- Plant Molecular Biology Research
- Cancer-related gene regulation
- Chromatin Remodeling and Cancer
- Plant Gene Expression Analysis
- Wnt/β-catenin signaling in development and cancer
- Glaucoma and retinal disorders
- Sympathectomy and Hyperhidrosis Treatments
- Cancer Mechanisms and Therapy
- Plant Stress Responses and Tolerance
- Service-Oriented Architecture and Web Services
- Genomics and Chromatin Dynamics
- Plant nutrient uptake and metabolism
- Plant Reproductive Biology
- Plant responses to water stress
- Epigenetics and DNA Methylation
- Corneal surgery and disorders
- Lymphatic System and Diseases
- Genetics, Bioinformatics, and Biomedical Research
- Mechanisms of cancer metastasis
- Cognitive Computing and Networks
- Corneal Surgery and Treatments
- RNA Interference and Gene Delivery
National Institute of Biological Sciences, Beijing
2022-2024
Second Affiliated Hospital of Jilin University
2024
Nanjing University of Information Science and Technology
2023
Northwest A&F University
2022
Wnt signaling plays a critical role in development and oncogenesis. Although significant progress has been made understanding the downstream cascade of signaling, little is known regarding modification cell death machinery. Given that numerous oncogenes transform cells by providing survival function, we hypothesized may inhibit apoptosis. Here, report expressing Wnt-1 were resistant to cancer therapy–mediated inhibited cytochrome c release subsequent caspase-9 activation induced...
Abstract Although previous studies have identified several autonomous pathway components that are required for the promotion of flowering, little is known about how these cooperate. Here, we an complex (AuPC) containing both (FLD, LD and SDG26) previously unknown (EFL2, EFL4 APRF1). Loss-of-function mutations all result in increased FLC expression delayed flowering. The delayed-flowering phenotype independent photoperiod can be overcome by vernalization, confirming specifically functions...
Although the Trithorax histone methyltransferases ATX1-5 are known to regulate development and stress responses by catalyzing H3K4 methylation in Arabidopsis thaliana, it is unknown whether how these affect DNA methylation. Here, we found that redundant proteins not only required for plant viability but also regulation of The expression H3K4me3 levels both RNA-directed (RdDM) genes (NRPE1, DCL3, IDN2, IDP2) active demethylation (ROS1, DML2, DML3) were downregulated atx1/2/4/5 mutant....
Recent advancements in the field of endothelial markers lymphatic vessels and lymphangiogenic factors have shed light on association between several ocular diseases nascent vessels. The immune privilege corneal tissue typically limits formation a healthy eye. However, eyes can potentially undergo lymphangiogenesis be conditionally activated. It is evident that contribute to various pathologies. Conversely, are present limbus, ciliary body, lacrimal glands, optic nerve sheaths, extraocular...
In eukaryotes, histone acetylation levels directly regulate downstream gene expression. As a plant-specific deacetylase (HDAC), HD2D is involved in plant development and abiotic stress. However, the response of to drought stress its interacting proteins, still unclear. this study, we analysed expression patterns Arabidopsis, revealing that was highly expressed roots rosette leaves, but poorly other tissues such as stems, flowers, young siliques. The induced by d-mannitol. We investigated...
The concept of biological gene is transferred to the field command information system architecture, and architecture proposed. For networked intelligent systems, reference models are established, including resource model relationship model, 7 types operation modes 6 described abstractly. On this basis, a gene-based design process Finally, typical case used verify guiding role method in construction.