Guanghui He

ORCID: 0000-0002-0912-4005
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About
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Research Areas
  • Retinal Diseases and Treatments
  • MicroRNA in disease regulation
  • Electronic Packaging and Soldering Technologies
  • Connexins and lens biology
  • Privacy-Preserving Technologies in Data
  • Corneal Surgery and Treatments
  • Extracellular vesicles in disease
  • Heme Oxygenase-1 and Carbon Monoxide
  • Advanced Fiber Optic Sensors
  • Growth Hormone and Insulin-like Growth Factors
  • Advanced MIMO Systems Optimization
  • Advanced Wireless Communication Technologies
  • Immune cells in cancer
  • Retinal Imaging and Analysis
  • Autophagy in Disease and Therapy
  • Retinal and Macular Surgery
  • Cancer-related molecular mechanisms research
  • Vascular Anomalies and Treatments
  • Lung Cancer Diagnosis and Treatment
  • Software-Defined Networks and 5G
  • Lightning and Electromagnetic Phenomena
  • Electrodeposition and Electroless Coatings
  • Flavonoids in Medical Research
  • Bone Metabolism and Diseases
  • Advanced Optical Sensing Technologies

Shanxi Medical University
2025

Second Hospital of Shanxi Medical University
2025

Shanghai University
2023-2024

Weifang People's Hospital
2021-2024

Xian Yang Central Hospital
2021-2024

Ministry of Industry and Information Technology
2022-2023

Purple Mountain Laboratories
2023

Weifang Medical University
2022

Tianjin Medical University
2016-2021

Tianjin Medical University Eye Hospital
2016-2021

Sixth-generation (6G) networks are evolving toward new features and order-of-magnitude enhancement of systematic performance metrics compared to the current 5G. In particular, 6G expected achieve extreme connectivity with Tbps-scale data rate, Kbps/Hz-scale spectral efficiency, <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$\mu\mathrm{s}$</tex> , -scale latency. To this end, an original three-layer network architecture is designed realize...

10.1109/mwc.004.2200482 article EN IEEE Wireless Communications 2023-06-01

AIM: To observe the effect of exosomes derived from human umbilical cord blood mesenchymal stem cells (hUCMSCs) on expression vascular endothelial growth factor-A (VEGF-A) in blue light injured retinal pigment epithelial (RPE) and laser-induced choroidal neovascularization (CNV) rats. METHODS: Exosomes were isolated hUCMSCs characterized by transmission electron microscope Western blot. MSCs-derived cultured with RPE exposed to light. The mRNA protein VEGF-A determined real time-polymerase...

10.18240/ijo.2018.04.04 article EN cc-by-nc-nd International Journal of Ophthalmology 2018-04-11

Purpose: Age-related macular degeneration (AMD) is a major cause of blindness in the elderly, and activation NACHT, LRR, PYD domain-containing protein 3 (NLRP3) inflammasome involved AMD pathogenesis. We investigated whether photooxidative blue-light stimulation retinal pigment epithelium (RPE) cells promotes exosome secretion modulates activity NLRP3 vitro.Methods: Exosomes were isolated from ARPE-19 cultures stimulated or not with photostimulation (488 nm). Isolated exosomes characterized...

10.1080/02713683.2018.1518458 article EN Current Eye Research 2018-09-10

In this study, we evaluated the effects of intermittent high glucose on oxidative stress production in retinal pigmented epithelial (RPE) cells and explored whether mechanisms autophagy apoptosis are associated with high-mobility group box 1 (HMGB1) protein.Cultured human RPE cell line ARPE-19 were exposed to glucose-induced stress. Reactive oxygen species (ROS) was determined by 2', 7'-dichlorofluorescin diacetate (DCFH-DA); malonyldialdehyde (MDA), superoxide dismutase (SOD) commercial...

