Immunotherapy faces insufficient immune activation and limited effectiveness. Herein, we report a smart DNA hydrogel that enables the release of multivalent functional units at tumor site to enhance efficacy immunotherapy. The was assembled from two types ultra-long chains synthesized via rolling circle amplification. One chain contained adjuvant CpG oligonucleotides polyaptamers for loading natural killer cell-derived exosomes; other G-quadruplex photodynamic agents. formed through...

Abstract Blueberry ( Vaccinium spp.) is a fruit recognized in the world as healthy, and many of its active ingredients have important physiological functions. This study analyzed antioxidant activity, antitumor immune function anthocyanins polyphenols extracted from blueberries. The crude extracts were obtained blueberries then purified, extract exhibited excellent dose‐dependent activity vivo vitro . purified polyphenol compounds showed higher whereas had better inhibitory effect on tumor...

A multigas detection technology based on optical-feedback cavity-enhanced Raman spectroscopy is introduced. The apparatus combines optical feedback with modulation/demodulation to realize unintermittent and precise frequency locking of a continuous-wave diode laser at 637 nm, operating moderate emitting power, high-finesse V-shaped cavity. This configuration yields stable intracavity power gain 1700 times, an reaching up 120 W. Using this apparatus, spectra multiple gases, including CO2, CO,...

Abstract Immunotherapy faces insufficient immune activation and limited effectiveness. Herein, we report a smart DNA hydrogel that enables the release of multivalent functional units at tumor site to enhance efficacy immunotherapy. The was assembled from two types ultra‐long chains synthesized via rolling circle amplification. One chain contained adjuvant CpG oligonucleotides polyaptamers for loading natural killer cell‐derived exosomes; other G‐quadruplex photodynamic agents. formed through...

In the recent years, power line communication technology has seen a rapid development. However, due to unsteadiness of channels, there are still some problems obstruction and attenuation in this field which decrease prospect scope technology. This paper is based on previous basic studies about spread spectrum OFDM (orthogonal frequency-division multiplexing) investigates methods using restrain low-voltage communications give systematic model transfer characteristic line. Meanwhile results...

Practical results are used to parameterise a physically based, compact IGBT model for three generations of (PT, NPT and IGBT3), at temperatures extending down 50 K. Full details presented the parameter variations with temperature over range 50–300 The models then examine performance sinusoidal pulse-width-modulated inverter leg cryogenic temperatures.

Agglomeration control is important for both the crystallization process and product quality optimization. Fast precise description of agglomerate crucial agglomeration control. This work proposed a synthetic image analysis method to accurately count primary particles within agglomerates by recognizing clustering salient features. In addition, new definition degree distribution was introduced underscore proportion heavy particle population. Further, were tested in raspberry...

Nanoporous copper (NPC) and nanoporous copper-nickel (NPC-Ni) can be prepared by free corrosion dealloying Mn[Formula: see text]Cu[Formula: text]Ni x ([Formula: text], 1, 3[Formula: text]at.% Ni) precursor alloys. Microscopic morphology characterization scanning electron microscopy exhibited a three-dimensional bicontinuous porous structure with nanoscale ligaments pores. NPC pore size of 48.7[Formula: text]nm was obtained in 0.1[Formula: text]M hydrochloric acid solution for 3.5[Formula:...

The impact of laser annealing on the nanocrystalline Fe–Si–B–Cu–Nb soft magnetic alloy has been investigated. experimental results showed that microstructure nanocrystals produced by is comparable to furnace annealing. However, time plays a crucial role in determining grain size and crystalline fraction evolution, thereby affecting both coercivity saturation magnetization. Nonetheless, volume annealed samples lower than ones due ultrahigh heating cooling rate, which hinders growth...

The self-assembly of artificial structures within living cells provides valuable insights into cellular mechanisms and control functions, thereby contributing to advancements in biomedicine synthetic biology. To precisely the intracellular assembly process, exogenous active substances have been introduced, which respond natural environments. Deoxyribonucleic acid (DNA) is a versatile biological macromolecule that has great potential as building block construct biomaterials addition genetic...

Abstract Tumor‐derived small extracellular vesicles (sEVs) are proven to play important roles in accelerating the progression of tumors. Destructing sEVs at tumor sites is therefore a promising route inhibit progression. Herein, smart DNA network‐based sEV trap (DNET) reported, which achieved specific capture tumor‐derived through recognizing by polyaptamers, and efficient destruction via photodynamic process sites. The DNET constructed assembly two chains generated rolling circle...

The development of low-cost and high-efficiency catalysts for wastewater treatment is great significance. Herein, nanoporous Cu/Cu2O were synthesized from MnCu, MnCuNi, MnCuAl with similar ligament size through one-step dealloying. Meanwhile, the comparisons three in performing methyl orange degradation investigated. One possessed a efficiency as high 7.67 mg·g−1·min−1. With good linear fitting by pseudo-first-order model, reaction rate constant was evaluated. In order to better understand...

First, we build a frequency hopping system model with BFSK modulation in matlab. Then, analyze the bit error rate performance FH/BFSK communication noise jamming and narrow-band jamming. Analysis showed that artificial only effects large conditions (when is above 0.1), when below 0.1, it ineffective than Finally, compare of theoretic numerical results Monte Carlo analysis, to show two scheme's are consistent some extent.

In this study, we integrate the electromagnetic soft mold imprint technique with electrophoretic deposition technique, and apply them to forming microelectrode structures. The compound casting technology is used produce a magnetic of structure, which can effectively reduce time cost molding. use an device more evenly distributed pressure, thus, structure be entirely imprinted onto indium tin oxide (ITO) substrate, then employed deposit titanium dioxide (TiO 2 ) nanopowder on ITO substrate...

Metallic core formation in differentiated bodies the inner solar system can take place between low pressures (near 1 bar) to much higher (up 100 GPa).Most thermodynamic models of metal-silicate equilibria utilise activity coefficients for metallic tracers Fe liquids, nearly all which have been carried out at pressures.This study focuses on effect pressure Au, P, V, Mn, Ga, Zn, Cd, Sn, W, Pb, and Nb liquid Fe-Si alloys.From a series experiments 10 GPa, 2373 K containing variable Si content we...

We develop a simple and competitive fabrication of antireflective (AR) films with high-ordered nanostructure arrays on polycarbonate (PC) substrate by using gas-assisted hot embossing self-assembled technique. In this method, monolayer polystyrene (PS) nanospheres is well-patterned glass substrates as the first template. Subsequently, we use plasma sputtering to deposit conductive layer onto surface nanosphere (NS) patterned substrates, then, electroforming applied fabricate nickel mold an...