A5068694485- Asphalt Pavement Performance Evaluation
- Concrete and Cement Materials Research
- Innovative concrete reinforcement materials
- Infrastructure Maintenance and Monitoring
- Smart Materials for Construction
- Extracellular vesicles in disease
- Magnesium Oxide Properties and Applications
- Polymer composites and self-healing
- Nanoplatforms for cancer theranostics
- Polymer Nanocomposites and Properties
- Surface Modification and Superhydrophobicity
- Concrete Corrosion and Durability
- Innovations in Concrete and Construction Materials
- Geotechnical Engineering and Underground Structures
- Genomics, phytochemicals, and oxidative stress
- Ubiquitin and proteasome pathways
- Epoxy Resin Curing Processes
- Grouting, Rheology, and Soil Mechanics
- Nanoparticle-Based Drug Delivery
- High voltage insulation and dielectric phenomena
- Advanced Energy Technologies and Civil Engineering Innovations
- Climate change and permafrost
- Phase Change Materials Research
- Histone Deacetylase Inhibitors Research
- Material Properties and Applications
Chang'an University
2018-2025
Jinan University
2024
Southern Medical University
2022-2024
Ministry of Transport
2020
Shanghai Jiao Tong University
2019-2020
Beijing Obstetrics and Gynecology Hospital
2019-2020
Capital Medical University
2019-2020
Dalian Medical University
2019
Abstract Multidrug resistance remains a great challenge for cancer chemotherapy. Herein, biomimetic drug delivery system based on lemon‐derived extracellular vesicles (EVs) nanodrugs (marked with heparin‐cRGD‐EVs‐doxorubicin (HRED)) is demonstrated, achieving highly efficient overcoming multidrug resistance. The HRED fabricated by modifying functional heparin‐cRGD (HR) onto the surface of EVs and then loading doxorubicin (DOX). obtained enable to effectively enter DOX‐resistant cells...
Abstract Existing solid‐nanoparticle‐based drug delivery systems remain a great challenge for glioblastoma chemotherapy due to their poor capacities in crossing the blood–brain barrier/blood–brain tumor barrier (BBB/BBTB). Herein, fruit‐derived extracellular‐vesicle (EV)‐engineered structural droplet drugs (ESDDs) are demonstrated by programming self‐assembly of EVs at DOX@squalene–PBS interface, greatly enhancing antitumor efficacy against glioblastoma. The ESDDs experience flexible via...
Extracellular vesicles (EVs) have recently received much attention about the application of drug carriers due to their desirable properties such as nano-size, biocompatibility, and high stability. Herein, we demonstrate orange-derived extracellular (OEV) nanodrugs (DN@OEV) by modifying cRGD-targeted doxorubicin (DOX) nanoparticles (DN) onto surface OEV, enabling significantly enhancing tumor accumulation penetration, thereby efficiently inhibiting growth ovarian cancer. The obtained DN@OEV...
Waterborne epoxy modified emulsified asphalt (EMEA) has the shortcomings of insufficient toughness and poor aging resistance, which limits its application low-carbon cold-paving technology in plateau zones. To obtain a cold-mix binder with excellent performance, waterborne polyurethane (WPU) was utilized to modify EMEA this work. Properties, modification mechanism, action process, environmental benefits, cost-benefit composite-modified (CMEA) were analyzed. Results show that CMEA had good...
Recycled asphalt pavement (RAP) can be used in highway engineering again by cold recycled technology. Due to the aged on surface of RAP, some problems such as poor adhesion between emulsified and RAP low properties recycling mixture are easy occur. This work aims at analyzing aging degree from improving modifying characteristics RAP. In this work, a new device was designed delaminate off The different layers studied then physical molecular weight distribution. Slurry hydrated lime (Ca(OH) 2...
The aging of bitumen seriously affects the service life bituminous pavements. At present, there are many related researches on aging, but most them focus endured in indoor surroundings and conditions. Therefore, conclusions obtained cannot reflect actual changes pavements service. In order to study comprehensive process mechanism under influence service, we studied bridge deck, traffic lane, ramp with pavement structures samples from core different were characterized by gel permeation...