A5101545287- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Gastrointestinal disorders and treatments
- Head and Neck Cancer Studies
- Surgical Simulation and Training
- Hematopoietic Stem Cell Transplantation
- Abdominal vascular conditions and treatments
- Colorectal Cancer Surgical Treatments
- Lung Cancer Diagnosis and Treatment
- Gastrointestinal Bleeding Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Renal Transplantation Outcomes and Treatments
- Eosinophilic Esophagitis
- Chronic Lymphocytic Leukemia Research
- Chronic Myeloid Leukemia Treatments
- Diverticular Disease and Complications
- Diet and metabolism studies
- Pancreatic and Hepatic Oncology Research
- Biliary and Gastrointestinal Fistulas
- Potassium and Related Disorders
Toranomon Hospital
2015-2024
Hirosaki National Hospital
2019
Hirosaki University
2019
Center for Global Health
2019
National Center for Global Health and Medicine
2019
<b><i>Background:</i></b> Endoscopic submucosal resection (ESD) and endoscopic mucosal (EMR) are well established as curable safety procedures for treating superficial tumors of the stomach, esophagus colon. However, a majority strategies non-ampullary duodenal (NASDTs) remains undefined. The aim this study was to clarify which right method NASDT treatment - EMR or ESD. <b><i>Summary:</i></b> We analyzed 129 consecutive (74 ESD 55 EMR)...
Aim: Helicobacter pylori-naïve gastric cancers(GCs) have not been well documented. We aimed to characterize early H. GCs. Subjects and Methods: Of 666 patients with GC resected by endoscopic submucosal dissection, were extracted according the definition: no pylori eradication history, negative for serum pylori-antibody current pylori-infection tests, atrophy pepsinogen (PG) test, endoscopy, histology. Results: It was found that 16 GCs pylori-naïve, classified into undifferentiated...
Background and Aim Recently, the use of endoscopic submucosal dissection ( ESD ) for gastric tumor gSMT development laparoscopic cooperative surgery LECS have enabled either preservation stomach or minimization extent partial resection. In present study, outcomes following recent introduction are presented. The aim this retrospective study was to evaluate feasibility safety , including esophagogastric junction EGJ SMT . Methods is indicated lesions that an intragastric growth pattern, which...
Genetic abnormalities specific to post-H. pylori eradication gastric cancer (GC), especially those associated with undifferentiated post-eradication GC, are unknown. We conducted next-generation sequencing of GC diagnosed either before or after investigate the carcinogenesis GC. Five cases differentiated [HP(-)-D group], five H. pylori-positive [HP(+)-D four [HP(-)-U group)], and six [HP(+)-U group)] underwent analysis. DNA was extracted from tumor samples, non-tumor samples all subjects....
Introduction: Gastroesophageal reflux disease (GERD) is diagnosed based on bothersome symptoms, such as heartburn, and the presence of mucosal breaks endoscopically. Treatments that suppress gastric acid, proton pump inhibitor (PPI) vonoprazan, are frequently administered. Several studies reported regarding safety side effects long-term PPI administration, including an association with polyps. We report a case maintained symptom resolution significantly shrank polyps by performing step-down...
<b>Background and study aims:</b> In previous series, endoscopic mucosal resection (EMR) has been used for the treatment of early-stage mesopharyngeal hypopharyngeal cancers to preserve patients' quality life. Endoscopic submucosal dissection (ESD) offers potential advantages in comparison EMR. So aim this retrospective was assess utility ESD compared with EMR meso- hypopharynx. <b>Patients methods:</b> We studied 56 patients 69 lesions who underwent either or between April 2001 December...
Magnifying endoscopy with narrow band imaging (ME-NBI) is useful to diagnose invasion depth of superficial esophageal cancer. The purpose this study was evaluate the utility ME-NBI pharyngeal cancer.Between April 2008 and June 2012, 146 lesions in 104 patients who underwent en bloc resection were retrospectively analyzed. Based on magnifying endoscopic classification, proposed by Japan Esophageal Society, microvasculature type classified into B1, B2, B3.B1 alone, B3 observed 128, 14, 4...
Background/Aims . Delayed bleeding is one of the most serious complications following gastric endoscopic submucosal dissection (ESD) under antithrombotic therapy. As a safety measure, for patients receiving therapy, we covered ESD ulcer with autologous fibrin glue (prepared using blood) alone or polyglycolic acid (PGA) sheets. Methods From July 2014 to November 2015, 20 neoplasms who were therapy enrolled in this study. After ESD, ulcers PGA We prospectively evaluated feasibility measure....
