A5023438798- Natural Antidiabetic Agents Studies
- Phytochemicals and Antioxidant Activities
- Retinal Diseases and Treatments
- Piperaceae Chemical and Biological Studies
- Advanced Glycation End Products research
- Essential Oils and Antimicrobial Activity
- Ginger and Zingiberaceae research
- Chronic Kidney Disease and Diabetes
- Medicinal Plants and Neuroprotection
- Neurological Disease Mechanisms and Treatments
- Biochemical Analysis and Sensing Techniques
- Neuroinflammation and Neurodegeneration Mechanisms
- Phytochemistry and Biological Activities
- Retinoids in leukemia and cellular processes
- Fungal Biology and Applications
- Problem and Project Based Learning
- Consumer Attitudes and Food Labeling
- Mangiferin and Mango Extracts
- Evaluation of Teaching Practices
- Biochemical and biochemical processes
- Diverse Scientific Research Studies
- Medicinal Plants and Bioactive Compounds
- Antioxidant Activity and Oxidative Stress
- Ginkgo biloba and Cashew Applications
- Diet and metabolism studies
University of Nottingham Malaysia Campus
2017-2025
National Institutes of Biotechnology Malaysia
2023
Mahsa University
2013
University of Malaya
2011-2013
This study aimed to evaluate the effect of four solvents (water, methanol, ethyl acetate, and n-hexane) on extraction total phenolic content (TPC), tannin, flavonoid, ferric reducing power (FRAP), radical scavenging activity from Centella asiatica, Musa acuminata, Peperomia pellucida, Psophocarpus tetragonolobus. The TPC, antioxidant varied significantly according solvent polarity plant species. strong linear correlation found between index FRAP as well indicated with increasing favored...
Abstract Solanum lycopersicum , which is commonly known as tomato, not only serves a dietary fruit vegetable but also functional food that protects humans against chronic degenerative illnesses such diabetes microvascular complications, viral diseases, and cancers. The nutritional benefit of tomato largely attributed to its phytonutrient composition. influence post‐harvest processing methods, digestion process, compounds interaction on the bio‐accessibility phytonutrients are key aspects...
Abstract Background In this priority-setting exercise, we sought to identify leading research priorities needed for strengthening future pandemic preparedness and response across countries. Methods The International Society of Global Health (ISoGH) used the Child Nutrition Research Initiative (CHNRI) method preparedness. Eighty experts in global health, translational clinical identified 163 ideas, which 42 then scored based on five pre-defined criteria. We calculated intermediate...
The present study compares water-soluble phenolic content (WPC) and antioxidant activities in Chinese long bean (Vigna unguiculata), bitter gourd (Momordica charantia), water convolvulus (Ipomoea aquatica) broccoli (Brassica olearacea) prior to after subjecting boiling, microwaving pressure cooking. total activity was increased cooked convolvulus, gourd, estimated based on the ferric reducing power, Trolox equivalent capacity 2,2-diphenyl-1-picryl-hydrazyl radical scavenging activity....
The COVID-19 pandemic has caused disruptions to the functioning of societies and their health systems. Prior pandemic, systems in low- middle-income countries (LMIC) were particularly stretched vulnerable. International Society Global Health (ISoGH) sought systematically identify priorities for research that would have potential reduce impact LMICs.The Child Nutrition Research Initiative (CHNRI) method was used COVID-19-related priorities. All ISoGH members invited participate. Seventy-nine...
This study aimed to investigate the effect of in vitro digestion on total antioxidant activity and carbohydrate hydrolyzing enzymes inhibitory potential 12 functional plant-based foods. Undigested Centella asiatica showed highest activity, phenolic flavonoid content while Morus Alba Dioscorea polystachya displayed α-glucosidase α-amylase potential, respectively. In significantly (p < 0.05) increased radical scavenging activities all plant extracts. Both (r = 0.840, p 0.001) 0.549, 0.01)...
This study aimed to compare the total phenolic (TPC), flavonoid (TFC), radical scavenging and cytotoxic activities in aqueous methanolic extracts of Angelica sinensis, Dioscorea polystachya, Ginkgo biloba, Glycyrrhiza uralensis Lycium barbarum with two dietary plants: Brassica oleracea Zingiber officinale. The TPC TFC medicinal plant were 12-93% lower than Z. officinale as follows: L. > G. A. sinensis biloba D. polystachya. decreasing activity shared similar trend: Both positively correlated...
Abstract This study investigated the effects of different heat treatments, namely boiling, microwaving and pressure cooking, on reduced ascorbic acid content antioxidant activity in Momordica charantia extracts. The total M. extracts was determined by ferric reducing-antioxidant power 2,2-diphenyl-1-picrylhydrazyl radical scavenging assays. estimated power-ascorbic assay confirmed high performance liquid chromatography. Regardless cooking method, all cooked had significantly (p < 0.05)...
Diabetic retinopathy is the most common diabetic eye disease, occurring in about 60% of type 2 patients. Other than known clinical risk factors, influence genes has been suggested as part development retinopathy. We investigated association Gly82Ser, 1704G/T and 2184A/G polymorphisms RAGE gene with patients Malaysia. Ninety-eight unrelated 185 healthy controls from all over Malaysia were recruited this study. The allele genotype frequencies three using PCR-RFLP. frequency did not differ...
Background/aims The receptor for advanced glycation end-products (RAGE) has been implicated in the pathogenesis of diabetic microvascular complications. aim this study was to investigate association between 2245G/A gene polymorphism RAGE and retinopathy Malaysian type 2 patients. Methods 342 unrelated patients (171 with (DR), 171 without (DNR)) 235 healthy subjects from all over Malaysia were recruited study. Genomic DNA isolated 3 ml samples whole blood using a modified conventional...
This study aims to investigate potential diabetic retinopathy (DR) risk factors by evaluating the circulating levels of pentosidine, soluble receptor for advanced glycation end-product (sRAGE), oxidation protein product (AOPP) as well glutathione peroxidase (GPx) and superoxide dismutase (SOD) activities in DR patients. A total 235 healthy controls, 171 type 2 without (DNR) 200 patients were recruited. Plasma was extracted estimation sRAGE, AOPP GPx activity whereas peripheral blood...