- Genetics, Aging, and Longevity in Model Organisms
- Combustion and Detonation Processes
- Advanced MRI Techniques and Applications
- Endoplasmic Reticulum Stress and Disease
- Diabetes Treatment and Management
- Viral Infections and Immunology Research
- Acute Myocardial Infarction Research
Ruijin Hospital
2018-2025
Shanghai Jiao Tong University
2018-2025
Qiqihar Medical University
2021
University of Electronic Science and Technology of China
2018-2019
This study aimed to evaluate the long-term efficacy and clinical outcomes of catheter ablation performed with cryoballoon (CRYO) in comparison robotic magnetic navigation (RMN) patients persistent atrial fibrillation (PersAF). A total 200 symptomatic PersAF were prospectively enrolled non-randomly assigned (1:1) CRYO or RMN guided-ablation group undergoing pulmonary vein isolation (PVI) additional linear if necessary then followed up over 5 years. The primary endpoint was freedom from...
Existing server-aided attribute-based signature (SA-ABS) to secure industrial Internet of Things (IIoT)-oriented applications raise challenges such as achieving collusion attack resilience and realizing expressive linear secret-sharing scheme (LSSS) access structures. In this paper, we positively address these by proposing a novel SA-ABS for IIoT. Distinct from the existing works in field, our protocol not only allows delegate heavy calculation both generation verification third-party...
It is a new trend in healthcare informatization construction to build the smart system by using Internet of Things (IoT) and cloud. This IoT-oriented cloud-assisted enables doctor monitor patient's health state respond paroxysmal diseases real time. Considering sensitivity privacy, it necessary encrypt cloud-stored data prevent semi-trusted cloud unauthorized users from accessing them. However, encrypted stored brings inconvenience retrieval for user. In addition, expensive computational...
The Internet of Vehicles (IoV) is expected to play a revolutionary role in improving users' driving experience and urban traffic governance. By widely absorbing emerging technologies including cloud computing, the future IoV evolution leading towards providing more flexible diversified data services. However, publicly accessible environment arouses user's concerns about leakage personal privacy. Despite some cryptographic solutions have been proposed, they still raise challenges on privacy,...
Abstract: Navitoclax, which is a type of senolytic drug, selectively eliminates senescent cells. This study aimed to evaluate the therapeutic potential navitoclax in treatment angiotensin II (Ang II)-induced heart failure mice. Navitoclax or vehicle was administrated mice with Ang II-induced failure. Cardiac function and electrophysiology were assessed before after administration navitoclax. remodeling, including morphological changes, fibrosis, inflammatory responses, analyzed myocardial...
Public key encryption with equality test (PKE-ET) enables anyone to perform equivalence between two messages encrypted under distinct public keys. Attribute-hiding predicate is a paradigm for that supports both attribute-hiding and fine-grained access control. In this paper, we first initialize the concept of (AH-PE-ET) by incorporating notions PKE-ET PE, then propose concrete AH-PE-ET scheme. Inheriting merits encryption, versatile control can be achieved such ciphertexts secret are,...
Abstract Background Early recurrence (ER) after catheter ablation for atrial fibrillation (AF) has been considered as a common phenomenon but its mechanism and implication in long-term outcome not fully elucidated. We aimed to clarify the relation between post-ablation inflammation ER cryoballoon (CBA) or radio-frequency (RFA) evaluate clinical significance of ER. Methods A total 154 patients with paroxysmal AF undergoing were consecutively recruited, including 90 RFA (RF group) 64 CBA (CB...
Atrial fibrillation (AF) is an age-related disease, while telomeres play a central role in aging. But the relationship between AF and telomere length (LTL) still controversial. This study aims to examine potential causal association LTL by using Mendelian randomization (MR).Bidirectional two-sample MR, expression protein quantitative trait loci (eQTL pQTL)-based MR were performed genetic variants from United Kingdom Biobank, FinnGen, meta-analysis study, which comprised nearly 1 million...
Introduction: Currently, numerous ablation techniques are available for atrial fibrillation (AF), in addition to manual radio frequency ablation. The aim of this prospective, non-randomized concurrent controlled trial was compare the mid-term efficacy and procedural outcomes persistent AF (PerAF) using cryoballoon (CB) robotic magnetic navigation (RMN). Methods: Two hundred PerAF patients were assigned, a 1:1 ratio, undergo catheter RMN (RMN group) or CB (CB group). primary endpoint freedom...
