Daria Manos

ORCID: 0000-0003-3942-1323
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About
Contact & Profiles
Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Lung Cancer Treatments and Mutations
  • Radiology practices and education
  • Radiation Dose and Imaging
  • Tracheal and airway disorders
  • Medical Imaging Techniques and Applications
  • Ultrasound in Clinical Applications
  • Medical Imaging and Pathology Studies
  • Global Cancer Incidence and Screening
  • Venous Thromboembolism Diagnosis and Management
  • Diversity and Career in Medicine
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Advanced X-ray and CT Imaging
  • Salivary Gland Tumors Diagnosis and Treatment
  • Vascular Anomalies and Treatments
  • Pulmonary Hypertension Research and Treatments
  • Lymphoma Diagnosis and Treatment
  • Delphi Technique in Research
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Esophageal Cancer Research and Treatment
  • Colorectal Cancer Screening and Detection
  • Pleural and Pulmonary Diseases
  • COVID-19 diagnosis using AI
  • Pneumothorax, Barotrauma, Emphysema

Dalhousie University
2016-2025

University of Ioannina
2025

Nova Scotia Health Authority
2017-2024

Victoria General Hospital
2023

Health Sciences Centre
2023

Queen Elizabeth II Health Sciences Centre
2014-2020

Victoria General Hospital
2020

Université de Sherbrooke
2018

Vancouver General Hospital
2007-2008

University of British Columbia
2007

Major issues in the implementation of screening for lung cancer by means low-dose computed tomography (CT) are definition a positive result and management nodules detected on scans. We conducted population-based prospective study to determine factors predicting probability that first CT scans malignant or will be found follow-up.We analyzed data from two cohorts participants undergoing screening. The development set included Pan-Canadian Early Detection Lung Cancer Study (PanCan). validation...

10.1056/nejmoa1214726 article EN New England Journal of Medicine 2013-09-04

IntroductionLung cancer risk prediction models have the potential to make programs more affordable; however, economic evidence is limited.MethodsParticipants in National Lung Cancer Screening Trial (NLST) were retrospectively identified with tool developed from Prostate, Lung, Colorectal and Ovarian Trial. The high-risk subgroup was assessed for lung incidence demographic characteristics compared those low-risk Pan-Canadian Early Detection of Study (PanCan), which an observational study that...

10.1016/j.jtho.2017.04.021 article EN cc-by-nc-nd Journal of Thoracic Oncology 2017-05-10

BackgroundCurrent lung cancer screening guidelines use either mean diameter, volume, or density of the largest nodule on previous CT scan appearance a new to ascertain timing next scan. We aimed develop an accurate protocol by estimating 3-year risk after two scans using deep learning radiologists' readings and other universally available clinical information.MethodsA algorithm (referred as DeepLR) was developed data from participants who had received at least up 2 years apart in National...

10.1016/s2589-7500(19)30159-1 article EN cc-by The Lancet Digital Health 2019-10-17

On March 11, 2020, the World Health Organization declared infection related to a novel coronavirus (SARS-CoV-2) pandemic. The role and impact of imaging predates this declaration continues change rapidly. This article is consensus statement provided by Canadian Society Thoracic Radiology Association Radiologists outlining in COVID-19 patients. objectives are answer key questions chest provide guidance for radiologists who interpreting such studies during radiography (CXR), computed...

10.1177/0846537120924606 article EN cc-by Canadian Association of Radiologists Journal 2020-05-08

It is estimated that millions of North Americans would qualify for lung cancer screening and billions dollars national health expenditures be required to support population-based computed tomography programs. The decision implement such programs should informed by data on resource utilization costs.Resource were collected prospectively from 2059 participants in the Pan-Canadian Early Detection Lung Cancer Study using low-dose (LDCT). Participants who had 2% or greater risk over 3 years a...

10.1097/jto.0000000000000283 article EN cc-by-nc-nd Journal of Thoracic Oncology 2014-08-08

The purpose of this study is to establish provincial diagnostic reference levels (DRLs) and determine whether process may help reduce the patient radiation dose from most frequently performed CT examinations.We investigated following examinations: head, chest, low-dose abdomen pelvis, abdomen, pelvis examinations. sample for each protocol included 15 patients average body weight (mean [± SD], 70 ± 20 kg). differences in between scanners were evaluated using one-way ANOVA. Correlations dose,...

