Halina Milnerowicz

ORCID: 0000-0002-0772-9852
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About
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Research Areas
  • Heavy Metal Exposure and Toxicity
  • Trace Elements in Health
  • Pancreatitis Pathology and Treatment
  • Paraoxonase enzyme and polymorphisms
  • Iron Metabolism and Disorders
  • Liver Disease Diagnosis and Treatment
  • Esophageal and GI Pathology
  • Diet, Metabolism, and Disease
  • Air Quality and Health Impacts
  • Nanoparticles: synthesis and applications
  • Pancreatic and Hepatic Oncology Research
  • Advanced biosensing and bioanalysis techniques
  • Public health and occupational medicine
  • Glutathione Transferases and Polymorphisms
  • Medical and Biological Ozone Research
  • Neuroendocrine Tumor Research Advances
  • Nanocluster Synthesis and Applications
  • Birth, Development, and Health
  • Vitamin C and Antioxidants Research
  • Cancer Research and Treatments
  • Viral gastroenteritis research and epidemiology
  • Diabetes and associated disorders
  • Esophageal Cancer Research and Treatment
  • Infant Nutrition and Health
  • Advanced Nanomaterials in Catalysis

Wroclaw Medical University
2013-2022

Mahidol University
2020

VNU University of Science
2020

Thapar Institute of Engineering & Technology
2020

Mendel University in Brno
2020

University of Veterinary Sciences Brno
2020

Veterinary Research Institute
2020

University of Wrocław
2004-2014

Wrocław University of Environmental and Life Sciences
2014

Digital Proteomics (United States)
2014

This study was aimed at evaluating the changes in concentration and activity of all superoxide dismutase isoenzymes (SOD1, SOD2, SOD3) blood patients with acute pancreatitis (AP) healthy subjects, taking into account extracellular (plasma) intracellular (erythrocyte lysate) compartment. The relationships between activity/concentration SODs, metal markers inflammation were evaluated. To assess pro/antioxidative imbalance, malonyldialdehyde (MDA) value total antioxidant capacity (TAC)...

10.3390/antiox9100948 article EN cc-by Antioxidants 2020-10-01

The aim of the study was to verify if there is any association between exposure Cu, Zn, Cd, Pb, As and formation malondialdehyde (MDA), 8-hydroxydeoxyguanosine (8-OHdG), advanced oxidation protein products (AOPP), whether in this process cigarette smoking plays a role. investigations were performed 352 smelters occupationally exposed heavy metals 73 persons control group. Metals concentration determined by atomic absorption spectrometry. MDA AOPP concentrations spectrophotometric methods....

10.1007/s12011-014-9984-9 article EN cc-by Biological Trace Element Research 2014-04-30

AgNPs have attracted considerable attention in many applications including industrial use, and their antibacterial properties been widely investigated. Due to the green synthesis process employed, nanoparticle surface can be coated with molecules biologically important characteristics. It has reported that increased use of nanoparticles elevates risk release into environment. However, little is known about behaviour eco-environment. In this study, effect synthesized on germinated plants...

10.3390/nano9111550 article EN cc-by Nanomaterials 2019-10-31

Little is known about the contribution of each three superoxide dismutase isozymes (SODs) to total SOD activity in extracellular fluids. This study was aimed investigate alterations concentration/activity plasma, context sex, obesity, exposition cigarette smoke, and genotypic variability five selected single nucleotide polymorphisms (SNPs) genes SOD1, SOD2, SOD3. Men showed higher SOD1 concentration, lower SOD3 concentration antioxidative capacity (TAC) values. Intersexual observed copper,...

10.3390/ijms21145069 article EN International Journal of Molecular Sciences 2020-07-17

Sarcosine is an amino acid that formed by methylation of glycine and present in trace amounts the body. Increased sarcosine concentrations blood plasma urine are manifested sarcosinemia some other diseases such as prostate cancer. For this purpose, detection using nanomedicine approach was proposed. In study, we have prepared superparamagnetic iron oxide nanoparticles (SPIONs) with different modified surface area. Nanoparticles (NPs) were chitosan (CS), oxidase (SOX). SPIONs without any...

