Zhen Yu Wong

ORCID: 0000-0002-0950-8981
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Liver Disease and Transplantation
  • Cutaneous Melanoma Detection and Management
  • Facial Nerve Paralysis Treatment and Research
  • Diet, Metabolism, and Disease
  • Alcohol Consumption and Health Effects
  • Reconstructive Facial Surgery Techniques
  • Botulinum Toxin and Related Neurological Disorders
  • Bariatric Surgery and Outcomes
  • Ear Surgery and Otitis Media
  • Reconstructive Surgery and Microvascular Techniques
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cell Image Analysis Techniques
  • Orthopedic Surgery and Rehabilitation
  • Nonmelanoma Skin Cancer Studies
  • Diversity and Career in Medicine
  • Pregnancy and Medication Impact
  • Health Systems, Economic Evaluations, Quality of Life
  • Body Image and Dysmorphia Studies
  • Organ Transplantation Techniques and Outcomes
  • Facial Rejuvenation and Surgery Techniques
  • Digital Imaging in Medicine
  • Colorectal Cancer Screening and Detection
  • Nutrition and Health in Aging
  • Wound Healing and Treatments

Nottingham University Hospitals NHS Trust
2022-2025

Queen's Medical Centre
2024-2025

National Health Service
2025

Manipal University College Malaysia
2024-2025

University College London
2025

The Royal Free Hospital
2025

Morriston Hospital
2024-2025

Johns Hopkins Medicine
2025

Johns Hopkins University
2025

Nottingham City Hospital
2022-2024

Hypertension (HTN) is a common comorbidity in non-alcoholic fatty liver disease (NAFLD) affecting up to 40% of individuals. However, the impact HTN and its control on outcomes NAFLD remains unclear. Therefore, we aimed examine survival longitudinal cohort patients.

10.3389/fcvm.2022.942753 article EN cc-by Frontiers in Cardiovascular Medicine 2022-08-08

This study aimed to assess the burden and economic impact of disease associated with plastic reconstructive surgery in United Kingdom. We calculated a value per statistical life year £60,000 person Kingdom ($75,510 U.S. dollars). found that 2019, estimated age-standardized incident rates, death disability-adjusted years surgery-related conditions were 361.47 100,000, 19.5 100,000 551.0 respectively. Burn emerged as leading contributor overall burden, accounting for 32%, followed by decubitus...

10.1097/psn.0000000000000589 article EN Plastic and Aesthetic Nursing 2025-03-30

Non-alcoholic fatty liver disease (NAFLD) represents a significant health threat worldwide. The growing trend towards an aging population, along with alarming rise in obesity and diabetes, may have implications for the burden of NAFLD.To assess impact NAFLD on elderly.We utilised data from Global Burden Disease study between 2010 2019 to conduct comprehensive analysis prevalence, mortality, disability-adjusted life years (DALYs) associated elderly (65-89 years), stratified by region, nation,...

10.1111/apt.17714 article EN Alimentary Pharmacology & Therapeutics 2023-09-11

Background and Aims: Obeticholic acid (OCA) is a farnesoid X receptor agonist used in primary biliary cholangitis (PBC) treatment. Recent studies have expanded OCA use for NASH treatment results from phase 3 clinical trial shown beneficial reduction of ≥1 stage fibrosis with no worsening. However, safety concerns still preside, thus we systematically examine the profile chronic liver disease. Materials Methods: A search was conducted Medline Embase databases randomized controlled trials...

10.1097/hc9.0000000000000005 article EN cc-by-nc-nd Hepatology Communications 2023-02-09

Abstract Objective With rising prevalence of hypertension and obesity, the effect in obesity remains an important global issue. The prognosis US general population with based on control was examined. Methods This study examined participants from National Health Nutrition Examination Survey between 1999 2018. Individuals were stratified into no hypertension, controlled uncontrolled hypertension. outcome all‐cause mortality. Cox regression mortality adjusted for age, sex, ethnicity, diabetes,...

10.1002/oby.23658 article EN Obesity 2023-02-07

The etiology of liver diseases has changed significantly, but its impact on the comparative burden cirrhosis between males and females is unclear. We estimated sex differences in across 204 countries territories from 2010 to 2019.

