A5083667072- Transplantation: Methods and Outcomes
- Mechanical Circulatory Support Devices
- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Pancreatic and Hepatic Oncology Research
- Tracheal and airway disorders
- Cardiac Valve Diseases and Treatments
- Gastric Cancer Management and Outcomes
- Lung Cancer Diagnosis and Treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Respiratory Support and Mechanisms
- Organ Donation and Transplantation
- Pneumocystis jirovecii pneumonia detection and treatment
- Congenital Heart Disease Studies
- Renal cell carcinoma treatment
- Gallbladder and Bile Duct Disorders
- Lung Cancer Treatments and Mutations
- Aortic Disease and Treatment Approaches
- Obstructive Sleep Apnea Research
- Colorectal Cancer Surgical Treatments
- Esophageal Cancer Research and Treatment
- Organ and Tissue Transplantation Research
- Colorectal Cancer Treatments and Studies
University of Nebraska at Omaha
2022-2025
Nebraska Medical Center
2025
University of Nebraska Medical Center
2019-2024
Duke Medical Center
2012-2018
NorthEast Regional Epilepsy Group
2016
Research Network (United States)
2016
Duke University
2010-2015
Montreal Heart Institute
2015
Université de Montréal
2015
Duke University Hospital
2012-2014
Background— The optimal treatment for ischemic mitral regurgitation remains actively debated. Our objective was to evaluate the relationship between strategy and survival. Methods Results— We retrospectively reviewed patients at our institution diagnosed with significant coronary artery disease moderate or severe from 1990 2009, categorized by medical alone, percutaneous intervention, bypass grafting (CABG), CABG plus valve repair replacement. Kaplan-Meier methods multivariable Cox...
Rectourethral fistulas are an uncommon, yet devastating occurrence after treatment for prostate cancer or trauma, and their surgical management has historically been nonstandardized. Anecdotally, irradiated rectourethral portend a worse prognosis.To review outcomes of in radiated nonirradiated patients to construct logical algorithm.A retrospective was undertaken all presenting Duke University with the diagnosis fistula from 1996 2012.Thirty-seven presented were treated fistulas: 21 received...
Rationale: The use of 6-minute-walk distance (6MWD) as an indicator exercise capacity to predict postoperative survival in lung transplantation has not previously been well studied.Objectives: To evaluate the association between 6MWD and following transplantation.Methods: Adult, first time, lung-only transplantations per United Network for Organ Sharing database from May 2005 December 2011 were analyzed. Kaplan-Meier methods Cox proportional hazards modeling used determine preoperative...
To assess trends in the frequency of concomitant vascular reconstructions (VRs) from 2000 through 2009 among patients who underwent pancreatectomy, as well to compare short-term outcomes between pancreatic resection with and without VR.Single-center series have been conducted evaluate long-term VR during resection. However, its effectiveness a population-based perspective is still unknown. Unadjusted, multivariable, propensity score-adjusted generalized linear models were...
Patients with pancreatic adenocarcinoma often present distant metastatic disease. We aimed to assess whether improvements in survival of clinical trials translated a population-based level.The US Surveillance, Epidemiology, and End Results registry was queried. Adult patients the pancreas were included from 1988 2008. Overall analyzed using Kaplan-Meier curves as well multivariable-adjusted Cox proportional hazards models.In total, 32,452 included. Mean age 67.6 (SD: 11.7) years, 15,341...
Coronary artery disease (CAD) is not uncommon among lung transplant candidates. Several small, single-center series have suggested that short-term outcomes are acceptable in selected patients who undergo coronary revascularization prior to, or concomitant with, transplantation. Our objective was to evaluate perioperative and intermediate-term this patient population at our institution. We performed a retrospective, observational cohort analysis of 898 recipients between 1997 2010. Pediatric,...
There has been increasing concern in the kidney transplant community about declining use of expanded criteria donors (ECD) despite improvement survival and quality life. The recent introduction Kidney Donor Profile Index (KDPI), which provides a more granular characterization donor quality, was expected to increase utilization marginal kidneys decrease discard rates. However, trends practice patterns ECD on national level based organ as per KDPI are not well known. We, therefore, performed...
Lung transplantation with lungs procured from donors after circulatory death (DCD) has been established as an alternative technique to traditional donation brain (DBD) comparable outcomes. Recently, in situ thoracoabdominal normothermic regional perfusion (TA-NRP) emerged a novel employed the procurement of cardiac allografts death. TA-NRP, contrast ex machine perfusion, advantage allowing assessment donor organs prior final acceptance. However, there are some concerns that this may...
Background Coronary artery disease has a high prevalence among lung transplant recipients and historically been contraindication to at many institutions. In patients with mild-to-moderate coronary (Mod-CAD) undergoing transplant, outcomes are not well defined. Methods All who underwent pulmonary transplantation from January 1996 through November 2010 pretransplant angiogram were included in our study. Recipients of multivisceral, redo, lobar transplants those revascularization excluded....
Clinical success of donation after circulatory death (DCD) heart transplantation is leading to growing adoption this technique. In comparison procurement from a brain-dead donor, DCD requires additional resources. The economic impact the hospital perspective not well known.
As donation after circulatory determination of death (DCD) heart transplantation (HT) becomes more widely adopted, there is a need to establish the most clinically effective method organ procurement. This international, multicenter study compares outcomes DCD-HT across Europe and United States (US) between recipients whose donor hearts were retrieved using thoraco-abdominal normothermic regional perfusion (taNRP) those recovered direct procurement (DPP). was retrospective observational 20...
Posterior reversible encephalopathy syndrome (PRES) is a small vessel microangiopathy of the cerebral vasculature that occurs in 0.5-5% solid organ transplant recipients, most commonly associated with tacrolimus (Tac). Clinical manifestations include hypertension and neurologic symptoms. We report an adult multivisceral recipient who experienced recurrent PRES initially Tac subsequently sirolimus. A 49-year-old woman short bowel underwent transplantation due to total parenteral...