A5087485359- Balance, Gait, and Falls Prevention
- Cancer survivorship and care
- Cerebral Palsy and Movement Disorders
- Neuroscience of respiration and sleep
- Obstructive Sleep Apnea Research
- Angiogenesis and VEGF in Cancer
- Sleep and Wakefulness Research
- Frailty in Older Adults
- Heart Rate Variability and Autonomic Control
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Childhood Cancer Survivors' Quality of Life
- Stroke Rehabilitation and Recovery
- Neonatal and fetal brain pathology
- Renal Transplantation Outcomes and Treatments
- Neuroscience and Neuropharmacology Research
- Gastrointestinal motility and disorders
- Pharmacological Effects and Toxicity Studies
- Pelvic floor disorders treatments
- Multiple Sclerosis Research Studies
- Nutrition and Health in Aging
- Scoliosis diagnosis and treatment
- Effects of Vibration on Health
- Studies on Chitinases and Chitosanases
- Lymphatic System and Diseases
- Asthma and respiratory diseases
Hunan Children's Hospital
2011-2025
Fujian Medical University
2021-2025
Changzhi Medical College
2025
Central South University
2025
University of Michigan–Flint
2015-2024
Jilin University
2007-2024
First Affiliated Hospital of Fujian Medical University
2021-2024
Shanghai Children's Hospital
2016-2023
Sun Yat-sen University
2005-2023
Committee on Publication Ethics
2023
<b>Background:</b> There is almost no longitudinal information about measured cognitive performance during the menopause transition (MT). <b>Methods:</b> We studied 2,362 participants from Study of Women9s Health Across Nation for 4 years. Major exposures were time spent in MT stages, hormone use prior to final menstrual period, and postmenopausal current use. Outcomes three domains: processing speed (Symbol Digit Modalities Test [SDMT]), verbal memory (East Boston Memory [EBMT]), working...
Abstract Assessment of colonic motor dysfunction is rarely done because inadequate methodology and lack knowledge about normal patterns. Here we report on elucidation intraluminal pressure patterns using High Resolution Colonic Manometry during a baseline period in response to meal, 15 patients with constipation, chronically dependent laxatives, 5 healthy volunteers 9 minor, transient, IBS-like symptoms but no sign constipation. Simultaneous waves (SPWs) were the most prominent propulsive...
Preeclampsia (PE) is associated with increased total peripheral resistance (TPR), reduced cardiac output (CO), and diminished uterine placental blood flow. We have developed an animal model that employs chronic reductions in perfusion pressure (RUPP) pregnant rats to generate a "preeclamptic-like" state during late gestation characterized by hypertension, proteinuria, endothelial dysfunction. Although this has many characteristics of human PE, the systemic hemodynamic regional changes flow...
Objective: To assess the relationship between severity of neurogenic bowel and health-related quality life in persons with various degrees spinal cord injury.Design: Cross-sectional.Subjects: A total 128 people injury.Methods: Two questionnaires were sent out by post.One included demographic characteristics a dysfunction score to evaluate dysfunction.The other was Short-Form 36-Item Health Survey that evaluated injury.Results: Approximately half injury (46.9%) had moderate severe...
Obese postmenopausal women have a 50% higher risk of breast cancer than non-obese women. There is not an animal model that mimics obesity related to progression. Using age-relevant C57BL/6 mice, this study determined whether increases VEGF expression, tumor angiogenesis, and growth. Ovariectomy (OVX) was performed in 12 sixty week-old female then followed by low-fat (5%, LF, n=6) or high-fat (60%, HF, diet for weeks. In the eighth week dietary program, 10^6 E0771 (mouse cancer) cells were...
We previously reported that the ethanol extract of <i>Schisandra sphenanthera</i> [Wuzhi (WZ) tablet] significantly protects against acetaminophen-induced hepatoxicity. However, whether WZ exerts a protective effect cholestasis remains unclear. In this study, on lithocholic acid (LCA)–induced intrahepatic in mice was characterized and involved mechanisms were investigated. pretreatment (350 mg/kg) with LCA reversed liver necrosis decreased serum alanine aminotransferase, aspartate alkaline...
Abstract Objective Admission hyperglycemia is associated with poor prognosis in patients acute myocardial infarction (AMI), but the effects of baseline diabetes status on this association remain elusive. We aim to investigate impact admission short and long-term outcomes diabetic non-diabetic AMI patients. Methods In retrospective cohort study, 3330 regard first-time between July 2012 2020 were identified. Participants divided into two groups according (1060 2270 patients). Thereafter, they...