Dilated cardiomyopathy (DCM) is associated with high mortality despite advanced therapies. The
Attribute-based signature (ABS) can provide fine-grained and anonymous authentication for the Industrial Internet of Things (IIoT). However, key exposure computational performance bottleneck resource-constrained devices raise a challenge to IIoT-oriented ABS schemes. To confront above challenge, this article proposes an intrusion-resilient server-aided (IR-SA-ABS) scheme. This scheme designs periodically update signing with assistance helper device, is refreshed multiple rounds aperiodically...
The objective of this study was to assess the impact steerable sheaths compared with fixed-curve on procedural outcomes atrial fibrillation (AF) ablation guided by robotic magnetic navigation (RMN).In retrospective case-control study, 110 patients scheduled for AF catheter were enrolled and divided into two groups. Fifty-five (paroxysmal, 70%) treated RMN-guided utilizing a sheath another 55 ablated RMN using sheath. Clinical characteristics similar between Compared group, group procedure...
Abstract Emerin is an inner nuclear envelope protein encoded by the EMD gene, mutations in which cause Emery–Dreifuss muscular dystrophy type 1 (EDMD1). Cardiac involvement has become a major threat to patients with EDMD1; however, cardiovascular phenotype spectrums of emerinopathy and mechanisms emerin regulates cardiac pathophysiology remain unclear. Here, we identified novel nonsense mutation (c.C57G, p.Y19X) gene Han Chinese family through high‐throughput sequencing. Two members were...
Autonomous vehicle platoons are emerging as a promising solution to modern urban governance challenges, such traffic congestion, air pollution, and fuel waste. As data-driven paradigm, ensuring secure data sharing is key challenge for autonomous platoon applications. However, existing research on of vehicles suffers from practical weaknesses privacy leakage, lack flexible source identification, inefficiency. Motivated by that, this paper first proposes the LFBA scheme, which fine-grained...
Myeloperoxidase (MPO), released by activated neutrophils, is significantly increased in atrial fibrillation (AF). MPO may play a role the progression of and further involved AF recurrence after catheter ablation. We compared plasma levels paroxysmal persistent explored their ablation.Plasma were measured consecutive patients with (n = 225) 106). Samples collected from femoral vein during ablation all included followed up to (56.31 [40.33-73.51] vs. 64.11 [48.65-81.11] ng/ml, p < 0.001)....
Abstract Background Remote magnetic navigation (RMN)‐guided ablation has become an inspiring method of catheter for tachyarrhythmias. Hypothesis Data from a large‐scale single center may provide further insight into the safety and learning curve RMN‐guided ablation. Methods A total 1003 procedures using RMN conditions including supraventricular ventricular tachycardia, atrial tachyarrhythmias, premature contraction/ventricular tachycardia (PVC/VT) were retrospectively analyzed registry....
There are controversies on the pathophysiological alteration in patients with atrial fibrillation (AF) undergoing pulmonary vein isolation using different energy sources.We evaluated changes plasma proteins acute phase post-ablation receiving cryoballoon ablation, radiofrequency balloon or ablation.Blood samples from eight healthy controls and 24 AF were taken day of admission, 1, 2 analyzed by Olink proximity extension assay. Proteins identified performed enrichment analysis....
Data comparing dabigatran with rivaroxaban regarding the resolution of left atrial/left atrial appendage (LA/LAA) thrombus in patients nonvalvular fibrillation (AF) are scarce. This study aimed to compare efficacy and safety vs LA/LAA AF.This retrospective enrolled AF scheduled undergo catheter ablation or cardioversion Shanghai Ruijin Hospital between January 2014 2019. Altogether, 34 detected by transesophageal echocardiography (TEE) were enrolled. Among them, 12 treated 150 mg bid other...
Background: Left atrial spontaneous echo contrast (LASEC) can be detected by transesophageal echocardiography (TEE) before the catheter ablation of fibrillation (AF), especially in patients with left (LA) dilation. Whether LASEC has prognostic value predicting procedure outcomes an enlarged atrium is unknown. The implications AF LA dilation will evaluated this study. Methods: scheduled to undergo Ruijin Hospital, Shanghai, China, between January 2018 and June 2020 were screened for...
Catheter ablation of frequent para-Hisian premature ventricular contractions (PH-PVCs) is considered to be challenging. The purpose this study was evaluate the strategy, potential technical advantages, and clinical outcomes remote magnetic navigation (RMN) in PH-PVCs.Fifteen consecutive patients with PH-PVCs were included study. Electrical mapping initially performed right septum by manipulating RMN catheter a "U-curve." In case no optimal site or failure, directed left (LV) through...