10.1159/000533946 article EN cc-by Digestive Diseases 2023-01-01

Fatty liver is the commonest condition globally and traditionally associated with NAFLD. A consensus meeting was held in Chicago to explore various terminologies. Herein, we proposed changes nomenclature a population data set from US.Statistical analysis conducted using survey-weighted analysis. Assessment of fatty vibration-controlled transient elastography. controlled attenuation parameter 288 dB/m used identify hepatic steatosis. Patients were classified into nonalcoholic steatotic...

10.1097/hep.0000000000000043 article EN Hepatology 2023-01-03

Hand microsurgery is an important advancement of the speciality that has improved outcomes in hand trauma and surgical conditions. This bibliometric analysis aims to identify 75 most cited articles explore their relevance contemporary practice. The Web Science core collection database was used screen top most-cited relevant microsurgery. VOSviewer 1.6.18 CiteSpace 6.2.R4 software were analyse visualise occurrences, authorship, countries, institutions, journals, keywords, Evidence Level...

10.1016/j.jham.2025.100214 article EN Journal of Hand and Microsurgery 2025-01-05

Abstract Background Botulinum toxin is widely used in aesthetic medicine, with numerous studies examining its efficacy and safety. Objectives This bibliometric analysis aims to describe research trends assess the methodological quality of highest-impact botulinum applications. Methods The authors this study identified 100 most-cited publications on aesthetics using Web Science, covering all available journal years (from inception October 2024). Oxford Centre for Evidence-Based Medicine Level...

10.1093/asjof/ojae131 article EN cc-by Aesthetic Surgery Journal Open Forum 2025-01-01

This bibliometric analysis aimed to define important topics and developments across wide awake local anaesthesia no tourniquet (WALANT) hand surgery, an innovative ambulatory technique that gained popularity during the COVID-19 pandemic. Articles were searched screened using Web of Science core collection database. VOSviewer 1.6.18 bibliometrix used for analysis. In initial search 419 articles found. Between 1990 2023, 333 writers contributed top 100 most-cited published. The country with...

10.1177/17531934241313205 article EN Journal of Hand Surgery (European Volume) 2025-01-25

Cutaneous melanoma (CM) is a rare occurrence in the pediatric population and suffers from dearth of epidemiological data. This study aims to estimate distribution temporal trends CM. Data specific (<20 years old) CM were extracted Global Burden Disease (GBD) Study 2019, stratified by Socio-demographic Index (SDI) WHO region. The data encompassed incidence, mortality, disability-adjusted life-years (DALYs) representing healthy life lost due diagnosis. Join point regression analysis Quality...

10.1080/08880018.2025.2466023 article EN Pediatric Hematology and Oncology 2025-02-24

Abstract Androgen deprivation therapy (ADT) is the mainstay of PC treatment for lethal, recurrent and metastatic prostate cancer (PCa). Although initial response rate to ADT high, invariably fails as cells become resistant progress into a castration-resistant stage called (CRPC). Based on long-standing paradoxical observation that growth PCa could be inhibited by supraphysiologic testosterone (SupraT) treatment, we devised bipolar androgen (BAT) treat CRPC. BAT involves rapid cycling between...

10.1158/1538-7445.am2025-6177 article EN Cancer Research 2025-04-21

This bibliometric analysis aims to describe research trends and assess the methodological quality of highest-impact SLNB in melanoma. We identified 90 most cited publications on melanoma using Web Science, covering all available journal years (from 2005 date). The Oxford Center for Evidence-Based Medicine (OCEBM) Levels Evidence (LOE) were used each study. collectively garnered 10,314 citations. Citation counts per publication ranged from 44 1,405 (mean 114.6 ± 185.2), with highest-cited...

10.1080/20450885.2025.2494979 article EN cc-by-nc Melanoma Management 2025-04-28

Background. Liver transplantation (LT) offers patients with decompensated cirrhosis the best chance at long-term survival. With rising prevalence of diabetes, further clarity is needed on impact receiving a liver allograft from donor diabetes post-LT outcomes. This study aims to evaluate clinical outcomes after LT. Methods. retrospective analysis United Network for Organ Sharing registry data LT recipients January 1, 2000, December 31, 2021. Outcomes was performed using Cox proportional...

10.1097/tp.0000000000004718 article EN Transplantation 2023-07-12
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