A5015631001- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Cardiac electrophysiology and arrhythmias
- Coronary Interventions and Diagnostics
- Peripheral Artery Disease Management
- Vascular Procedures and Complications
- Cardiac pacing and defibrillation studies
- Cardiac Ischemia and Reperfusion
- Venous Thromboembolism Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Ion channel regulation and function
- Acute Myocardial Infarction Research
- Cardiac Fibrosis and Remodeling
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Valve Diseases and Treatments
Universidade Federal de São Paulo
2004-2025
Hospital Israelita Albert Einstein
2017
Fundação de Apoio à Universidade Federal de São Paulo
2010
To correlate the importance of ankle-brachial index in terms cardiovascular morbimortality and extent coronary arterial disease amongst elderly patients without clinical manifestations lower limb peripheral disease.We analyzed prospective data from 100 over 65 years age with disease, as confirmed by angiography, 70% stenosis at least one sub-epicardial artery. We measured immediately after a value <0.9 was used to diagnose disease.The patients' average 77.4 years. The most prevalent risk...
Background: In the elderly, ankle-brachial index (ABI) has greater than 90% sensitivity and specificity for peripheral artery disease identification. A well-known relation exists between number of diseased coronary vessels. Yet, other anatomical characteristics have important impacts on type treatment prognosis. Purpose: To determine ABI complexity disease, by different classifications. Methods: This study was a prospective analysis patients ≥65 years old who were undergoing elective...
Background: There is little research in the efficacy and safety of a pharmaco-invasive strategy (PIS) patients ≥ 75 years versus < age. We aimed to evaluate compare influence advanced age on risk death major adverse cardiac events (MACE) undergoing PIS. Methods: Between January 2010 November 2016, 14 municipal emergency rooms São Paulo, Brazil, used full-dose tenecteplase treat with STEMI as part for local network implementation. Results: A total 1852 PIS were evaluated, which 160 (9%)...
Summary 1. A novel inexpensive murine model of oral administration digitoxin (100 µg/kg per day) added to routine chow is described. 2. Serum levels achieved after ( n = 5; 116 ± 14 ng/mL) and subcutaneous 124 11 were similar. 3. significant increase in the maximal left ventricular pressure rise treated 9) compared with control 6) rats (dP/dt: 8956 233 vs 7980 234 mmHg/s, respectively; P 0.01) characterized positive inotropic action digitoxin. In addition, no differences observed regard...
After the report that there was no statistical significance in general mortality of DIG study, indication digoxin treatment regimens for congestive heart failure (CHF) drastically decreased. Post hoc studies reassessed study data, indicated an aspect not considered this multicenter has a critical influence on prognosis patients: serum levels digoxin. Regarding those received placebo, and hospitalization were decreased patients with level < 0.9 ng/ml. At first assessed digitalis experimental...
Depois da divulgação de que não houve significância estatística na mortalidade geral do estudo DIG, a indicação dos digitálicos nos esquemas tratamento insuficiência cardíaca congestiva (ICC) reduziu drasticamente. Estudos post hoc, reavaliaram os dados indicaram um aspecto considerado neste ensaio multicêntrico exerce influência decisiva no prognóstico pacientes: concentração sérica digoxina. Em relação àqueles receberam placebo, e hospitalização foram reduzidas em pacientes com digoxina...