A5021238900- Respiratory viral infections research
- Influenza Virus Research Studies
- Risk and Safety Analysis
- Virology and Viral Diseases
- SARS-CoV-2 and COVID-19 Research
- Cervical Cancer and HPV Research
- Viral gastroenteritis research and epidemiology
- Hepatitis C virus research
- Animal Disease Management and Epidemiology
- Nuclear Engineering Thermal-Hydraulics
- Nuclear reactor physics and engineering
- Hepatitis B Virus Studies
- Genital Health and Disease
- Graphite, nuclear technology, radiation studies
- Vaccine Coverage and Hesitancy
- Parvovirus B19 Infection Studies
- SARS-CoV-2 detection and testing
- COVID-19 Clinical Research Studies
- HIV Research and Treatment
- Fault Detection and Control Systems
- Immunodeficiency and Autoimmune Disorders
- Pneumonia and Respiratory Infections
- Disaster Management and Resilience
- Insurance and Financial Risk Management
- Dermatological and COVID-19 studies
University of Milan
2016-2025
Centre for Multidisciplinary Research in Health Science
2023-2024
Department of Medical Sciences
2014-2023
Azienda Socio Sanitaria Territoriale Lariana
2023
Aziende Socio Sanitarie Territoriale dei Sette Laghi
2023
Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini"
2023
Directorate of Health
2023
Regione Lombardia
2023
Azienda Socio Sanitaria Territoriale della Valtellina e Alto Lario
2023
Ospedale dei Bambini Vittore Buzzi
2022
Since 2009 pandemic, international health authorities recommended monitoring severe and complicated cases of respiratory disease, that is, acute infection (SARI) distress syndrome (ARDS). We evaluated the proportion SARI/ARDS deaths due to influenza A(H1N1)pdm09 impact other viruses during pandemic postpandemic period (2009–2011) in northern Italy; additionally we searched for unknown those which diagnosis remained negative. 206 samples were collected from analyzed by real-time RT-PCR/PCR...
Abstract We identified severe acute respiratory syndrome coronavirus 2 RNA in an oropharyngeal swab specimen collected from a child with suspected measles early December 2019, ≈3 months before the first disease case Italy. This finding expands our knowledge on timing and mapping of novel transmission pathways.
Background/Aim: Chronic kidney disease (CKD), primarily caused by diabetes, predisposes patients to a high risk of systemic complications, including vascular ulcers. This study aimed evaluate the impact arterial ulcers in with CKD, particular attention predisposing factors diabetes and prevention strategies. Methods: A narrative literature review was conducted, adopting Scale for Assessment Narrative Review Articles (SANRA), using databases such as PubMed, CINAHL, Embase, Cochrane Library,...
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Since late 2023, the Metropolitan City of Milan and surrounding areas (northern Italy) have been experiencing a resurgence measles, with most cases detected starting from January 2024. During this brief period, we observed measles in travellers endemic areas, participants international events, vaccinees healthcare workers. Indigenous also identified. Even though not yet identified large disruptive outbreaks, strengthening surveillance vaccination activities is pivotal to help limit impact spread.
Objective: It is unclear whether the ability to respond vaccines restored by antiretroviral therapy. We evaluated influenza-specific immune responses elicited a virosomal vaccine in HIV-infected children on long-term successful highly active therapy (HAART). Methods: This was an observational, prospective, open-label study enrolling 24 HIV-infected, HAART-treated (85 months' mean exposure), vaccine-naive (median age = 11.9 years) and 14 age- gender-matched healthy controls. Mean CD4 T-cell...
This work presents a new general methodology called Event Sequences and Consequence Spectrum, which is the result of synthesis between Response Surface Methodology for simulation system physical behavior Logical Analytical generation logical structures in reliability studies.The connection to aspects allows investigation physically possible accident temporal sequences, their dynamic consequence spectrum, associated probability occurrence.An exemplificative application derived from...
Despite the existence of an effective live-attenuated vaccine, measles can appear in vaccinated individuals. We investigated breakthrough cases identified during our surveillance activities within measles/rubella network (MoRoNet) Milan and surrounding areas (Northern Italy). Between 2017 2021, we confirmed virus (genotypes B3 or D8) infections 653 patients 51 these (7.8%) were vaccinees. Among individuals whose serum was available, a secondary failure evidenced 69.4% (25/36) while 11...
COVID-19, a recently emerged disease caused by SARS-CoV-2 infection, can present with different degrees of severity and large variety signs symptoms. The oral manifestations COVID-19 often involve the tongue, loss taste being one most common symptoms disease. This study aimed to detect RNA assess possible morphological immunopathological alterations in lingual tissue patients who died history infection. Sixteen cadavers from 8 positive (COVID-19+) negative (COVID-19-) subjects provided 16...
The Cuneo Plain (Piedmont, NW Italy), like the whole Po Plain, is characterized by intense agricultural activities that heavily rely on seasonal water availability, which now challenged climate crisis. In study area, groundwater resources represent a great tool to buffer temporary scarcity and mitigate drought risk. connection between irrigation network unconfined aquifer made available historical drainage trenches, known as fontanili. They were constructed starting from 11th century with...
An outbreak of measles virus genotype B3 is ongoing in Milan and surrounding areas since February 2025, with 27 cases identified 32 laboratory-confirmed cases. Most were locally acquired young adults. Phylogenetic analysis indicated the presence a unique lineage closely related to strains circulating Morocco. The lack epidemiological links between several affected individuals suggests case numbers are being underestimated. continuous transmission raises concerns about potential...
Abstract The immunogenicity of an anti‐influenza vaccine was assessed in 409 former intravenous drug user volunteers and its effect on the levels HIV‐1 RNA, proviral DNA CD4+ lymphocyte counts a subset HIV‐1‐positive subjects measured. individuals (n = 72) were divided into three groups basis their counts, while 337 HIV‐1‐negative participants allocated group four. Haemagglutination inhibiting (HI) responses varied from 45.8 to 70% significantly higher four (80.7% H1N1 strain, 81.6% H3N2 83%...
The dynamic logical analytical methodology (DYLAM) modeling and analysis techniques are discussed, its principal features compared with those of the fault tree technique for reliability analysis. study is performed reference to auxiliary feedwater system a 1300-MW(electric) pressurized water reactor plant. results reveal advantages that can be obtained by processes DYLAM, especially when dealing operator interventions in incident control mitigation.
Abstract. A fault system made of two segments or asperities subject to a constant strain rate is considered. The modelled as discrete dynamical blocks coupled by Maxwell spring dashpot element and pulled at velocity on rough plane. long-term behaviour the studied calculating orbits in phase space. model shows role viscoelastic relaxation Earth's crust controlling occurrence times earthquakes. If coupling present, earthquakes are anticipated delayed with respect elastic case. limit cycles...