- Blood Pressure and Hypertension Studies
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Coronary Interventions and Diagnostics
- Heart Failure Treatment and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Lipoproteins and Cardiovascular Health
- Cardiovascular Health and Disease Prevention
- Heart Rate Variability and Autonomic Control
- Diabetes Treatment and Management
- Cardiac Arrhythmias and Treatments
- Cardiovascular Health and Risk Factors
- COVID-19 Clinical Research Studies
- Diet and metabolism studies
- Cardiovascular Disease and Adiposity
- Venous Thromboembolism Diagnosis and Management
- Diabetes Management and Research
- Cardiac Arrest and Resuscitation
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac electrophysiology and arrhythmias
- Metabolism, Diabetes, and Cancer
- GDF15 and Related Biomarkers
Rigshospitalet
2022-2025
Gentofte Hospital
2021-2025
University of Copenhagen
2017-2025
Copenhagen University Hospital
2017-2025
Poornima University
2025
University of Toronto
2024
Yale New Haven Hospital
2019-2023
Yale University
2019-2023
Brigham and Women's Hospital
2016-2023
Zealand University Hospital
2018-2023
To examine whether the 1-h blood glucose measurement would be a more suitable screening tool for assessing risk of diabetes and its complications than 2-h measurement.We conducted prospective population-based cohort study 4,867 men, randomly selected from prespecified birth cohorts between 1921 1949, who underwent an oral tolerance test with measurements at 0, 1, 2 h. Subjects were followed up to 39 years, registry-based recording events. Discriminative abilities elevated (≥8.6 mmol/L)...
The Reference Values for Arterial Stiffness Collaboration has derived an equation using age and mean blood pressure to estimated pulse wave velocity (ePWV), which predicted cardiovascular events independently of Systematic COoronary Risk Evaluation (SCORE) Framingham Score. study aim was investigate the independent association between ePWV clinical outcomes in 107 599 apparently healthy subjects (53% men) aged 19 97 years from MORGAM Project who were included 1982 2002 38 cohorts 11...
<h3>Importance</h3> Atherosclerosis burden and coronary artery calcium (CAC) are associated with the risk for atherosclerotic cardiovascular disease (ASCVD) events, absence of plaque CAC indicating low risk. Whether this is true in patients elevated levels low-density lipoprotein cholesterol (LDL-C) not known. Specifically, a high prevalence noncalcified might signal <h3>Objective</h3> To determine calcified symptomatic adults assess its association events across LDL-C spectrum. <h3>Design,...
Abstract Objective To examine whether vitamin D supplementation in patients with depression would result a reduction Hamilton D-17 score (primary outcome) at 3 and 6 months compared to controls explore the correlations between serum symptoms of depression, wellbeing, systolic blood pressure, waist circumference. In this outpatient multicentre study conducted 2010 2013, patients, 18–65 years old, diagnosed mild severe were randomly assigned receive 70 micrograms daily or placebo on top...
Abstract This perspective covers a novel area of research describing the inadequacies current approaches for diagnosing dysglycaemia and proposes that 1‐hour post‐load glucose level during 75‐g oral tolerance test may serve as biomarker to detect earlier than currently recommended screening criteria disorders. Considerable evidence suggests plasma value ≥155 mg/dl (8.6 mmol/L) identify individuals with reduced β‐cell function prior progressing prediabetes diabetes is highly predictive those...
Abstract Multiplex proteomic platforms provide excellent tools for investigating associations between multiple proteins and disease (e.g., diabetes) with possible prognostic, diagnostic, therapeutic implications. In this study our aim was to explore novel pathophysiological pathways by examining 92 their association incident diabetes in a population-based cohort (146 cases of versus 880 controls) followed over 8 years. After adjusting traditional risk factors, we identified seven associated...
Low serum 25-hydroxyvitamin D levels (25(OH)D) have been associated with a higher likelihood of seasonal affective disorder (SAD) and poor mental well-being, yet firm evidence for either remains lacking. Thus, vitamin supplementation may alleviate symptoms SAD. This study was randomized, single-centre, double-blind, placebo-controlled trial including healthcare professionals employed in psychiatric somatic hospitals. 3345 were invited to participate, 50 participants screened, 34 able...
Aims To assess the incremental value of biomarkers, including N-terminal prohormone brain natriuretic peptide (NT-proBNP), high-sensitivity troponin T (hs-TnT), C-reactive protein (hs-CRP), interleukin-6 (IL-6), growth differentiation factor 15 (GDF-15), and procollagen type 1 propeptide (P1NP), in predicting incident cardiovascular events mortality among asymptomatic individuals from general population, beyond traditional risk factors, fasting glucose renal function (cystatin C), medication...
Abstract It is unclear whether 12‐lead ECG employing standard criteria for left ventricular hypertrophy (LVH) provides similar information with respect to long‐term cardiovascular risk as echocardiography. The authors performed a retrospective cohort study of 1376 individuals without disease, who underwent (LVH defined using the Sokolow‐Lyon voltage combination (>35 mm) or Cornell voltage‐duration product (>2440 mm × ms)) and echocardiography LV mass index (LVMI) >95 g/m 2 women...
Importance Influenza vaccination in patients with acute myocardial infarction (AMI) reduces major adverse cardiac events and is strongly recommended clinical practice guidelines. Effective strategies to improve are needed these high-risk patients. Objective To evaluate whether electronically delivered behavioral nudges influenza vaccine uptake AMI across 3 nationwide implementation randomized trials (RCTs). Design, Setting, Participants Nationwide Utilization of Danish Government Electronic...
The association between cardiovascular disease and advanced liver is incompletely understood. To explore this interaction, we compared management, clinical outcomes, readmission rates, resource utilization in ST-elevation myocardial infarction (STEMI) patients with without disease. Nationwide Readmissions Database (2016-2020) was queried to identify hospitalizations for STEMI. Cohorts were stratified by presence of Liver defined as documented diagnosis cirrhosis or failure. Multivariable...