A5057802540- Salmonella and Campylobacter epidemiology
- Vibrio bacteria research studies
- Antibiotic Resistance in Bacteria
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Viral gastroenteritis research and epidemiology
- Antibiotic Use and Resistance
- Viral Infections and Outbreaks Research
- Bacterial Identification and Susceptibility Testing
- Bacteriophages and microbial interactions
- Hepatitis B Virus Studies
- Respiratory viral infections research
- Vector-Borne Animal Diseases
- Animal Disease Management and Epidemiology
- Bacterial biofilms and quorum sensing
- SARS-CoV-2 and COVID-19 Research
- Vaccine Coverage and Hesitancy
- Antimicrobial Resistance in Staphylococcus
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Child Nutrition and Water Access
- COVID-19 epidemiological studies
- Advances in Cucurbitaceae Research
- Influenza Virus Research Studies
- Virology and Viral Diseases
Lagos State University
2016-2025
Ladoke Akintola University of Technology
2024
Creative Commons
2023
Lagos State University Teaching Hospital
2016
University of Ilorin
2016
Typhoid fever continues to pose a serious health challenge in developing countries. A reliable database on positive blood cultures is essential for prompt interventions. To generate data Salmonella enterica serovar Typhi (S. Typhi)-positive culture trends typhoidal Nigeria alongside changing contextual factors and antimicrobial resistance patterns, retrospective cohort study was conducted two hospitals Lagos between 1993 2015. Medical records of typhoid patients were reviewed antibiogram,...
Abstract Background Salmonella infections remain an important public health issue worldwide. Some serovars of non-typhoidal (NTS) have been associated with bloodstream and gastroenteritis, especially in children Sub-Saharan Africa circulating S. enterica drug resistance virulence genes. This study identified verified the clonal relationship Nigerian NTS strains isolated from humans, animals, environment. Methods In total, 2,522 samples were collected patients, animals (cattle poultry),...
Abstract Background In this priority-setting exercise, we sought to identify leading research priorities needed for strengthening future pandemic preparedness and response across countries. Methods The International Society of Global Health (ISoGH) used the Child Nutrition Research Initiative (CHNRI) method preparedness. Eighty experts in global health, translational clinical identified 163 ideas, which 42 then scored based on five pre-defined criteria. We calculated intermediate...
The COVID-19 pandemic has caused disruptions to the functioning of societies and their health systems. Prior pandemic, systems in low- middle-income countries (LMIC) were particularly stretched vulnerable. International Society Global Health (ISoGH) sought systematically identify priorities for research that would have potential reduce impact LMICs.The Child Nutrition Research Initiative (CHNRI) method was used COVID-19-related priorities. All ISoGH members invited participate. Seventy-nine...
The global spread of bla CTX-M-I extended-spectrum beta-lactamase (ESBL)-producing Salmonella spp. remains a major threat to treatment and control. Evidence emergence this marker are lacking in Nigeria. This study investigated ESBL production among isolates from hospitalized patients.Patients (158 total) made up two groups were evaluated. Group A was composed 135 patients with persistent pyrexia group B 23 gastroenteritis their stool samples. Samples cultured, identified subjected antibiotic...
Ten Nigerian medicinal plants used traditionally for the treatment of several ailments both microbial and non-microbial origins were tested on multi-drug resistant S. typhi(MDR) strains which six them active. The results revealed that aqueous ethanol extracts Terminalia avicennioides, Momordica balsamina, Combretum paniculatumand Trema guineensiswere effective MDR-S. typhistrains with minimum inhibitory concentration (MIC) bactericidal (MBC) values ranging from 9.60 to 14 mcg/ml 24 33...
<title>Abstract</title> Background Human Bocavirus (HBoV) is a single-stranded DNA virus from the Parvoviridae family that associated with respiratory and gastrointestinal infections. The prevalence impact of HBoV in Lagos, Nigeria, particularly across all age groups, remain underexplored. Aim This study aimed to determine among individuals symptoms its association disease. Methods A hospital-based, cross-sectional was conducted December 2022 May 2023 Lagos. Nasopharyngeal swabs were...
Background: Human metapneumovirus (HMPV) is an important respiratory pathogen worldwide. It a leading cause of lower infection in infants, children, elderly and immunocompromised individuals. Methods: This cross-sectional molecular epidemiological study examined HMPV among people with underlying conditions different clinics Lagos. Nasopharyngeal samples collected from 150 patients aged 1-88 years between May June, 2022 were tested by Real-Time Polymerase Chain Reaction. Samples extracted...
Abstract Background Acinetobacter baumannii , a Gram-negative bacterium, is public health threat due to its role in nosocomial infections and increasing antibiotic resistance. In Nigeria, data on the molecular epidemiology of A. scarce. This study investigates genetic diversity presence antimicrobial resistance determinants virulence-related genes whole-genome sequencing 189 Nigerian isolates deposited repositories. Genotypes were determined in-silico by multilocus sequence typing (MLST)...
The detection of Acinetobacter baumannii among patients in hospitals, particularly the Intensive Care Unit (ICU) has been a public health challenge. This study determines prevalence, virulence, and antimicrobial-resistant determinants extended-spectrum beta-lactamase (ESBL) carbapenemase-pro¬ducing A. from critically ill patients. Between April 2022 March 2023, 530 samples compris¬ing 270 Category-A (ICUs) 260 Category-B (non-ICU) attending referral hospitals Lagos were collected. analyzed...
