A5100750718- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Medical Imaging and Pathology Studies
- Advanced Radiotherapy Techniques
- Image and Signal Denoising Methods
- Aortic aneurysm repair treatments
- Advanced Image Processing Techniques
- Image Processing Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- interferon and immune responses
- Healthcare and Venom Research
- Aortic Disease and Treatment Approaches
- Medical Imaging Techniques and Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer, Hypoxia, and Metabolism
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cancer Genomics and Diagnostics
- Vascular Anomalies and Treatments
- Optical Coherence Tomography Applications
- Liver Disease Diagnosis and Treatment
- MicroRNA in disease regulation
- Lung Cancer Research Studies
- Advanced Neuroimaging Techniques and Applications
- Infectious Aortic and Vascular Conditions
- Abdominal vascular conditions and treatments
Shandong University
2004-2024
Second Hospital of Shandong University
2014-2024
Harbin Institute of Technology
2024
Southern Medical University
2024
Zhujiang Hospital
2024
Shandong First Medical University
2023
Shandong Provincial Hospital
2023
Chinese Academy of Sciences
2022
Institute of Chemistry
2022
Johns Hopkins University
2019-2021
BackgroundCurrent lung cancer screening guidelines use either mean diameter, volume, or density of the largest nodule on previous CT scan appearance a new to ascertain timing next scan. We aimed develop an accurate protocol by estimating 3-year risk after two scans using deep learning radiologists' readings and other universally available clinical information.MethodsA algorithm (referred as DeepLR) was developed data from participants who had received at least up 2 years apart in National...
Microwave ablation (MWA) is an effective and safe approach for the treatment of ground-glass nodule (GGN)-like lung cancer, but long-term follow-up warranted. Therefore, this multi-center retrospective study aimed to evaluate results MWA peripheral GGN-like cancer with a follow-up.From June 2013 January 2018, total 87 patients (47 males 40 females, mean age 64.6 ± 10.2 years) lesions showing GGN (mean long axis diameter, 17 5 mm) underwent computed tomography (CT)-guided percutaneous MWA....
The purpose of the study is to retrospectively evaluate safety and efficacy microwave ablation (MWA) for treatment ground-glass opacity (GGO)-lung adenocarcinoma.From December 2013 June 2017, a total 51 patients (22 males 29 females, mean age 69.4 ± 10.1 years) were included in this study, with lung adenocarcinoma lesions showing GGO (mean long-axis diameter 18.7 6.05 mm). They received 52 sessions percutaneous computed tomography-guided (CT-guided) MWA. First, was histologically defined by...
Curcumin can inhibit proliferation of liver cancer cells by inducing apoptosis, but the specific signaling pathways involved are not completely clear. Here, we report that curcumin inhibited MHCC97H induction apoptosis in a concentration dependent manner via stimulating intracellular reactive oxygen species (ROS) generation. Also, showed increased ROS formation activated TLR-4/MyD-88 pathway, resulting activation caspase-8 and caspase-3, which eventually led to cells. These results as an...
Background The study was conducted to investigate the effectiveness and cost of computed tomography (CT)‐guided percutaneous microwave ablation (MWA) thoracoscopic lobectomy for stage I non‐small cell lung cancer (NSCLC). Methods We retrospectively analyzed data 46 85 patients with NSCLC treated CT‐guided MWA or lobectomy, respectively, at our center from July 2013 June 2015. Overall survival (OS), disease‐free (DFS), local control rate, hospital stay, were evaluated. Survival curves...
Background Scutellarin (SCU), a flavonoid isolated from Erigeron breviscapus (Vant.) Hand.‐Mazz., increases autophagy and apoptosis in the adenocarcinoma A549 cell line, which is resistant to cisplatin. However, whether SCU alone has antitumor activity against non‐small lung cancer (NSCLC) unknown. Methods Cell Counting Kit‐8, flow cytometry, colony formation, Hoechst 33258 staining, Western blot analyses were used examine proliferation of cells treated with possible molecular mechanisms....
To evaluate the efficacy and safety of combination computed tomography (CT)-guided iodine-125 brachytherapy bronchial arterial chemoembolization (BACE) for locally advanced stage III non-small cell lung cancer (NSCLC) after failure concurrent chemoradiotherapy.We retrospectively evaluated 28 patients with NSCLC in whom chemoradiotherapy had failed were consequently, treated radioactive seed implantation followed by BACE. The prescribed radiation dose was 140 Gy, a median radioactivity 0.60...
Surgery remains the first choice of cure for early stage lung cancer. However, many patients are diagnosed at advanced stage, and thus miss opportunity to undergo surgery. As such derive limited benefits from chemotherapy or radiotherapy, alternatives focusing on local control have emerged, including iodine‐125 seed implantation. The Interstitial Brachytherapy Society, Committee Minimally Invasive Therapy in Oncology, Chinese Anti‐Cancer Association organized a group multidisciplinary...
The association of TGF beta1 polymorphisms and atrial fibrillation (AF) in essential hypertensive (EH) subjects remains unknown. Methods EH with AF (EH+AF+) sinus rhythm (EH+AF-) were enrolled. +869 T --> C at codon 10 + 915 G 25, genotyped. clinical characteristics including serum levels detected.The GG genotypes +915 25 more prevalent from EH+AF+ group than those EH+AF- (P = 0.009). genotype had the highest mean level, which was significantly higher that (3.18 +/- 0.24 ng/dl vs.2.29 0.14...
Abstract Background To analyze the efficacy of stereotactic ablative brachytherapy (SABT) and percutaneous microwave ablation (MWA) for treatment early-stage non-small cell lung cancer (NSCLC). Methods Patients with (T1-T2aN0M0) NSCLC who underwent CT-guided SABT or MWA between October 2014 March 2017 at four medical centers were retrospectively analyzed. Survival, response, procedure-related complications assessed. Results A total 83 patients included in this study. The median follow-up...
BackgroundShugan Lidan Xiaoshi granules (SLXG) is a herbal granule formulation developed by extensively modifying multiple traditional Chinese medicine compound prescriptions known for their ability to dissolve stones. It primarily used the prevention and treatment of cholelithiasis possesses significant therapeutic potential in both preventing treating acute pancreatitis. However, preventive effects SLXG on cholelithiasis-related complications, such as pancreatitis (AP), have been...
Abstract Background While minimizing plan delivery time is beneficial for proton therapy in terms of motion management, patient comfort, and treatment throughput, it often poses a tradeoff with optimizing quality. A key component the energy switching time, which approximately proportional to number layers, that is, cardinality. Purpose This work aims develop novel optimization method can efficiently compute pareto surface between quality layer cardinality, planner navigate through this...