A5021611399- Treatment of Major Depression
- Acute Ischemic Stroke Management
- Atrial Fibrillation Management and Outcomes
- Cardiac Health and Mental Health
- Antiplatelet Therapy and Cardiovascular Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Cerebrovascular and Carotid Artery Diseases
- Stroke Rehabilitation and Recovery
- Clinical practice guidelines implementation
- Cardiac, Anesthesia and Surgical Outcomes
- Venous Thromboembolism Diagnosis and Management
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Lung Cancer Diagnosis and Treatment
- Pharmaceutical studies and practices
- Pleural and Pulmonary Diseases
- Urinary Tract Infections Management
- Urological Disorders and Treatments
- Electroconvulsive Therapy Studies
- Pharmaceutical Economics and Policy
- Radiology practices and education
- Schizophrenia research and treatment
- Delphi Technique in Research
- Mental Health Research Topics
- Lung Cancer Treatments and Mutations
- Pain Mechanisms and Treatments
University of Toronto
2016-2025
McGill University
2020-2025
University of Ottawa
2020-2025
Université de Montréal
2020-2025
Hôpital du Sacré-Cœur de Montréal
2025
University of Alberta
2025
Jewish General Hospital
2025
Memorial University of Newfoundland
2025
Cambridge University Press
2023
University of Calgary
2020-2023
The 2017 update of Canadian Stroke Best Practice Recommendations for the Secondary Prevention is a collection current evidence-based recommendations intended use by clinicians across wide range settings. goal to provide guidance prevention ischemic stroke recurrence through identification and management modifiable vascular risk factors. include those related diagnostic testing, diet lifestyle, smoking, hypertension, hyperlipidemia, diabetes, antiplatelet anticoagulant therapies, carotid...
Background The Canadian Network for Mood and Anxiety Treatments (CANMAT) last published clinical guidelines the management of major depressive disorder (MDD) in 2016. Owing to advances field, an update was needed incorporate new evidence provide revised recommendations assessment MDD adults. Methods CANMAT convened a editorial group comprised academic clinicians patient partners. A systematic literature review conducted, focusing on reviews meta-analyses since 2016 guidelines....
This article presents the case that a more rapid, individualized approach to treating major depressive disorder (MDD) may increase likelihood of achieving full symptomatic and functional recovery for individual patients studies show it is possible make earlier decisions about appropriateness treatment in order rapidly optimize treatment.A PubMed search was conducted using terms including disorder, early improvement, predictor, duration untreated illness, function. English-language articles...
KEY POINTS The goal of the Canadian Cardiovascular Harmonized National Guideline Endeavour (C-CHANGE) process is to give all health care providers easy access a comprehensive and practical set harmonized guideline recommendations. Clinicians claim that there are too many guidelines
Background and Objective: Incidental pulmonary nodules (IPNs) are common increasingly detected with the overall rise of radiologic imaging. Effective IPN management is necessary to ensure lung cancer not missed. This study aims describe current landscape in Canada, understand barriers optimal management, identify opportunities for improvement. Methods: We performed a narrative literature review by searching biomedical electronic databases relevant articles published between January 1, 2010,...
Canada has historically been among the world leaders in hypertension care, but treatment and control rates have regressed recent years. This guideline is intended to provide pragmatic primary care-focused recommendations improve management adults at population level. We employed Grading of Recommendations Assessment, Development Evaluation ADAPTE frameworks accordance with Appraisal Guidelines for Research (AGREE II) quality reporting standards develop on managing aged 18 years older. used...
Background: Canada has historically been among the world leaders in hypertension care, but treatment and control rates have regressed recent years. This guideline is intended to provide pragmatic primary care-focused recommendations improve management adults at population level. Methods: We employed Grading of Recommendations Assessment, Development Evaluation ADAPTE frameworks accordance with Appraisal Guidelines for Research (AGREE II) quality reporting standards develop on managing aged...
Objectives To characterize the effects of adjunctive brexpiprazole on patient life engagement and depressive symptoms in patients with major disorder (MDD) using patient-reported outcomes. Methods An 8-week, Phase 4, open-label, interventional study was conducted at 15 Canadian trial sites between April 2021 May 2022. Adult outpatients MDD (at least moderately severe) inadequate response to 1–2 antidepressants continued their current antidepressant received oral 0.5–2 mg/day. Co-primary...
KEY POINTS In 2016, 270 204 people in Canada (excluding Quebec) were admitted to hospital for heart conditions, stroke and vascular cognitive impairment, including 107 391 women 162 813 men, of whom 91 524 died.[1][1] This equates 1 out every 3 deaths outpaces other diseases
Introduction: Incidental pulmonary nodules (IPN) are common radiologic findings, yet management of IPNs is inconsistent across Canada. This study aims to improve IPN based on multidisciplinary expert consensus and provides recommendations overcome patient system-level barriers. Methods: A modified Delphi technique was conducted. Multidisciplinary experts with extensive experience in lung nodule Canada were recruited participate the panel. survey administered 3 rounds, using a 5-point Likert...
To estimate the rate of non-vitamin K oral anticoagulant (NOAC) dosing that is lower- and higher-than-recommended to describe reasons for NOAC dose discordance with Health Canada prescribing information.The OPTIMAL AF Programme was an observational cohort quality assessment initiative in which primary specialty care physicians eight provinces provided a snapshot their anticoagulated non-valvular atrial fibrillation (NVAF) patients through either electronic medical record (EMR) system or...
Switches between branded (reference) medications and the corresponding generic or two different occur commonly during treatment of central nervous system disorders. Prescribing a product in place reference can reduce patient pharmacy costs. But there be implications. Planned unplanned switches from one to another ongoing may introduce variability drug exposure which could turn compromise efficacy and/or tolerability. Studies comparing initiation versus products do not provide clear evidence...
[Voir la version anglaise de l'article ici: www.cmaj.ca/lookup/doi/10.1503/cmaj.220138][1] Points clés L'objectif du projet C-CHANGE (Canadian Cardiovascular Harmonized National Guideline Endeavour), une initiative d'harmonisation des lignes directrices nationales prévention et
Optimal thromboprophylaxis in atrial fibrillation (AF) requires the accurate application of modern clinical guidelines. We evaluated point prevalence and factors associated with nonguideline-directed anticoagulation direct oral anticoagulant (DOAC) dosing Canadian patients AF. TRANSECT-AF is a retrospective registry consecutive AF collected between March 2021 August 2023. Patients were categorized as guideline directed therapy (GDT) or (NGDT) based on concordance their reported CHADS-65...
POINTS CLÉS En 2016, au Canada (à l’exclusion du Québec), 270 204 personnes ont été admises à l’hôpital pour un trouble cardiaque, accident vasculaire cérébral (AVC) ou déficit cognitif d’origine vasculaire; de ce nombre, 107 391 étaient des femmes, 162 813 hommes
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