- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Lung Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Pleural and Pulmonary Diseases
- Cancer, Hypoxia, and Metabolism
- Advanced Radiotherapy Techniques
- Economic and Financial Impacts of Cancer
- Aortic aneurysm repair treatments
- Trauma and Emergency Care Studies
- Tracheal and airway disorders
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Medical Imaging and Pathology Studies
- Infectious Aortic and Vascular Conditions
- Occupational and environmental lung diseases
- RNA modifications and cancer
- Pancreatic and Hepatic Oncology Research
- Congenital Diaphragmatic Hernia Studies
- Ultrasound in Clinical Applications
- Mechanical Circulatory Support Devices
- Surgical Simulation and Training
- Transplantation: Methods and Outcomes
- Respiratory Support and Mechanisms
Southern Ohio Medical Center
2017-2024
University Hospitals of Leicester NHS Trust
2024
University of Kentucky
1989-2019
Markey Cancer Center
2014-2019
Hôpital Européen
2019
Hôpital Européen Georges-Pompidou
2019
Conquest Hospital
2017
Albany Medical Center Hospital
2017
American College of Surgeons
2014-2016
Orlando Health
2015
<h3>Importance</h3> A minority of patients who experience postoperative complications die (failure to rescue). Understanding the preoperative factors that lead failure rescue helps surgeons predict and avoid operative mortality. <h3>Objective</h3> To provide a mechanism for identifying high-risk group with are at substantially increased risk rescue. <h3>Design, Setting, Patients</h3> Observational study evaluating in entered into American College Surgeons National Surgical Quality...
Base deficit (BD) and lactic acid (LA) are accepted markers of hypoperfusion predictors outcome in the trauma patient we aim to assess value these triage elderly with “normal” vital signs. Patients older than age 65 who presented between 1997 2004 but did not have isolated head injuries were included. Three groups established: normal, occult (OH), shock. Outcome measures included mortality, hospital length stay, intensive care unit discharge disposition. One hundred six patients analysis had...
Cancer and stromal cell metabolism is important for understanding tumor development, which highly depends on the microenvironment (TME). Cell or animal models cannot recapitulate human TME. We have developed an ex vivo paired cancerous (CA) noncancerous (NC) lung tissue approach to explore cancer in native This enabled full control of experimental parameters acquisition individual patient's target response therapeutic agents while eliminating interferences from genetic physiological...
Surgical resection of the esophagus remains mainstay treatment for esophageal cancer. However, esophagectomy is associated with significant morbidity and mortality in postoperative period. We have recently altered our practice pattern to include minimally invasive (MIE) as approach choice hope minimizing this procedure. In retrospective analysis, we compare outcomes first year performing MIE previous 3 years open (OE) at a single teaching hospital. Sixty-five patients underwent between June...
Background Coronary artery disease has a high prevalence among lung transplant recipients and historically been contraindication to at many institutions. In patients with mild-to-moderate coronary (Mod-CAD) undergoing transplant, outcomes are not well defined. Methods All who underwent pulmonary transplantation from January 1996 through November 2010 pretransplant angiogram were included in our study. Recipients of multivisceral, redo, lobar transplants those revascularization excluded....
e23157 Background: Precision medicine holds promise for improving cancer care, yet significant challenges persist in implementing multigene NGS testing and incorporating targeted therapies community settings. To better understand these issues, an implementation science framework was used to identify key barriers facilitators inform future QI projects. Methods: The study involved a retrospective review of biomarker patterns across three centers, coupled with stakeholder interviews process...
Video-assisted thoracoscopic (VATS) lobectomy is considered a promising surgical therapy for the diagnosis and treatment of non-small-cell lung carcinoma. The issue whether VATS superior to open thoracotomy remains controversial, however. We sought determine use diagnosing treating carcinoma would improve patient outcomes at our institution.A retrospective review electronic paper medical charts identified 109 consecutive operations all patients undergoing or performed University Kentucky...