10.2214/ajr.16.16361 article EN American Journal of Roentgenology 2017-03-01

Plasma pro-surfactant protein B (pro-SFTPB) levels have recently been shown to predict the development of lung cancer in current and ex-smokers, but ability pro-SFTPB measures chronic obstructive pulmonary disease (COPD) severity is unknown. We evaluated performance characteristics as a biomarker function decline population ex-smokers. were measured 2503 ex-smokers enrolled Pan-Canadian Early Detection Lung Cancer Study. Linear regression was performed determine relationship changes forced...

10.1183/09031936.00184214 article EN European Respiratory Journal 2015-01-22

Background and Objective: Incidental pulmonary nodules (IPNs) are common increasingly detected with the overall rise of radiologic imaging. Effective IPN management is necessary to ensure lung cancer not missed. This study aims describe current landscape in Canada, understand barriers optimal management, identify opportunities for improvement. Methods: We performed a narrative literature review by searching biomedical electronic databases relevant articles published between January 1, 2010,...

10.21037/jtd-23-1453 article EN Journal of Thoracic Disease 2024-02-01

We evaluated the reliability of various multidetector computed tomography (MDCT) parameters for diagnosis and severity assessment pulmonary hypertension (PH) with consideration World Health Organization (WHO) classification.A total 172 patients were included in this retrospective study. One hundred fourteen had a PH (mean artery pressure ≥25 mm Hg), 58 without <20 Hg) served as control subjects. The grouped according to WHO classification based on etiology.The significantly greater main,...

10.1097/rct.0b013e31824afbdf article EN Journal of Computer Assisted Tomography 2012-01-01

There is a need to expand eligibility criteria for lung cancer screening beyond age and smoking history. In this study, we sought assess whether light-or-never-smokers heavy smokers differ in molecular immunologic markers based on conventional criteria.

10.1503/cjs.015223 article EN Canadian Journal of Surgery 2025-01-03

Abstract RATIONALE: Appropriate management of low-dose computed tomography (LDCT) screening detected lung nodules will have significant implications for health care resource utilization and minimizing harm from radiation exposure related to imaging studies, invasive procedures clinically distress. OBJECTIVES We aimed to: provide a practical, evidence-based best practice framework healthcare professionals (HP) manage LDCT identify areas that require future studies. METHODS The Canadian...

10.1080/24745332.2020.1819175 article EN Canadian Journal of Respiratory Critical Care and Sleep Medicine 2020-10-01

The investigation of acute pulmonary embolism is a common task for radiologists in Canada. Technical image quality and reporting must be excellent; life-threatening disease that should not missed but overdiagnosis unnecessary treatment avoided. most frequently performed imaging investigation, computed tomography angiogram (CTPA), can limited by poor arterial opacification, technical artifacts interpretative errors. Image affected patient factors (such as body habitus, motion artifact cardiac...

10.1177/08465371211000739 article EN Canadian Association of Radiologists Journal 2021-03-29

Acute pulmonary embolism (APE) is a well-recognized cause of circulatory system compromise and even demise which can frequently present diagnostic challenge for the physician. The primarily due to frequency indeterminate presentations as well several other conditions have similar clinical presentation. This often obliges physician establish firm diagnosis potentially serious outcomes related this disease. Computed tomography angiography (CTPA) has increasingly cemented its role primary...

10.1177/08465371211000737 article EN Canadian Association of Radiologists Journal 2021-03-29

Guidelines aimed at improving care for lung cancer, the leading cause of cancer-related death in Canada and worldwide, require accurate knowledge diagnostic setting or pathway. We sought to determine how often cancer is initially diagnosed through emergency department.We performed a descriptive study that included all cases primary residents Nova Scotia 2014. Cancer registry data date Aug. 31, 2016. reviewed linked hospital records, including laboratory imaging results, identify first...

10.9778/cmajo.20180061 article EN CMAJ Open 2019-01-01
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