Abstract There is little information on changes in overall and regional hemodynamics obesity-associated hypertension. Therefore, the purpose of this study was to determine alterations blood flows resistances adipose nonadipose tissues a new model hypertension rabbits. Sixteen female New Zealand White rabbits were fed either maintenance or high-fat diet; after 8 12 weeks cardiac output measured with use radioactive microspheres. Obese (5.22±0.14 versus 3.66±0.04 kg) had higher pressure (113±3...
Cancer is primarily a disease of older adults. About 77% all cancers are diagnosed in persons aged 55 years and older. its treatment can cause diverse sequelae impacting body systems underlying balance control. No study has examined the psychometric properties assessment tools cancer survivors, presenting significant challenge selection outcome measures for clinicians treating this fast-growing population.This aimed to determine reliability, validity, minimal detectable change (MDC) Balance...
Newborn Screening Programme for Congenital Heart Disease (CHD) in Shanghai has been operation over 5 years, and its feasibility effectiveness still lack a systematic comprehensive evaluation. This study aimed to detail the implementation of programme evaluate results, benefits, reliability clinical practice.This was an observational involving all newborns received CHD screening from 2017 2021. Pulse oximetry (POX) plus cardiac murmur auscultation (namely dual-index method) used aged 6-72 h....
Objective:To explore the feasibility of endoscopic-assisted resection congenital first and second branchial cleft malformations in children via external fistula incision approach. Methods:A retrospective analysis was conducted on 20 with who were admitted to Department Otolaryngology Head Neck Surgery Hu'nan Children's Hospital from January 2020 2024 whose families voluntarily consented endoscopic surgery. Clinical data collected. There 12 males 8 females, aged 10 months years. The surgical...
Physical ailments and mental illness among college students are surging in recent years, which warrants urgent comprehensive health research. To investigate whether there is a disparity allostatic load between medical non-medical students, to identify the influencing factors on load. A cross-sectional study involving 8,253 was conducted. We used modified Poisson regression analysis of generalized linear models examine two groups based biological, psychological, sociological factors. The...
A telehealth-delivered Otago program for rural older adults aged ≥60 years was evaluated. Participants (n = 18) received one-on-one Zoom visits at homes during the initial 4 weeks and used an exercise app up to 24 weeks. Retention dropped from 67% 8 44% weeks, due technical challenges 5), disinterest in online format 3), illness 3). No safety concerns arose. At 12 most participants improved their performance on 30-Second Chair Stand Timed-Up-Go. Despite functional gains, barriers...
The administration of glucose has been shown to worsen brain injury in adult animals but no effect on the severity newborn rats. We wished see whether results rats could be extended another animal.In 44 0- 3-day-old piglets, hypoxic-ischemic central nervous system damage was induced by ligation both carotid arteries and reduction their blood pressure two-thirds normal for one-half hour. In last 15 minutes this half hour, oxygen concentration reduced 6%. piglets were randomized receive either...
Giving glucose before hypoxic ischemia worsens brain injury in piglets. Does giving after affect severity of injury? Forty-three 0- to 3-day-old pigs were used. All piglets received 2 U/kg insulin prevent stress-induced hyperglycemia. Hypoxic ischemic damage was induced by clamping both carotid arteries and reducing arterial blood pressure two thirds normal hemorrhage at time 0. At 15 minutes the fraction inspired oxygen (FIO2) reduced 6%. 30 FIO2 increased 100%, carotids released, withdrawn...
To evaluate serum inflammatory markers of YKL-40, Interleukin-6 (IL-6), Interleukin-8(IL-8), Interleukin-10(IL-10), TNF-α(tumor necrosis factor-α), and CRP (C-reactive protein) in children with without OSAS.The ELISA technique has been used to identify the concentration such as IL-6, IL-8, IL-10, TNF-α, 83 OSAS OSAS.Serum levels IL-10 were found be increased OSAS. YKL-40 was positively correlated IL-6 negatively IL-10. At same time,YKL-40 also OAHI LoSpO2% group. IL-8 whereas LoSpO2.Children...
We intend to explore whether sleep duration and patterns were associated with obesity among the adult American population. Our study analyzed data from 4540 adults (2007-2008, 2015-2018) in National Health Nutrition Examination Survey (NHANES) database. Self-reported questionnaires used collect on duration, excessive daytime sleepiness, problems. The overall pattern score was calculated categorized into three types: healthy, intermediate, poor patterns. Multivariable logistic regression...