A5049441585- Particle physics theoretical and experimental studies
- Quantum Chromodynamics and Particle Interactions
- High-Energy Particle Collisions Research
- Health disparities and outcomes
- Insurance, Mortality, Demography, Risk Management
- Global Health Care Issues
- Genetics, Aging, and Longevity in Model Organisms
- Dementia and Cognitive Impairment Research
- Genetic Associations and Epidemiology
- Health Systems, Economic Evaluations, Quality of Life
- Health, Environment, Cognitive Aging
- Frailty in Older Adults
- Global Cancer Incidence and Screening
- Birth, Development, and Health
- Alzheimer's disease research and treatments
- Chronic Disease Management Strategies
- Nutrition and Health in Aging
- Particle Accelerators and Free-Electron Lasers
- Effects of Radiation Exposure
- Bayesian Methods and Mixture Models
- Statistical Methods and Bayesian Inference
- Statistical Methods and Inference
- Dark Matter and Cosmic Phenomena
- Nutritional Studies and Diet
- Healthcare Policy and Management
Duke University
2016-2025
Social Science Research Council
2016-2025
Belarusian State University
1997-2024
Duke Medical Center
2005-2017
Duke University Hospital
2012-2017
University Hospital of Bern
2015
University of Bern
2015
Durham VA Medical Center
2015
Thomas Jefferson National Accelerator Facility
2001-2014
Center for Child and Family Health
2007-2014
Background:Impact of contemporary treatment pre-invasive breast cancer (ductal carcinoma in situ [DCIS]) on long-term outcomes remains poorly defined. We aimed to evaluate national trends for DCIS and determine their impact disease-specific (DSS) overall survival (OS).
Results are reported from the HERMES experiment at HERA on a measurement of neutron spin structure function $g_1^n(x,Q^2)$ in deep inelastic scattering using 27.5 GeV longitudinally polarized positrons incident $^3$He internal gas target. The data cover kinematic range $0.023
Diverse pathogens (viral, bacterial, fungal) have been associated with Alzheimer's disease (AD) and related traits in various studies. This suggests that compromised immunity, rather than specific microbes, may play a role AD by increasing an individual's vulnerability to infections, which could contribute neurodegeneration. If true, then vaccines heterologous effects on extending beyond protection against the targeted disease, hold potential for prevention.
The flavor asymmetry of the light quark sea nucleon is determined in kinematic range $0.02<x<0.3$ and $1<{Q}^{2}<10{\mathrm{GeV}}^{2}$ for first time from semi-inclusive deep-inelastic scattering. quantity $[\overline{d}(x)\ensuremath{-}\overline{u}(x)]/[u(x)\ensuremath{-}d(x)]$ derived a relationship between yields positive negative pions unpolarized hydrogen deuterium targets. $\overline{d}\ensuremath{-}\overline{u}$ found to be nonzero $x$ dependent, showing an excess $\overline{d}$ over...
Objectives: time trends of age-adjusted incidence rates 19 ageing-related diseases were evaluated for 1992–2005 period with the National Long Term Care Survey and Surveillance, Epidemiology End Results Registry data both linked to Medicare (NLTCS-Medicare SEER-Medicare, respectively). Methods: calculated using individual medical histories (34,077 individuals from NLTCS-Medicare 199,418 SEER-Medicare) reconstructed information on diagnoses coded in data, dates services/procedures...
Objectives To use the Medicare Files of Service Use ( MFSU ) to evaluate patterns in incidence aging‐related diseases U.S. elderly population. Design Age‐specific rates 19 were evaluated using National Long Term Care Survey NLTCS and Surveillance, Epidemiology, End Results SEER Registry data, both linked NLTCS‐M SEER‐M , respectively), an algorithm developed for individual date at onset evaluation. Setting A random sample from entire population (Medicare beneficiaries) was used data covers...
Decline in biological resilience (ability to recover) is a key manifestation of aging that contributes increase vulnerability death with age eventually limiting longevity even people without major chronic diseases. Understanding the mechanisms this decline essential for developing efficient anti-aging and pro-longevity interventions. In paper we discuss: a) age, components contribute decline, including depletion body reserves, imperfect repair mechanisms, slowdown physiological processes...
Abstract Topics discussed at the “ Leveraging Existing Data and Analytic Methods for Health Disparities Research Related to Aging Alzheimer's Disease Dementias ” workshop, held by Duke University Association with support from National Institute on Aging, are summarized. Ways in which existing data resources paired innovative applications of both novel well‐known methodologies can be used identify effects multi‐level societal, community, individual determinants race/ethnicity, sex,...
Principal contributions to QED radiative effects in deep inelastic scattering (DIS) of polarized leptons by targets (H,D,3He) are investigated both on the Born level and taking into account corrections (RC). Scattering case transverse is also considered. All quantities presented terms covariant variables. Exact results obtained for low-order corrections. Detailed numerical analysis under conditions forthcoming polarization experiments carried out. Two points view calculation RC experimental...
OBJECTIVES: To describe the accumulation of aging‐associated health disorders using a cumulative measure known as frailty index (FI) and to evaluate its ability differentiate long‐ short‐life phenotypes well FI's connection processes in older people. DESIGN: Retrospective cross‐sectional longitudinal studies. SETTING: The National Long‐Term Care Survey (NLTCS) data that assessed functioning U.S. individuals (≥65) 1982, 1984, 1989, 1994, 1999 were analyzed. NLTCS sample each survey represents...
OBJECTIVES: To investigate the relationship between body mass index (BMI) and 9‐year mortality in older (≥65) Americans with without disability. DESIGN: Cohort study. SETTING: The unique disability‐focused National Long Term Care Survey (NLTCS) data that assessed health well‐being of individuals 1994 were analyzed. PARTICIPANTS: Four thousand seven hundred ninety‐one survey. MEASUREMENTS: BMI (kg/m 2 ) was calculated from self‐ or proxy reports height weight. analysis adjusted for 1‐year...