10.1186/s12886-018-0864-5 article EN cc-by BMC Ophthalmology 2018-08-06

To evaluate the role of cone-beam computed tomography (CT) performed for determination artery Adamkiewicz (AKA) suspected by angiography during trans-catheter bronchial embolization hemoptysis. METHODSIn this retrospective study, 17 patients with hemoptysis who underwent CT evaluation AKA prior to arterial from December 2014 March 2022 were included.During angiographic session, two interventional radiologists selected possible AKAs that defined as obscured hairpin-curved vessels arising...

10.4274/dir.2022.221646 article EN cc-by-nc Diagnostic and Interventional Radiology 2023-01-13

Abstract Electroplated micropore interconnection is one of the core technologies to realize electronic connections high-density multilayer Printed circuit board (PCB). The quality electroplated copper layer a key factor for reliability PCB and components. Focusing on acid plating process, this paper expounds development electroplating solution additives, mechanisms deposition hole filling mechanism, process control electroplating, which will provide reference in-depth study technology.

10.1088/1742-6596/2430/1/012011 article EN Journal of Physics Conference Series 2023-02-01

To investigate the effect of overexpression C-X-C chemokine receptor type 4 (CXCR4) on homing mesenchymal stem cells (MSCs) in vitro and therapeutic effects diabetic retinopathy (DR) vivo.MSCs were infected by lentivirus constructed with CXCR4. The expression CXCR4 was examined immunofluorescence, Western blot, quantitative polymerase chain reaction. CXCR4-overexpressing MSCs cultured to evaluate their chemotaxis, migration, apoptotic activities. intravitreally injected observe compare a...

10.18240/ijo.2018.05.08 article EN cc-by-nc-nd International Journal of Ophthalmology 2018-05-14

Remote heart rate (HR) estimation via facial videos has emerged as an attractive application for healthcare monitoring. Long short-term memory (LSTM) is a kind of deep recurrent neural network architecture used modeling sequential information, which can be utilized remote HR estimation. Outsourcing computation emerging paradigm enterprises or individuals with huge volume private data but limited computing power and analysis, the risks privacy leakage cannot ignored. Prior privacy-preserving...

10.1109/jiot.2023.3290651 article EN IEEE Internet of Things Journal 2023-06-29

Abstract Background To analyze the efficacy of stereotactic ablative brachytherapy (SABT) and percutaneous microwave ablation (MWA) for treatment early-stage non-small cell lung cancer (NSCLC). Methods Patients with (T1-T2aN0M0) NSCLC who underwent CT-guided SABT or MWA between October 2014 March 2017 at four medical centers were retrospectively analyzed. Survival, response, procedure-related complications assessed. Results A total 83 patients included in this study. The median follow-up...

10.1186/s12885-024-12055-6 article EN cc-by BMC Cancer 2024-03-06

Abstract Background In our previous study, we indicated that scutellarin (SCU) induced an anticancer effect in A549 cells. However, whether SCU regulates the radiosensitivity of non‐small cell lung cancer (NSCLC) and its related mechanism is still unclear. Methods this explored by iodine‐125 ( 125 I) at a sensitizing concentration H1975 Cellular apoptosis proliferation were detected flow cytometry, Bcl‐2/Bax expression level, cycle, CCK‐8, EdU staining. A tumor model using nude mice was also...

10.1111/1759-7714.14077 article EN Thoracic Cancer 2021-07-13

Abstract Iodine-125 (I-125) radioactive seed implantation is used for the local treatment of hepatocellular carcinoma (HCC), but molecular mechanisms regulating its anticancer effects remain incompletely understood. In this study, we report that hsa_circ_0000647 (circSEC11A) highly expressed after I-125 in HCC cell lines and tissues a key regulator I-125-induced effects. CircSEC11A acts as competing endogenous RNA (ceRNA) to sponge miR-3529-3p, promoting expression zinc fingers homeoboxes 2...

