Introduction During the pandemic, overweight and obese adolescents were at a higher risk of COVID-19 infection. Indonesia’s government has implemented prevention programmes immunisation; however, rise in SARS-CoV-2 infections among is exacerbated by low-quality diet lifestyle habits. Also, vaccine programme not prioritised this population. To address this, solution involves providing probiotics counselling on healthy habits to improve immunity. Therefore, we designed protocol for randomised...

Hyperacidity causes gastric injury, and in severe situations, ulcer could develop. The growth factors known asthe basic fibroblast factor (bFGF) the epidermal (EGF) have been recognized to promoteulcer healing. Fucoidan is extracted from a brown seaweed of Okinawa called Mozuku or Cladosiphon okamuranus.Fucoidan effective for healing ulcers by inducing epithelial cells produce factors. aimof this study explore efficacy fucoidan patient who suffered ulcer. A randomized control trialdouble...

Ulcerative colitis (UC) is one of the 2 major disorders in pediatric inflammatory bowel disease (IBD). Differentiating IBD at an early stage remains difficult, and abdominal imaging precise investigations are crucial. A 2-year-old girl was referred to emergency department after experiencing colicky pain for 1 month. She had bloody stool 4 days before admission with frequency about 1-2 times per day. also experienced anorexia, nausea, weight loss. From Abdominal CT-Scan contrast, multiple...

Background Acute lymphoblastic leukemia (ALL) is the most common malignancy in children and adolescents. Febrile Neutropenia (FN) a medical emergency on ALL that often leads to death. Nutrition status assessment patient important because malnutrition can reduce tolerance of chemotherapy, increase incidence infection decrease survival rate.
 Objectives To assess as risk factor for FN with ALL.
 Methods This case-control study was performed at Sardjito Hospital, Yogyakarta patients...

Information regarding functional gastrointestinal disorders (FGIDs) in infants is currently lacking Indonesia. This study aimed to describe the prevalence and risk factors of FGIDs aged 6 weeks 4 months Indonesia.This cross-sectional 433 was conducted between September 2018 February 2020. on collected using Infant Gastrointestinal Symptom Questionnaire Feeding Practice Gut Comfort Questionnaire. Adapted Rome IV criteria were used define FGIDs.The regurgitation 26.3%; 16.8% presented...

Background: Meckel diverticulum (MD) is the most common congenital anomaly of intestines, with an incidence 2% general population. It can present as various clinical features complications and be life threatening if diagnosis delayed treatment late. Case Presentation: We report three pediatric cases complicated MD: one female presented small-bowel obstruction, male peritonitis, severe iron-deficiency anemia, without gross gastrointestinal bleeding nor any ectopic gastric mucosa. All patients...

Despite safe and effective WHO prequalified rotavirus vaccines, at least 84 million children remain unvaccinated. A birth dose schedule of the RV3-BB vaccine was reported to be highly efficacious against severe disease in Indonesian infants is under further development PT Bio Farma, Indonesia. The aim develop a starting from that could improve implementation, safety, effectiveness vaccines. multi-site phase I study human neonatal RV3 (Bio Farma) adults, children, neonates Indonesia April...

Background In developing countries, acute watery diarrhea isa common cause of morbidity and mortality in children. Givingsynbiotics or probiotics may decrease the severity diarrhea.Objective To compare efficacy synbiotics probioticsin decreasing frequency diarrhea, shortening duration,and increasing patient body weight.Methods This was a double􀀷blind, randomized clinical trial tocompare effects synbiotic vs probiotic treatment childrenaged 6􀀷59 months v.ith diarrhea. study wasperformed from...

Gastric stricture due to corrosive ingestion is a rare cause of obstruction in the upper gastrointestinal tract children. However, only few reports highlight management gastric antrum and pylorus, i.e. outlet (GOO) ingestion, particularly We report 1-year-old male who presented with chief complaints abdominal pain profuse vomiting after accidentally ingesting sulfuric acid one month prior. On physical examination, minimal epigastric distension was found. Endoscopic examination showed...

Background Epilepsy affects 1% of children worldwide. The highest incidence is in the first year life, and perinatal factors, such as hypoxic-ischemic injury, infection, cortical malformation may play etiologic roles. Breast milk contains optimal nutrients for human brain early life. Breastfeeding has been associated with lower risk infections, better cognitive psychomotor development. However, role breastfeeding preventing childhood epilepsy remains unclear. Objective To evaluate an...

Latar belakang. Perdarahan saluran cerna pada anak merupakan salah satu tanda bahaya sehingga diagnosis dan pengobatan dini sangat penting.Tujuan. Mengetahui etiologi temuan klinis perdarahan yang dirawat di RSUP Dr. Sardjito.Metode. Penelitian retrospektif menggunakan rekam medis pasien berusia kurang dari 18 tahun menjalani endoskopi kolonoskopi karena Januari 2009 hingga Juni 2015. Data tidak lengkap diikutkan sertakan dalam penelitian.Hasil. Dari 55 memenuhi syarat, terdapat 27 (49%)...

