- Plant tissue culture and regeneration
- Gastrointestinal motility and disorders
- MicroRNA in disease regulation
- Photovoltaic System Optimization Techniques
- Liver Disease Diagnosis and Treatment
- Wheat and Barley Genetics and Pathology
- Inflammatory Bowel Disease
- Plant-Microbe Interactions and Immunity
- Cancer-related molecular mechanisms research
- Gastroesophageal reflux and treatments
- Solar Radiation and Photovoltaics
- Glass properties and applications
- Infant Health and Development
- Circular RNAs in diseases
- Optical Network Technologies
- RNA modifications and cancer
- Research in Cotton Cultivation
- Genetic Mapping and Diversity in Plants and Animals
- Plant Pathogenic Bacteria Studies
- Neuropeptides and Animal Physiology
- Soft Robotics and Applications
- Plant Virus Research Studies
- Bacteriophages and microbial interactions
- Silicon and Solar Cell Technologies
- Gastric Cancer Management and Outcomes
Renmin Hospital of Wuhan University
2014-2025
Wuhan University
2014-2025
Wuhan Prevention and Treatment Center for Occupational Diseases
2025
Beijing Solar Energy Research Institute
2021-2024
Sichuan University
2022-2024
Harbin Institute of Technology
2022-2024
National Renewable Energy Laboratory
2023
UL Research Institutes
2023
Intertek (United States)
2023
University of North Carolina at Charlotte
2023
Despite recent advances in treatment of viral hepatitis, liver-related mortality is high, possibly owing to the large burden advanced alcohol-related liver disease (ALD). We investigated whether patients with ALD are initially seen at later stages development than hepatitis C virus (HCV) infection or other etiologies.We performed a cross-sectional study 3453 consecutive either early (1699 and 1754 disease) 17 tertiary care gastrointestinal units worldwide, from August 2015 through March...
• Although the role of auxin in biotrophic pathogenesis has been extensively studied, relatively little is known about its plant resistance to necrotrophs. Arabidopsis thaliana mutants defective different aspects pathway are generally more susceptible than wild-type plants necrotrophic pathogen Alternaria brassicicola. We show that A. brassicicola infection up-regulates biosynthesis and down-regulates transport capacities infected plants, these effects being partially dependent on JA...
Abstract Assessment of colonic motor dysfunction is rarely done because inadequate methodology and lack knowledge about normal patterns. Here we report on elucidation intraluminal pressure patterns using High Resolution Colonic Manometry during a baseline period in response to meal, 15 patients with constipation, chronically dependent laxatives, 5 healthy volunteers 9 minor, transient, IBS-like symptoms but no sign constipation. Simultaneous waves (SPWs) were the most prominent propulsive...
Background and Aims Better understanding of intrinsic control mechanisms colonic motility will lead to better treatment options for dysmotility. The aim was investigate neurogenic myogenic underlying pan-colonic motor patterns. Methods Analysis in vitro video recordings whole rat colon used explore patterns their spatiotemporal organizations identify using pharmacological tools. Results Study the organization revealed: fluid-induced or spontaneous rhythmic propulsive long distance...
Ulcerative colitis (UC), a major type of inflammatory bowel disease, is also chronic non-specific intestinal inflammation condition unknown etiology. The pathogenesis UC closely associated with immune abnormalities, damage and genetics. present study aimed to explore the effects microRNA (miR)-21-5p on interleukin-6 (IL-6) receptor (IL6R)/signal transducer activator transcription (STAT3) signal pathway in UC, order identify highly effective treatment for UC. A total 45 patients healthy...
Phase-amplitude coupling of two pacemaker activities the small intestine, omnipresent slow wave activity generated by interstitial cells Cajal myenteric plexus (ICC-MP) and stimulus-dependent rhythmic transient depolarizations ICC deep muscular (ICC-DMP), was recently hypothesized to underlie orchestration segmentation motor pattern. The aim present study increase our understanding phase-amplitude through modeling. In particular importance propagation velocity ICC-DMP component investigated....
BACKGROUND Worldwide, dietary changes have resulted in an increased incidence of colorectal cancer (CRC). Circular RNAs (circRNAs) are involved tumorigenesis several human tumors, but their role CRC remains unknown. This study aimed to investigate the expression and effects Homo sapiens (hsa)_circ_0079993 POLR2J4 its impact on CRC. MATERIAL AND METHODS Paired tissue adjacent normal samples (N=41), HCT116 SW620 cells were studied. The circ_0079993 parental gene, POLR2J4, examined using...
Introduction: The completeness of esophagogastroduodenoscopy (EGD) is a prerequisite for detecting lesions. This study aims to explore whether the quality complete examinations assisted by artificial intelligence (AI) would be comparable those conducted within guideline-recommended inspection time. Methods: Patients referred diagnostic, screening, or surveillance EGD were enrolled at Renmin Hospital Wuhan University. randomly assigned two groups in 1:1 ratio. In AI-assisted group,...
Oxidative stress and chronic inflammation are major culprits of nonalcoholic fatty liver disease (NAFLD). MicroRNA-665-3p (miR-665-3p) is implicated in regulating oxidative stress; however, its role molecular basis NAFLD remain elusive. Herein, we measured a significant upregulation miR-665-3p level the primary hepatocytes upon high fat diet (HFD) or 0.5 mmol/L palmitic acid plus 1.0 oleic stimulation, elevated expression aggravated stress, progression mice. In contrast, inhibition by...
The Poaceae family is of great importance to human beings since it comprises the cereal grasses which are main sources for food and animal feed. With rapid growth genomic data from members, comparative genomics becomes a convinent method study genetics diffierent species. SSRs (Simple Sequence Repeats) widely used markers in studies their high abundance stability. In this study, using sequences 9 species, we detected 11,993,943 SSR loci developed 6,799,910 primer pairs. results show that...
Recently, semantic segmentation and general object detection frameworks have been widely adopted by scene text detecting tasks. However, both of them alone obvious shortcomings in practice. In this paper, we propose a novel end-to-end trainable deep neural network framework, named Pixel-Anchor, which combines SSD one feature sharing anchor-level attention mechanism to detect oriented text. To deal with has large variances size aspect ratio, combine FPN ASPP operation as our encoder-decoder...
Cable-Driven Parallel Robots (CDPRs) have been proposed for a variety of applications such as material handling, rehabilitation, and instrumentation. However, the collision-free constraint CDPRs limits workspace feasible position anchor points. To address CDPRs, data-driven kinematic control scheme is developed enabling CDPR to its pose even if suffering collisions between cable base or end-effector. deal with collisions, utilizes motion model obtained based on data samples CDPR, rather than...
Abstract To explore the targeting relationship between miR‐490‐5p and ECT2 in hepatocellular carcinoma (HCC) influences of on stemness HCC cells. The expressions tissues adjacent were identified by quantitative real‐time polymerase chain reaction (qRT‐PCR). relationships expression levels miR‐490‐5p/ overall/disease‐free survival (OS/DFS) patients with evaluated using correlative curves. In addition, was predicted TargetScan verified dual‐luciferase reporter assay. Plasmid transfection used...
Abstract Scholars have proposed to allow cables wrap on the base, end-effector, or obstacles expand workspace of a cable-driven parallel robot (CDPR) in recent years. However, it is not entirely clear whether path cable wrapped surface different rigid bodies can cannot be solved analytically. To this end, paper analyzes statics general and proposes necessary conditions for frictionless surface. This shows that only included handful surfaces, including cylinders spheres, Then, inverse...