10.3390/ijms19123722 article EN International Journal of Molecular Sciences 2018-11-22

Abstract The clinical use of doxorubicin (DOX) is limited by dose‐related cardiomyopathy, which becomes more prevalent with increasing cumulative doses the drug. Complexes fullerene DOX were designed and studied using biophysical methods. ability to release from at different pHs was analyzed. It has been shown that size fullerene‐DOX complexes ∼280 nm. zeta potential for ‒30 mV, ‒8 conjugates ‒24 mV. Drug CE LIF detection. When separated in a pH 7.5 buffer, 43% all signals derived free DOX,...

10.1002/elps.201800148 article EN Electrophoresis 2018-06-22

Metallothionein (MT) is a low molecular weight cysteine-rich protein with number of roles in the pro/antioxidant balance and homeostasis essential metals, such as zinc copper, detoxification heavy cadmium mercury. Until now, detection metallothionein biological fluids remained difficult because lack broadly reactive commercial test. Meaningful comparison values concentrations reported by different authors using their specific isolation procedures conditions enzyme-linked immunoassay due to...

10.18388/abp.2010_2379 article EN cc-by Acta Biochimica Polonica 2010-03-22

The aims of the present studies were to measure concentrations zinc (Zn), copper (Cu), and metallothionein Cu/Zn superoxide dismutase activity as elements engaged in an essential manner prooxidative antioxidative balance organism demonstrate degree which are involved inflammatory processes occurring pancreas.The concentration was measured by immunoenzymatic method. Serum determined using a commercial test. measurements Zn Cu serum assessed with use flame atomic absorption...

10.1097/mpa.0b013e3181a53d1 article EN Pancreas 2009-07-13

Silver nanoparticles are the most important in connection with antimicrobial effect.Nowadays, green synthesis of various types is rapid, effective and produce less toxic often specific properties.In our experiment we have developed described details silver synthesized chemically or by synthesis.Nine different were synthesized, three citrate method at pHs (8; 9; 10), four using gallic acid alkaline (10; 11), two tea coffee extracts, both pH 9. Characterisation was performed dynamic light...

10.1166/jnn.2019.15867 article EN Journal of Nanoscience and Nanotechnology 2018-12-02

The purpose of this work was to compare glutathione status in the blood women taking oral contraceptives, female smokers and pregnant using both capillary electrophoresis (CE) alloxan methods. studies were performed on whole prepared by deproteinization 25% metaphosphoric acid. reduced (GSH) measured CE Oxidized (GSSG) GSH/GSSG ratio calculated. In (Group A), contraceptives B) C), lower concentrations GSH observed compared with control group D) as methods, suggesting presence oxidative...

10.1093/chromsci/bmu035 article EN Journal of Chromatographic Science 2014-05-23

To assess the influence of smoking on level total protein, metallothionein (MT), albumin and lactoferrin in human breast milk.Samples whole milk supernatants after centrifugation at 10 000 x g 105 were analysed. Cadmium was determined by graphite furnace atomic absorption spectrometry (GFAAS). The concentration measurements employed following methods: protein Lowry, colorimetry, cotinine ELISA tests, 109Cd/haemoglobin assay.The assessment tobacco smoke exposure based concentrations (197 +/-...

10.1111/j.1651-2227.2005.tb01908.x article EN Acta Paediatrica 2005-04-01

In 114 cases of the transverse colon isolated from cadavers (50 male, 64 female), anatomical examinations arterial system were performed. Arteriograms obtained after dissecting and contrasting colonic vessels with Mixobar contrast. one case, on arteriography its mesentery a 55-year-old male cadaver, rare variant was found. The third mesenteric artery originated directly aorta-halfway between superior inferior arteries ascended obliquely in direction hepatic flexure colon. Supply area typical...

10.1007/s00276-012-0987-y article EN cc-by Surgical and Radiologic Anatomy 2012-07-21
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