10.1038/s41420-023-01593-w article EN cc-by Cell Death Discovery 2023-08-10

To investigate the protective effect of human umbilical cord mesenchymal stem cells (hUCMSCs) modified by LIF gene on retinal function diabetic model rats and preliminarily explore possible mechanism.A stably transfected cell line hUCMSCs overexpressing leukemia inhibitory factor (LIF) was constructed. Overexpression verified fluorescent quantitative polymerase chain reaction (qPCR). Forty-eight adult Sprague-Dawley were randomly divided into a normal control group (group A),...

10.18240/ijo.2021.10.06 article EN cc-by-nc-nd International Journal of Ophthalmology 2021-09-24

The purpose of this study was to compare imaging features between COVID-19 and mycoplasma pneumonia (MP).The data patients with mild MP who underwent chest computed tomography (CT) examination from February 1, 2020 April 17, were retrospectively analyzed. Pneumonia-CT-LKM-PP model based on a deep learning algorithm used automatically quantify the number, volume, involved lobes pulmonary lesions, longitudinal changes in quantitative parameters assessed three CT follow-ups.A total 10 13...

10.1186/s12880-022-00750-4 article EN cc-by BMC Medical Imaging 2022-02-06

Outsourced inference services have greatly promoted the popularization of deep learning, and neural network models can help users customize a series personalized applications, e.g., face recognition, image classification, etc. However, untrustworthy service providers also bring variety security issues, such as data privacy, model Meanwhile, malicious example will result in output incorrectly. For above concerns, this paper proposes privacy-reserving against adversarial attack (PPNNI) under...

10.1109/tsc.2024.3399648 article EN IEEE Transactions on Services Computing 2024-01-01

The incidence of lung cancer is the highest among all tumors, and treatment has become an urgent problem to be solved. Drug-eluting bead-based bronchial arterial chemoembolization (DEB-BACE) combination immunotherapy a rare neoadjuvant therapy for surgery, which can significantly reduce time it takes patients undergo surgery.We report male patient, aged 59-year-old, with Stage-III b squamous cell accompanied by hemoptysis underwent surgical resection after DEB-BACE 21 days later without...

10.2147/imcrj.s491862 article EN cc-by-nc International Medical Case Reports Journal 2024-12-01

Sixth-generation (6G) networks are evolving towards new features and order-of-magnitude enhancement of systematic performance metrics compared to the current 5G. In particular, 6G expected achieve extreme connectivity with Tbps-scale data rate, Kbps/Hz-scale spectral efficiency, $\mu$s-scale latency. To this end, an original three-layer network architecture is designed realise uniform full-spectrum cell-free radio access provide task-centric agile proximate support for diverse applications....

10.48550/arxiv.2208.01190 preprint EN cc-by-nc-sa arXiv (Cornell University) 2022-01-01

Objective To observe the outcome of scleral buckle and vitrectomy for familial exudative vitreoretinopathy (FEVR) associated rhegmatogenous retinal detachment (RRD) with different stages. Methods Twenty eyes in 19 patients were included this study. All staged according to staging system FEVR. There are 7 at stage 3A, 4 4A, 6 4B, 3 5. According classification (RD) proliferative (PVR), PVR B was 5 eyes, C1 2 C2 C3 D1 3eyes. Retinal holes responsible RD could be found every case. Scleral...

10.3760/cma.j.issn.1005-1015.2016.05.012 article EN Zhonghua yandibing zazhi 2016-09-25

Objective To observe the effect of exosomes derived from human umbilical cord blood mesenchymal stem cells (hUCMSC) on expression vascular endothelial growth factor (VEGF) A in blue light injured retinal pigment epithelial (RPE) cells. Methods hUCMSC were cultured with exo-free fetal bovine serum for 48 hours, and then supernatants collected to isolate purify by gradient ultracentrifugation method. Transmission electron microscopy was used identify morphology exosomes. Surface...

10.3760/cma.j.issn.1005-1015.2016.06.010 article EN Zhonghua yandibing zazhi 2016-11-25
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