A5071663169- Biochemical Analysis and Sensing Techniques
- Water Treatment and Disinfection
- Legionella and Acanthamoeba research
- Olfactory and Sensory Function Studies
- Advanced Chemical Sensor Technologies
- Vibrio bacteria research studies
- Bacterial biofilms and quorum sensing
Saarland University
2022
Al-Quds University
2020
Constant exposure of the airways to inhaled pathogens requires efficient early immune responses protecting against infections. How bacteria on epithelial surface are detected and first-line protective mechanisms initiated not well understood. We have recently shown that tracheal brush cells (BCs) express functional taste receptors. Here we report bitter signaling in murine BCs induces neurogenic inflammation. demonstrate BC stimulates adjacent sensory nerve endings trachea release...
Mucociliary clearance is a primary defence mechanism of the airways consisting two components, ciliary beating and transepithelial ion transport (ISC). Specialised chemosensory cholinergic epithelial cells, named brush cells (BC), are involved in regulating various physiological immunological processes. However, it remains unclear if BC influence ISC. In murine tracheae, denatonium, taste receptor agonist, reduced basal ISC concentration-dependent manner (EC50 397 µM). The inhibition bitter...
The West Bank can be considered as a high-risk area for Legionella prevalence in drinking water due to high ambient temperature, intermittent supply, frequent pressure loss, and storage of roof containers. To assess occurrence species, especially L. pneumophila, the Bank, distribution systems eight hospitals were sampled over period 2.3 years covering seasonal cycle major geographic regions. gain insight into potential environmental drivers, set physico-chemical microbiological parameters...
The West Bank can be considered a high-risk area for Legionnaires’ disease (LD) due to its hot climate, intermittent water supply and roof storage of drinking water. Legionella, mostly L. pneumophila, are responsible LD, severe, community-acquired nosocomial pneumonia. To date, no extensive assessment Legionella spp pneumophila using cultivation in combination with molecular approaches the has been published. Two years environmental surveillance biofilms distribution systems (DWDS) eight...