Background: Enterococcus species present significant health risks due to their widespread presence in humans, animals, and the environment. This study examined patterns of antimicrobial resistance (AMR) carbapenemase-producing from various sources. Methods: Between November 2023 February 2024, 500 samples were collected Lagos State, including 350 clinical human samples, 50 environmental 100 animal samples. The processed, isolates identified subjected susceptibility tests (AST) by standard...
Introduction: A retrospective cohort study on Salmonella-associated diseases (SADs) was conducted in 14 public hospitals across Lagos State, Nigeria, between 1999 and 2008. Methodology: Medical records of clinically diagnosed patients with confirmed Salmonella infections were reviewed for the 10-year period. Laboratory diagnosis typhoid fever cases all first based Widal agglutination tests then followed by culture, while non-typhoidal culture technique. Results: total 85,187 SADs found,...
Salmonella spp. are important foodborne pathogens exhibiting increasing resistance to antimicrobial drugs. Resistance broad-spectrum β-lactams, mediated by extended-spectrum β-lactamase (ESBL) and AmpC enzymes is fast spreading has had negative impacts on the clinical outcomes, particularly third-generation cephalosporins. This study investigated carriage of gene among multidrug-resistant from Lagos, Nigeria.Forty samples (S. typhi = 13; S. typhimurium 10; enteritidis 8; choleraesuis 5;...
This study investigated the prevalence of Klebsiella (K.) pneumoniae isolates among clinical samples patients in four medical centers Lagos, Nigeria and burden extended-spectrum beta-lactamases (ESBL) carbapenem-resistant K. (CRKP) strains. Different (stool, blood, urine, wound swabs nasal swabs) from 127 with suspected Gram-negative infections based on on-site performed Gram-stain public hospitals between March September 2015 were analyzed. was identified 43 (34%) patients. Resistance rates...
There is scarce information about the occurrence of extended-spectrum β-lactamases (ESBLs) in Salmonella enterica serovar Typhi (S. Typhi) from patients with typhoid fever.To study antimicrobial resistance and ESBL encoding genes among S. isolates aforesaid Lagos, Nigeria.S. were collected blood samples fever 4 academic medical centers Nigeria. The identification their antibiotic susceptibility testing performed by standard bacteriological techniques disc diffusion method, respectively....
Coronavirus disease 2019 (COVID-19) pandemic has emerged as a global health crisis, with 3,855,788 infected persons and 256,862 deaths worldwide of May 9, 2020. In Nigeria, the first case was reported by Nigerian Centre for Disease Control on February 27, Between dates when index 2020, nation recorded total 4151 confirmed COVID-19 cases from 25,951 samples screened 745 (18%) discharged 128 indicating fatality rate 3.1%. Thirty-four (34) States Federal Capital Territory have coronavirus...
Introduction: Inadequate potable water supply and poor sanitation predispose to food- water-borne diseases associated with Salmonella enterica serovars in developing countries. In this study the possible source of an unprecedented upsurge Salmonella-associated community gastroenteritis was traced using both phage-typing pulsed-field gel electrophoresis (PFGE). Methodology: Nineteen Typhimurium (three sporadic isolates included) 13 Enteritidis from clinical, animal, environmental samples were...
Zika virus (ZIKV) is one of the arboviruses implicated in febrile illness, microcephaly and other neurological disorders babies whose mothers were infected during pregnancy. Information on ZIKV Nigeria limited. Hence, this study was aimed at investigating seroprevalence among pregnant women Lagos State. In a cross-sectional study, blood samples collected from 352 randomly selected four hospitals State separated plasma analyzed using IgG IgM capture Enzyme-linked immunosorbent assay...
Salmonella infections remain a global challenge. The culture method is the gold standard for detection of genus Salmonella. Application Polymerase Chain Reaction (PCR) has become an effective tool virulence and antimicrobial resistance genes. This study investigated prevalence by invA gene blaCTX-M blaCTX-M-3 markers PCR. A total 612 blood samples were collected from hospitalized febrile patients between March 2020 April 2021. cultured, isolates identified with Analytical Profile Index (API...
Abstract Arboviral infections are fast becoming a global public health concern as result of its high fatality rate and sporadic spread. From the outbreak Zika virus in Americas, endemicity Yellow fever West Africa South America, outbreaks Nile to year-round national risk Dengue Mainland China India. The war against emerging re-emerging viral infection could probably lead next pandemic. To be above pending possible arboviral pandemic, consistent surveillance these pathogens is necessary every...
Abortifacient pathogens such as bacterial [Brucella spp., Listeria Leptospira interrogans ser., Coxiella burnetii, Campylobacter Anaplasma Chlamydia spp.], mycotic [Aspergillus spp. and Candida protozoan [Toxoplasma gondii, Neospora viral [Blue tongue virus (BTV), Schmallenberg (SBV), Bovine diarrhea (BVDV), Peste des petits ruminants (PPRV)] are challenges for the productive reproductive performance of (cattle, sheep, goats) globally. No comprehensive report on epidemiology, associated risk...