A5043813168- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Heart Failure Treatment and Management
- Transplantation: Methods and Outcomes
- Ethics in Clinical Research
- Cardiac pacing and defibrillation studies
- Ethics in medical practice
- Biomedical Ethics and Regulation
- Renal Transplantation Outcomes and Treatments
- Cardiac Arrest and Resuscitation
- Cardiac Health and Mental Health
- Cardiac Arrhythmias and Treatments
- Astronomy and Astrophysical Research
- Cardiovascular Function and Risk Factors
- Galaxies: Formation, Evolution, Phenomena
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Organ Transplantation Techniques and Outcomes
- Medication Adherence and Compliance
- Viral Infections and Immunology Research
- Telemedicine and Telehealth Implementation
- Cardiovascular and exercise physiology
- Congenital Heart Disease Studies
- Electoral Systems and Political Participation
- Chronic Disease Management Strategies
University Health Network
2016-2025
Massachusetts Institute of Technology
2022-2025
Johannesburg Hospital
2025
University of Toronto
2015-2024
Ted Rogers Centre for Heart Research
2016-2024
Vassar College
2024
University of British Columbia
2007-2023
Fairfield University
2023
Toronto General Hospital
2011-2023
Toronto Public Health
2011-2023
Data regarding coronavirus disease 2019 (COVID-19) outcomes in solid organ transplant recipients (SOTr) across severe acute respiratory syndrome 2 (SARS-CoV-2) waves, including the impact of different measures, are lacking. This cohort study, conducted from March 2020 to May 2023 Toronto, Canada, aimed analyze COVID-19 1975 SOTr various SARS-CoV-2 waves and assess preventive treatment measures. The primary outcome was COVID-19, defined as requiring supplemental oxygen, with secondary...
The HeartWare ventricular assist device (HVAD) is a new generation centrifugal flow VAD recently introduced in Canada. objective of this study was to compare the HVAD HeartMate II (HMII) axial device. Very few studies have compared clinical outcomes between newer VADs.All perioperative and follow-up data on LVAD recipients were collected prospectively our institutional database. Between January 2006 April 2012, 46 consecutive patients underwent implantation either an (n=13) or HMII (n=33)...
The mRNA vaccines against COVID-19 infection have been effective in reducing the number of symptomatic cases worldwide. With widespread uptake, case series vaccine-related myocarditis/pericarditis reported, particularly adolescents and young adults. Men tend to be affected with greater frequency, symptom onset is usually within 1 week after vaccination. Clinical course appears mild most cases. On basis available evidence, we highlight a clinical framework guide providers on how assess,...
Abstract We present star formation rates (SFRs), the mass–metallicity relation (MZR), and SFR-dependent MZR across redshifts 4–10 using 81 star-forming galaxies observed by JWST NIRSpec employing both low-resolution PRISM medium-resolution gratings, including from Advanced Deep Extragalactic Survey (JADES) GOODS-N GOODS-S fields, JWST-PRIMAL Legacy Survey, additional literature in A2744, SMACS-0723, RXJ2129, BDF, COSMOS, MACS1149 fields. These span a 3 dex stellar mass range of 10 7 < M *...
A novel dual-labeled nanoparticle for use in labeling and tracking cells vivo is described. We report the construction characterization of these gadolinium−rhodamine nanoparticles. These particles are constructed from lipid monomers with diacetylene bonds that sonicated photolyzed to form polymerized Cells efficiently labeled have inoculated tumor subcutaneouosly into flanks C3H mice been able image via MRI optical imaging. Furthermore, can be visualized fluorescent microscopy after tissue...
Since 1998, U.S. House incumbents have won a staggering 98 percent of their reelection races. Electoral competition has also declined in some state and primary elections. The Marketplace for Democracy combines the resources two eminent research organizations --Brookings Cato Institute --to address several important questions about our democratic system. How pervasive is lack arenas only previously speculated on, such as legislative contests congressional primaries? What previous reform...
Background . Right ventricular (RV) dysfunction during cancer therapy related cardiotoxicity and its prognostic implications have not been examined. Aim We sought to determine the incidence value of RV at time LV defined cardiotoxicity. Methods retrospectively identified 30 HER2+ female patients with breast treated trastuzumab (± anthracycline) who developed had a diagnostic quality transthoracic echocardiography. ejection fraction (LVEF), fractional area change (RV FAC), peak systolic...
AbstractCoronavirus disease 2019 (COVID-19) has resulted in public health measures and care reconfigurations likely to have impact on chronic care. We aimed assess the volume characteristics of patients presenting hospitals with acute decompensated heart failure (ADHF) during 2020 COVID-19 pandemic compared a time-matched cohort. Patients ADHF from March 1, April 19, an urban hospital were examined. Multivariable logistic-regression models used evaluate difference probability ADHF-related...
Tau pathology, a hallmark of Alzheimer's disease, is observed in the brains virtually all individuals over 70 years. Using 18F-AV-1451 (18F-flortaucipir) positron emission tomography, we evaluated tau pathology 54 cognitively normal participants (mean age: 77.5 years, SD: 8.9) from Baltimore Longitudinal Study Aging. We assessed associations between tomography signal and age, sex, race, amyloid positivity. investigated relationships regional retrospective rates change volumes cognitive...
KEY POINTS The goal of the Canadian Cardiovascular Harmonized National Guideline Endeavour (C-CHANGE) process is to give all health care providers easy access a comprehensive and practical set harmonized guideline recommendations. Clinicians claim that there are too many guidelines
The α7 nicotinic acetylcholine receptor increasingly has been implicated in normal brain physiology, as well neuropsychiatric disorders. highly cortical distribution of suggests a role cognition. We expanded the first-in-human PET imaging with [18F]ASEM from 5 to 21 healthy nonsmoking volunteers and added feasibility study 6 male patients schizophrenia. Study aims included: (1) confirmation test-retest reproducibility binding, (2) demonstration specificity by competition DMXB-A, an partial...
TRUST IS FUNDAMENTAL in health research, yet there is little empirical evidence that explores the meaning of trust from perspective human subjects. The analysis presented here focuses on how subjects talked about in-depth interviews. It emerged accounts could not be assumed research setting, rather it was portrayed as a dynamic concept, built and easily broken, characterized by reciprocity negotiation. Human were ambivalent who, when, what, much to endeavor. This paper adds fresh literature...