A5039031078- Transplantation: Methods and Outcomes
- Mechanical Circulatory Support Devices
- Renal Transplantation Outcomes and Treatments
- Cardiac Structural Anomalies and Repair
- Organ Transplantation Techniques and Outcomes
- Hepatitis C virus research
- Viral Infections and Immunology Research
- Congenital Heart Disease Studies
- Cardiac Arrest and Resuscitation
- Cardiac pacing and defibrillation studies
- Heart Failure Treatment and Management
- Coronary Interventions and Diagnostics
- Optical Coherence Tomography Applications
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Liver Disease and Transplantation
- COVID-19 Clinical Research Studies
- Photoacoustic and Ultrasonic Imaging
- Pneumocystis jirovecii pneumonia detection and treatment
- Extracellular vesicles in disease
- HIV/AIDS drug development and treatment
- Fuel Cells and Related Materials
- Adenosine and Purinergic Signaling
- Cardiac Arrhythmias and Treatments
Vanderbilt University Medical Center
2015-2025
Vanderbilt Health
2014-2025
Vanderbilt University
2013-2025
Willis-Knighton Cancer Center
2024
Faculty of 1000 (United States)
2021
RELX Group (United States)
2021
International Society for Heart and Lung Transplantation
2020
American Heart Association
2017
American College of Physicians
2017
Duke Medical Center
2013
Background— High-resolution visualization of atherosclerotic plaque morphology may be essential for identifying coronary plaques that cause acute events. Optical coherence tomography (OCT) is an intravascular imaging modality capable providing cross-sectional images tissue with a resolution 10 μm. To date, OCT has not been investigated in sufficient detail to assess its accuracy characterizing plaques. The aim this study was establish objective image criteria characterization vitro. Methods...
Background— Macrophage degradation of fibrous cap matrix is an important contributor to atherosclerotic plaque instability. An imaging technology capable identifying macrophages in patients could provide valuable information for assessing vulnerability. Optical coherence tomography (OCT) a new intravascular modality that allows cross-sectional tissue with resolution ≈10 μm. The aim this study was investigate the use OCT caps. Methods and Results— images 26 lipid-rich arterial segments...
For patients awaiting heart transplant, hepatitis C-positive donors offer an opportunity to expand the donor pool, shorten wait times, and decrease wait-list mortality. While early reported outcomes among few transplant recipients have been promising, knowledge of 1-year in larger cohorts is critical shared decision-making with about this option.To better define association volumes, duration, transmission cure donor-derived C, morbidity mortality at 1 year.This was a prospective,...
Abstract Solid organ transplant (SOT) recipients are at high risk for severe coronavirus disease 2019 (COVID‐19). Studies suggest that early intervention with monoclonal antibody (MAB) treatment directed against the SARS‐CoV‐2 spike protein may reduce of emergency department visits or hospitalization COVID‐19, especially in high‐risk patients. Herein, we describe our single‐center experience 93 SOT (50 kidney, 17 liver, 11 lung, nine heart, and six dual‐organ) mild to moderate COVID‐19 who...
Background: We aimed to review the indications and outcomes of adults undergoing combined heart-liver transplantation (CHLT) in US using national registry data. Methods: Adult (≥18 years) CHLT recipients United Network for Organ Sharing database were included (09/1987-09/2020; era 1 = 1989-2000, 2 2001-2010, 3 2011-2020). Survival analysis was conducted by means Kaplan-Meier method, log-rank test, Cox regression. Results: identified 369 receiving between 12/1989-08/2020. The number adult (R2...
Background Ventricular arrhythmias are common in patients with left ventricular assist devices (LVADs) but often hemodynamically tolerated. Optimal implantable cardioverter defibrillator (ICD) tachy‐programming strategies LVAD have not been determined. We sought to determine if an ultra‐conservative ICD programming strategy affects shocks. Methods and Results Adult existing undergoing continuous flow implantation were randomized standard by their treating physician or utilizing maximal...
Treatment of adult congenital heart disease patients who require advanced therapies remains challenging due to high perioperative and wait-list mortality limited donors. Patients palliated with Fontan are at the highest risk early multiorgan involvement few centers able safely transplant them. We sought evaluate outcomes transplants in these patients.Using Nationwide Inpatient Sample database, we identified all adults aged least 18 years old underwent transplantation across U.S. hospitals...
Static cold storage with ice has been the mainstay of cardiac donor preservation. Early preclinical data suggest that allograft preservation at 10 °C may be beneficial. We tested this hypothesis by using a static device to preserve and transport allografts.
A high-resolution coronary artery imaging modality has the potential to address important diagnostic and management problems in cardiology. Optical coherence tomography (OCT) is a promising new optical technique with resolution of approximately 10 microm. The purpose this study was use OCT catheter demonstrate feasibility performing normal arteries, intimal dissections, deployed stents vivo.Normal were imaged five swine compared intravascular ultrasound (IVUS). In visualization all layers...