Background Epilepsy affects 1% of children worldwide.The highest incidence is in the first year life, and perinatal factors, such as hypoxic-ischemic injury, infection, cortical malformation may play etiologic roles.Breast milk contains optimal nutrients for human brain early life.Breastfeeding has been associated with lower risk infections, better cognitive psychomotor development.However, role breastfeeding preventing childhood epilepsy remains unclear. ObjectiveTo evaluate an association...

Introduction: Diarrhea is still a leading cause of death in the world children, especially children under 5 years. contagious disease with relatively high morbidity and mortality rates. Rotavirus diarrhea very important public health problem both developed developing countries. Parents' knowledge one causes due to parents' ignorance diarrhea, how transmitted prevent diarrhea.Methods: This explanatory mixed qantitative-qualitative method quasi experimental design study determine effect...

Latar belakang. Hingga saat ini, diare masih menjadi salah satu masalah kesehatan dunia, terutama di negara berkembang, termasuk Indonesia. Salah komplikasi lanjutan dari dehidrasi pada adalah gangguan elektrolit serum. Tujuan. Untuk mengetahui prevalensi serum pasien dengan serta karakteristik klinis dan hubungan antara derajat terhadap serum.Metode. Penelitian retrospektif rancangan cross sectional menggunakan data rekam medis. Perbedaan dianalisis uji Chi-square.Hasil. Jumlah yang...

Latar belakang. Leukemia limfoblastik akut (LLA) merupakan keganasan yang sering ditemukan pada anak dan remaja. Demam neutropeni (DN) kedaruratan medik LLA menyebabkan kematian.Tujuan. Mengetahui angka kejadian kematian DN selama terapi fase induksi.Metode. Penelitian deskriptif dengan disain potong lintang. Subjek adalah pasien kurun Januari 2013 hingga Desember 2015, usia 1 bulan 18 tahun tengah menjalani induksi. Neutropeni ditegakkan jumlah neutrofil absolut <1.500/mmk. Pengambilan...

Latar belakang. Prevalensi infeksi Helicobacter pylori (H. pylori) di berbagai wilayah bervariasi. Infeksi H. pada anak umumnya tidak menunjukkan gejala khas, tetapi dapat mengakibatkan komplikasi. Tujuan. Melihat prevalensi dan dengan gastrointestinal Yogyakarta.Metode. Data dikumpulkan dari pasien keluhan dispepsia, nyeri perut berulang, muntah buang air besar disertai darah yang dicurigai mengalami RSUP. Dr. Sardjito, Yogyakarta. Diagnosis ditegakkan pemeriksaan endoskopi histologi.Hasil....

Latar belakang. Konstipasi adalah kelainan yang sering terjadi dan menimbulkan masalah serius padabayi anak. Penyebab konstipasi dapat dibagi menjadi penyebab non organik/fungsional penyebaborganik. Tatalaksana anak dengan fungsional meliputi beberapa langkah, 1) edukasi, 2) pengeluaranfeses/disimpaksi, 3) fase pemeliharaan. Pada disimpaksi pemeliharaan diperlukan laksansia secara oralataupun rektal.Tujuan. Membandingkan oral (Laktulose) per rektal (phosphate enema) pada anakdengan kronis,...

Background Diarrhea is the major cause of morbidity and mortalityin children. Probiotics can decrease frequency durationof diarrhea. There are two types probiotics, live tyndallized.Tyndallized probiotics have been stetilized, so they unable to produceactive metabolites, but may an effect on human immunity.Objective To evaluate effectiveness supplementing WHOstandard therapy with tyndallized in children withacute, watery diarrhea.Methods We performed a randomized, single-blind,...

Choledochal cyst (CC) is a morphological malformation characterized by dilatations of the biliary tree that might present later with clinical symptoms, including jaundice, abdominal pain or pancreatitis.Here, we reported 10-month-old female infant CC presenting jaundice and right upper quadrant mass who was malnourished following surgical excision retroperitoneal teratoma one month ago. Laboratory findings were total bilirubin 14.17 mg/dL, direct 12.24 gamma glutamyl transferase 1157 U/L,...

Background Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy. Initial treatment delay a modifiable prognostic factor that significantly affects overall survival (OS) and event-free (EFS) of ALL in high-income countries. Nevertheless, effect delayed initial low-middle income countries had not been determined.
 Objective To analyze relationships between with children ALL.
 Methods A retrospective study was conducted aged < 18 years newly diagnosed L1 L2...