Aim . To determine whether 3D endoscopic images improved recognition accuracy for superficial gastrointestinal cancer compared with 2D images. Methods We created an image catalog using and of 20 specimens resected by submucosal dissection. The twelve participants were allocated into two groups. Group 1 evaluated only at first, group 2 images, and, after interval weeks, next evaluation items as follows: (1) diagnostic the tumor extent (2) confidence levels in assessing (a) extent, (b)...
The prevalence of obesity in the Japanese population has been increasing dramatically step with Westernization lifestyles and food ways. Our study demonstrated significant associations between a number gastrointestinal disorders large sample Japan. We that reflux esophagitis hiatal hernia were strongly related to (BMI > 25) Japanese. In particular, young male was high risk for these diseases. On other hand, it reported is also associated Barrett’s esophagus colorectal adenoma; however,...
<b><i>Background/Aim:</i></b> Clinical application of 3-dimensional (3D) technology for flexible endoscopes has not been reported. We developed a 3D endoscope and conducted feasibility study endoscopic submucosal dissection (ESD) in porcine stomach. <b><i>Methods:</i></b> Four endoscopists used to perform total 8 ESD procedures on resected stomachs. assessed the en bloc resection rate, perforation mechanical issues that arise during ESD. A...
Abstract Background and study aims Many studies have shown the utility of rigid three-dimensional (3 D) endoscopes in surgery, but few reported flexible 3 D endoscopes. This ex vivo was intended to investigate whether a newly developed endoscope (GIF-Y0083; Olympus) improves diagnostic accuracy for superficial gastric tumor. Methods Twelve observers comprising experts, trainees, novices (4 each) evaluated 2 images 20 specimens resected by ESD. Evaluation items were tumor extent degree...
Objective According to consensus guidelines, eosinophilic esophagitis (EoE) is defined as a clinicopathological entity whose symptoms and histology must always be considered together. However, endoscopic findings typical of EoE are often seen in asymptomatic esophageal eosinophilia (aEE). We aimed clarify the features aEE. Methods retrospectively compared cases aEE those symptomatic EoE. Materials reviewed 146 patients who underwent upper gastrointestinal endoscopy were confirmed...
Acute graft-versus-host disease (GVHD) occurring within 100 days post-transplant is one of critical factors influencing prognosis in transplant recipients. Among cases GVHD the gastrointestinal (GI) tract, rarely affects upper GI. In this study, we retrospectively examined frequency GI and diagnostic accuracy.From among 868 patients who underwent allogeneic hematopoietic stem cell transplantation at our hospital between January 2005 June 2012, 115 whom biopsy for symptoms. The endoscopic...
Endoscopic submucosal dissection (ESD) for superficial esophageal cancer is sometimes extensive, and in our experience, patients not infrequently present with dysphagia after ESD even the absence of stricture. The aim this study was to evaluate motility using high-resolution manometry (HRM) without extensive circumferential ESD.HRM performed a total 52 who had undergone mucosal defect exceeded more than two-thirds circumference. frequency type dysmotility relationship between were...
Background and Aims . We retrospectively investigated the incidence of acute graft-versus-host disease (GVHD) in lower gastrointestinal (GI) tract diagnostic accuracy endoscopy. Methods Of 1231 patients who underwent allogeneic hematopoietic stem cell transplantation between January 2005 December 2014, 186 whom colonoscopy biopsy had no cytomegalovirus infection. The endoscopic findings histologic diagnosis from these were analyzed. Results Based on histopathological findings, 171 diagnosed...
Observation of the microvasculature using narrow band imaging (NBI) with magnifying endoscopy is useful for diagnosing superficial squamous cell carcinoma. Increased vascular density indicative cancer, but not many studies have reported differences between cancerous and noncancerous areas based on an objective comparison. We observed specimens endoscopic submucosal dissection (ESD) NBI magnification, determined areas. A total 25 lesions esophageal carcinoma that were dissected en bloc by ESD...
Objective Clipping is a common technique for managing colonic diverticular bleeding (CDB), despite the lack of published evidence regarding its effectiveness. We aimed to evaluate effectiveness clipping CDB in preventing early recurrent bleeding. Methods This dual-center retrospective study included 93 patients who underwent emergency hospitalization bloody stool, diagnosed with definitive CDB, and treated or conservative treatment. The primary outcome was A logistic regression analysis...